“Living a normal life”: a qualitative study of patients’ views of medication withdrawal in rheumatoid arthritis by Kenneth F. Baker, John D. Isaacs, Ben Thompson

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4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]-1,2-dihydroquinoline-3-carboxamide by Emmanuel S. Akinboye, Ray J. Butcher, Sema Ozturk Yildirim, John T. Isaacs

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Introducing New Biosimilars Into Current Treatment Algorithms by John D. Isaacs, Thomas Dörner, Tore K. Kvien, Arnold Vulto

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Evaluating Awareness and Perception of Botnet Activity within Consumer Internet-of-Things (IoT) Networks by Christopher D. McDermott, John P. Isaacs, Andrei V. Petrovski

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Mipsagargin: The Beginning—Not the End—of Thapsigargin Prodrug-Based Cancer Therapeutics by John T. Isaacs, William Nathaniel Brennen, Søren Brøgger Christensen, Samuel R. Denmeade

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Lack of association between clinical and ultrasound measures of disease activity in rheumatoid arthritis remission by Kenneth F. Baker, Ben Thompson, Dennis W. Lendrem, Adam Scadeng, Arthur G. Pratt, John D. Isaacs

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Rheumatoid Arthritis Prevention: catalysing PlatfORm Trial delivery (RAPPORT) by Michelle Bardgett, Marie Falahee, Gwenda Simons, John D Isaacs, Luke Ouma, James MS Wason, Arthur G Pratt

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IL-6 Mediated Transcriptional Programming of Naïve CD4+ T Cells in Early Rheumatoid Arthritis Drives Dysregulated Effector Function by Laura A. Ridgley, Amy E. Anderson, Nicola J. Maney, Najib Naamane, Andrew J. Skelton, Catherine A. Lawson, Catherine A. Lawson, Paul Emery, Paul Emery, John D. Isaacs, John D. Isaacs, Ruaidhrí J. Carmody, Arthur G. Pratt, Arthur G. Pratt

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Loss of androgen receptor-dependent growth suppression by prostate cancer cells can occur independently from acquiring oncogenic addiction to androgen receptor signaling. by Jason M D'Antonio, Donald J Vander Griend, Lizamma Antony, George Ndikuyeze, Susan L Dalrymple, Shahriar Koochekpour, John T Isaacs

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Phenotypic and Transcriptomic Analysis of Peripheral Blood Plasmacytoid and Conventional Dendritic Cells in Early Drug Naïve Rheumatoid Arthritis by Faye A. H. Cooles, Faye A. H. Cooles, Amy E. Anderson, Amy E. Anderson, Andrew Skelton, Andrew Skelton, Arthur G. Pratt, Arthur G. Pratt, Mariola S. Kurowska-Stolarska, Mariola S. Kurowska-Stolarska, Iain McInnes, Iain McInnes, Catharien M. U. Hilkens, Catharien M. U. Hilkens, John D. Isaacs, John D. Isaacs

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Fluorine labelling of therapeutic human tolerogenic dendritic cells for 19F-magnetic resonance imaging by Fiona Cooke, Fiona Cooke, Mary Neal, Mary Neal, Matthew J. Wood, Matthew J. Wood, I. Jolanda M. de Vries, Amy E. Anderson, Amy E. Anderson, Julie Diboll, Julie Diboll, Arthur G. Pratt, Arthur G. Pratt, Arthur G. Pratt, James Stanway, James Stanway, Ioana Nicorescu, Ioana Nicorescu, Nicholas Moyse, Dawn Hiles, David Caulfield, Anne M. Dickinson, Andrew M. Blamire, Andrew M. Blamire, Pete Thelwall, Pete Thelwall, John D. Isaacs, John D. Isaacs, John D. Isaacs, Catharien M. U. Hilkens, Catharien M. U. Hilkens

