Editorial: Interplay Between Autophagy and Metabolic Syndrome: Causes, Consequences and Therapeutic Challenges by Stephen F. Rodrigues, Karen Y. Stokes, William T. Festuccia, Joilson O. Martins

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Insights into the regulation of TNF-a production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition by Jessica Deree, Joilson O. Martins, Heidi Melbostad, William H. Loomis, Raul Coimbra

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Insulin Modulates Cytokine Release, Collagen and Mucus Secretion in Lung Remodeling of Allergic Diabetic Mice by Sabrina S. Ferreira, Fernanda P. B. Nunes, Felipe B. Casagrande, Joilson O. Martins

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Insulin Influences LPS-Induced TNF-α and IL-6 Release Through Distinct Pathways in Mouse Macrophages from Different Compartments by Fernando H. G. Tessaro, Thais S. Ayala, Eduardo L. Nolasco, Leonardo M. Bella, Joilson O. Martins

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Evaluation of the effects of ozone therapy in the treatment of intra-abdominal infection in rats by Yglesio Moyses de Souza, Belchor Fontes, Joilson O Martins, Paulina Sannomiya, Glacus S. Brito, Riad N. Younes, Samir Rasslan

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Sepsis-induced acute lung injury (ALI) is milder in diabetic rats and correlates with impaired NFkB activation. by Luciano R Filgueiras, Joilson O Martins, Carlos H Serezani, Vera L Capelozzi, Marlise B A Montes, Sonia Jancar

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Insulin Influences Autophagy Response Distinctively in Macrophages of Different Compartments by Karen K. S. Sunahara, Fernanda P. B. Nunes, Marisa A. P. Baptista, Carina Strell, Paulina Sannomiya, Lisa S. Westerberg, Joilson O. Martins

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The influence of high glucose conditions on macrophages and its effect on the autophagy pathway by Emanuella S. A. Sousa, Luiz A. D. Queiroz, João P. T. Guimarães, Kamilla C. Pantoja, Rafael S. Barros, Sabrina Epiphanio, Joilson O. Martins

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Insulin Modulates Liver Function in a Type I Diabetes Rat Model by Eduardo L. Nolasco, Fernando L. Zanoni, Fernanda P. B. Nunes, Sabrina S. Ferreira, Luiza A. Freitas, Mariana C.F. Silva, Joilson O. Martins

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The role of captopril in leukotriene deficient type 1 diabetic mice by João Pedro Tôrres Guimarães, Luiz A. D. Queiroz, Kalhara R. Menikdiwela, Nayara Pereira, Theresa Ramalho, Sonia Jancar, Naima Moustaid-Moussa, Joilson O. Martins

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Insulin Modulates the Immune Cell Phenotype in Pulmonary Allergic Inflammation and Increases Pulmonary Resistance in Diabetic Mice by Sabrina S. Ferreira, Maria A. Oliveira, Maristela Tsujita, Fernanda P. B. Nunes, Felipe B. Casagrande, Eliane Gomes, Momtchilo Russo, Wothan Tavares de Lima, Joilson O. Martins

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Aedes aegypti saliva impairs M1-associated proinflammatory phenotype without promoting or affecting M2 polarization of murine macrophages by Michele S. Barros, Priscila G. Lara, Monique T. Fonseca, Eduardo H. Moretti, Luciano R. Filgueiras, Joilson O. Martins, Margareth L. Capurro, Alexandre A. Steiner, Anderson Sá-Nunes

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Genetic Deficiency of Indoleamine 2,3-dioxygenase Aggravates Vascular but Not Liver Disease in a Nonalcoholic Steatohepatitis and Atherosclerosis Comorbidity Model by Aastha Arora, Gustavo Luis Tripodi, Ilona Kareinen, Martin Berg, Maria Josefa Forteza, Anton Gisterå, Silke Griepke, Felipe Beccaria Casagrande, Joilson O. Martins, Dulcineia Saes Parra Abdalla, Jennifer Cole, Claudia Monaco, Daniel F. J. Ketelhuth

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Effects of low-dose rapamycin on lymphoid organs of mice prone and resistant to accelerated senescence by Rafael dos Santos Barros, Luiz Adriano Damasceno Queiroz, Josiane Betim de Assis, Kamilla Costa Pantoja, Sofia Xavier Bustia, Emanuella Sarmento Alho de Sousa, Stephen Fernandes Rodrigues, Eliana Hiromi Akamine, Anderson Sá-Nunes, Joilson O. Martins

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Insulin Modulates Inflammatory Cytokine Release in Acute Stages and Augments Expression of Adhesion Molecules and Leukocytes in Lungs on Chronic Stages of Paracoccidioidomycosis by Felipe Beccaria Casagrande, Sabrina de Souza Ferreira, Emanuella Sarmento Alho de Sousa, João Pedro Tôrres Guimarães, Lavínia Maria Dal’Mas Romera, Fernando Henrique Galvão Tessaro, Sandro Rogério de Almeida, Stephen Fernandes de Paula Rodrigues, Joilson O. Martins

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Cytokine and Adhesion Molecule Expression Induced by Different Strains of Staphylococcus aureus in Type 1 Diabetic Rats: Role of Insulin by Paula R. Knox de Souza, Paula R. Knox de Souza, Sabrina S. Ferreira, Fernanda P. B. Nunes, Felipe B. Casagrande, Fernando H. G. Tessaro, Mariana C. F. Silva, José Walber Miranda Costa Cruz, Elsa M. Mamizuka, Joilson O. Martins

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