Editorial: Alveolar Macrophages in Lung Inflammation and Resolution by Guochang Hu, John W. Christman

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3308 Training KL2 Scholars to Communicate Science to a General Audience by Cynthia Ann Carnes, John W. Christman, Mark Damian Wewers, Stuart D Hobbs, Rebecca Jackson

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Epigallocatechin gallate regulates the myeloid-specific transcription factor PU.1 in macrophages. by Manjula Karpurapu, Kavita Kumari Kakarala, Sangwoon Chung, Yunjuan Nie, Amritendu Koley, Patrick Dougherty, John W Christman

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Intratracheal instillation of high dose adenoviral vectors is sufficient to induce lung injury and fibrosis in mice. by Qiyuan Zhou, Tianji Chen, Melike Bozkanat, Joyce Christina F Ibe, John W Christman, J Usha Raj, Guofei Zhou

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Lipopolysaccharide-induced expression of microsomal prostaglandin E synthase-1 mediates late-phase PGE2 production in bone marrow derived macrophages. by Lei Xiao, Magdalena Ornatowska, Guiqing Zhao, Hongmei Cao, Rui Yu, Jing Deng, Yongchao Li, Qiong Zhao, Ruxana T Sadikot, John W Christman

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TLR4 Expression by Liver Resident Cells Mediates the Development of Glucose Intolerance and Insulin Resistance in Experimental Periodontitis. by Vladimir Ilievski, Yale Cho, Priya Katwala, Heriberto Rodriguez, Margaret Tulowiecka, David Kurian, Lara Leoni, John W Christman, Terry G Unterman, Keiko Watanabe

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PolyADP-Ribosylation of NFATc3 and NF-κB Transcription Factors Modulate Macrophage Inflammatory Gene Expression in LPS-Induced Acute Lung Injury by Yunjuan Nie, Teja Srinivas Nirujogi, Ravi Ranjan, Brenda F. Reader, Sangwoon Chung, Megan N. Ballinger, Joshua A. Englert, John W. Christman, Manjula Karpurapu

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Krüppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation. by Manjula Karpurapu, Ravi Ranjan, Jing Deng, Sangwoon Chung, Yong Gyu Lee, Lei Xiao, Teja Srinivas Nirujogi, Jeffrey R Jacobson, Gye Young Park, John W Christman

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The calcineurin–NFATc pathway modulates the lipid mediators in BAL fluid extracellular vesicles, thereby regulating microvascular endothelial cell barrier function by Manjula Karpurapu, Yunjuan Nie, Sangwoon Chung, Jiasheng Yan, Patrick Dougherty, Sonal Pannu, Jon Wisler, Ryan Harkless, Narasimham Parinandi, Evgeny Berdyshev, Dehua Pei, John W. Christman

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Early Titration of Oxygen During Mechanical Ventilation Reduces Hyperoxemia in a Pilot, Feasibility, Randomized Control Trial for Automated Titration of Oxygen Levels by Sonal R. Pannu, MD, MSc, Matthew Exline, MD, MPH, Brett Klamer, MS, Guy Brock, PhD, Elliott D. Crouser, MD, John W. Christman, MD, Philip Diaz, MD

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Lipidomic Profiling of Bronchoalveolar Lavage Fluid Extracellular Vesicles Indicates Their Involvement in Lipopolysaccharide-Induced Acute Lung Injury by Teja Srinivas Nirujogi, Sainath R. Kotha, Sangwoon Chung, Brenda F. Reader, Anita Yenigalla, Liwen Zhang, John P. Shapiro, Jon Wisler, John W. Christman, Krishnarao Maddipati, Narasimham L. Parinandi, Manjula Karpurapu

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Targeting ETosis by miR-155 inhibition mitigates mixed granulocytic asthmatic lung inflammation by Ji Young Kim, Ji Young Kim, Patrick Stevens, Manjula Karpurapu, Hyunwook Lee, Joshua A. Englert, Pearlly Yan, Tae Jin Lee, Navjot Pabla, Maciej Pietrzak, Gye Young Park, John W. Christman, Sangwoon Chung

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Nanoparticle delivery of microRNA-146a regulates mechanotransduction in lung macrophages and mitigates injury during mechanical ventilation by Christopher M. Bobba, Qinqin Fei, Vasudha Shukla, Hyunwook Lee, Pragi Patel, Rachel K. Putman, Carleen Spitzer, MuChun Tsai, Mark D. Wewers, Robert J. Lee, John W. Christman, Megan N. Ballinger, Samir N. Ghadiali, Joshua A. Englert

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NADPH oxidase limits innate immune responses in the lungs in mice. by Brahm H Segal, Wei Han, Jennifer J Bushey, Myungsoo Joo, Zahida Bhatti, Joy Feminella, Carly G Dennis, R Robert Vethanayagam, Fiona E Yull, Maegan Capitano, Paul K Wallace, Hans Minderman, John W Christman, Michael B Sporn, Jefferson Chan, Donald C Vinh, Steven M Holland, Luigina R Romani, Sarah L Gaffen, Michael L Freeman, Timothy S Blackwell

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A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury by Ji Young Kim, Yuntao Bai, Laura A. Jayne, Ralph D. Hector, Avinash K. Persaud, Su Sien Ong, Shreshtha Rojesh, Radhika Raj, Mei Ji He Ho Feng, Sangwoon Chung, Rachel E. Cianciolo, John W. Christman, Moray J. Campbell, David S. Gardner, Sharyn D. Baker, Alex Sparreboom, Rajgopal Govindarajan, Harpreet Singh, Taosheng Chen, Ming Poi, Katalin Susztak, Stuart R. Cobb, Navjot Singh Pabla

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mTORC1 is a mechanosensor that regulates surfactant function and lung compliance during ventilator-induced lung injury by Hyunwook Lee, Qinqin Fei, Adam Streicher, Wenjuan Zhang, Colleen Isabelle, Pragi Patel, Hilaire C. Lam, Antonio Arciniegas-Rubio, Miguel Pinilla-Vera, Diana P. Amador-Munoz, Diana Barragan-Bradford, Angelica Higuera-Moreno, Rachel K. Putman, Lynette M. Sholl, Elizabeth P. Henske, Christopher M. Bobba, Natalia Higuita-Castro, Emily M. Shalosky, R. Duncan Hite, John W. Christman, Samir N. Ghadiali, Rebecca M. Baron, Joshua A. Englert

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