Environmental Factors Contribute to β Cell Endoplasmic Reticulum Stress and Neo-Antigen Formation in Type 1 Diabetes Por Meghan L. Marré, Jon D. Piganelli

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Oxidative Stress and Redox Modulation Potential in Type 1 Diabetes Por Meghan M. Delmastro, Jon D. Piganelli

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Decoding the immune dance: Unraveling the interplay between beta cells and type 1 diabetes Por Saptarshi Roy, Pravil Pokharel, Jon D. Piganelli

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An orally available cancer drug AZD6738 prevents type 1 diabetes Por Norie Sugitani, Norie Sugitani, Norie Sugitani, Hannah R. Mason, Brian T. Campfield, Brian T. Campfield, Jon D. Piganelli, Jon D. Piganelli

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β cell ER stress and the implications for immunogenicity in type 1 diabetes Por Meghan L. Marre, Eddie A. James, Jon D. Piganelli

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TRI microparticles prevent inflammatory arthritis in a collagen-induced arthritis model. Por Ethan J Bassin, Abigail R Buckley, Jon D Piganelli, Steven R Little

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Hepatocyte growth factor modulates interleukin-6 production in bone marrow derived macrophages: implications for inflammatory mediated diseases. Por Gina M Coudriet, Jing He, Massimo Trucco, Wendy M Mars, Jon D Piganelli

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Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity Por Matthew C. Austin, Charanya Muralidharan, Saptarshi Roy, Justin J. Crowder, Jon D. Piganelli, Amelia K. Linnemann, Amelia K. Linnemann

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Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4+ T cell activation. Por Dana M Previte, Erin C O'Connor, Elizabeth A Novak, Christina P Martins, Kevin P Mollen, Jon D Piganelli

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Epithelial NAD+ depletion drives mitochondrial dysfunction and contributes to intestinal inflammation Por Elizabeth A. Novak, Elizabeth A. Novak, Erin C. Crawford, Heather L. Mentrup, Heather L. Mentrup, Brian D. Griffith, David M. Fletcher, Meredith R. Flanagan, Corinne Schneider, Corinne Schneider, Brian Firek, Brian Firek, Matthew B. Rogers, Matthew B. Rogers, Michael J. Morowitz, Michael J. Morowitz, Jon D. Piganelli, Jon D. Piganelli, Qian Wang, Kevin P. Mollen, Kevin P. Mollen

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T Cell Receptor-Independent, CD31/IL-17A-Driven Inflammatory Axis Shapes Synovitis in Juvenile Idiopathic Arthritis Por Ian D. Ferguson, Ian D. Ferguson, Patricia Griffin, Joshua J. Michel, Joshua J. Michel, Hiroshi Yano, Sarah L. Gaffen, Sarah L. Gaffen, Robert G. Mueller, Robert G. Mueller, Jeffrey A. Dvergsten, Jon D. Piganelli, Jon D. Piganelli, Margalit E. Rosenkranz, Margalit E. Rosenkranz, Daniel A. Kietz, Daniel A. Kietz, Abbe N. Vallejo, Abbe N. Vallejo, Abbe N. Vallejo

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Glycolysis Inhibition Induces Functional and Metabolic Exhaustion of CD4+ T Cells in Type 1 Diabetes Por Christina P. Martins, Christina P. Martins, Lee A. New, Erin C. O’Connor, Dana M. Previte, Kasey R. Cargill, Isabelle L. Tse, Sunder Sims- Lucas, Jon D. Piganelli

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Treatment with a Catalytic Superoxide Dismutase (SOD) Mimetic Improves Liver Steatosis, Insulin Sensitivity, and Inflammation in Obesity-Induced Type 2 Diabetes Por Gina M. Coudriet, Meghan M. Delmastro-Greenwood, Dana M. Previte, Meghan L. Marré, Erin C. O’Connor, Elizabeth A. Novak, Garret Vincent, Kevin P. Mollen, Sojin Lee, H. Henry Dong, Jon D. Piganelli

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Lymphocyte Activation Gene-3 Maintains Mitochondrial and Metabolic Quiescence in Naive CD4+ T Cells Por Dana M. Previte, Christina P. Martins, Erin C. O’Connor, Meghan L. Marre, Gina M. Coudriet, Noah W. Beck, Ashley V. Menk, Rebecca H. Wright, Hubert M. Tse, Greg M. Delgoffe, Jon D. Piganelli

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Acinar to β-like cell conversion through inhibition of focal adhesion kinase Por Shakti Dahiya, Mohamed Saleh, Uylissa A. Rodriguez, Dhivyaa Rajasundaram, Jorge R. Arbujas, Arian Hajihassani, Kaiyuan Yang, Anuradha Sehrawat, Ranjeet Kalsi, Shiho Yoshida, Krishna Prasadan, Heiko Lickert, Jing Hu, Jon D. Piganelli, George K. Gittes, Farzad Esni

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Human-Scale Whole-Organ Bioengineering for Liver Transplantation: A Regenerative Medicine Approach Por Hiroshi Yagi, Ken Fukumitsu, Kazumasa Fukuda, Minoru Kitago, Masahiro Shinoda, Hideaki Obara, Osamu Itano, Shigeyuki Kawachi, Minoru Tanabe, Gina M. Coudriet, Jon D. Piganelli, Thomas W. Gilbert, Alejandro Soto-Gutierrez M.D., Ph.D., Yuko Kitagawa M.D., Ph.D., FACS

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