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FcγRIIIa expression on monocytes in rheumatoid arthritis: role in immune-complex stimulated TNF production and non-response to methotrexate therapy. by Dawn L Cooper, Stephen G Martin, James I Robinson, Sarah L Mackie, Christopher J Charles, Jackie Nam, YEAR Consortium, John D Isaacs, Paul Emery, Ann W Morgan

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Operational complexities in international clinical trials: a systematic review of challenges and proposed solutions by John D Isaacs, Dawn Craig, Jingky Lozano-Kuehne, Arthur G Pratt, Michelle Bardgett, Madeleine Still, Leher Gumber, Luke Ouma, Opeyemi Agbeleye, Alex Inskip, Ross Fairbairn, James MS Wason

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Population Pharmacokinetic Analysis and Simulation of Alternative Dosing Regimens for Biosimilars to Adalimumab and Etanercept in Patients with Rheumatoid Arthritis by Stephanie F. Ling, Kayode Ogungbenro, Adam S. Darwich, Amirah Binti Mohammad Ariff, Nisha Nair, James Bluett, Ann W. Morgan, John D. Isaacs, Anthony G. Wilson, Kimme L. Hyrich, Anne Barton, Darren Plant

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Targeting of tolerogenic dendritic cells to heat-shock proteins in inflammatory arthritis by Rachel Spiering, Manon A. A. Jansen, Matthew J. Wood, Anshorulloh A. Fath, Oliver Eltherington, Amy E. Anderson, Arthur G. Pratt, Willem van Eden, John D. Isaacs, Femke Broere, Catharien M. U. Hilkens

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Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission by Kenneth F. Baker, David McDonald, Gillian Hulme, Rafiqul Hussain, Jonathan Coxhead, David Swan, Axel R. Schulz, Henrik E. Mei, Lucy MacDonald, Arthur G. Pratt, Andrew Filby, Amy E. Anderson, John D. Isaacs

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In Reply by W. Nathaniel Brennen, Michael T. Schweizer, Hao Wang, Trinity J. Bivalacqua, Alan W. Partin, Su Jin Lim, Carolyn Chapman, Rehab Abdallah, Oren Levy, Neil A. Bhowmick, Jeffrey M. Karp, Angelo De Marzo, John T. Isaacs, Samuel R. Denmeade

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Monitoring immunE DysregulAtion foLLowing Immune checkpOint-inhibitioN (MEDALLION): protocol for an observational cancer immunotherapy cohort study by Abigail Gault, Linda Hogarth, Kristian C Williams, Alastair Greystoke, Neil Rajan, Ally Speight, Christopher A Lamb, Alison Bridgewood, Lisa-Jayne Brown-Schofield, Fiona Rayner, John D Isaacs, Jérémie Nsengimana, Christopher J Stewart, Amy E Anderson, Ruth Plummer, Arthur G Pratt

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Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer by W. Nathaniel Brennen, Yezi Zhu, Ilsa M. Coleman, Susan L. Dalrymple, Lizamma Antony, Radhika A. Patel, Brian Hanratty, Roshan Chikarmane, Alan K. Meeker, S. Lilly Zheng, Jody E. Hooper, Jun Luo, Angelo M. De Marzo, Eva Corey, Jianfeng Xu, Srinivasan Yegnasubramanian, Michael C. Haffner, Peter S. Nelson, William G. Nelson, William B. Isaacs, John T. Isaacs

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Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis by Frank Penkava, Martin Del Castillo Velasco-Herrera, Matthew D. Young, Nicole Yager, Lilian N. Nwosu, Arthur G. Pratt, Alicia Lledo Lara, Charlotte Guzzo, Ash Maroof, Lira Mamanova, Suzanne Cole, Mirjana Efremova, Davide Simone, Andrew Filer, Chrysothemis C. Brown, Andrew L. Croxford, John D. Isaacs, Sarah Teichmann, Paul Bowness, Sam Behjati, M. Hussein Al-Mossawi

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