Quantifying type-specific reproduction numbers for nosocomial pathogens: evidence for heightened transmission of an Asian sequence type 239 MRSA clone. by Ben S Cooper, Theodore Kypraios, Rahul Batra, Duncan Wyncoll, Olga Tosas, Jonathan D Edgeworth

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COVID-19: stewardship of diagnostic tests for bacterial co-infection by Tom G S Williams, Luke B Snell, Jonathan D Edgeworth, Geraldine A O'Hara

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Genetic Diversity of norA, Coding for a Main Efflux Pump of Staphylococcus aureus by Sofia Santos Costa, Benjamin Sobkowiak, Ricardo Parreira, Jonathan D. Edgeworth, Miguel Viveiros, Taane G. Clark, Taane G. Clark, Isabel Couto

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Real-world effectiveness of steroids in severe COVID-19: a retrospective cohort study by Wenjuan Wang, Luke B Snell, Davide Ferrari, Anna L Goodman, Nicholas M Price, Charles D Wolfe, Vasa Curcin, Jonathan D Edgeworth, Yanzhong Wang

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The first reported case of human infection with Variovorax durovernensis; a novel Variovorax sp. Isolated from the prosthetic aortic graft of a shepherd by Lara Payne, Adela Alcolea-Medina, Luke B Snell, Christopher Alder, Themoula Charalampous, Jake D Turnbull, Jonathan D Edgeworth, Rahul Batra, John L Klein, Anna L Goodman

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Broad Neutralization of SARS-CoV-2 Variants, Including Omicron, following Breakthrough Infection with Delta in COVID-19-Vaccinated Individuals by Thomas Lechmere, Luke B. Snell, Carl Graham, Jeffrey Seow, Zayed A. Shalim, Themoula Charalampous, Adela Alcolea-Medina, Rahul Batra, Gaia Nebbia, Jonathan D. Edgeworth, Michael H. Malim, Katie J. Doores

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Publisher Correction: Unified metagenomic method for rapid detection of microorganisms in clinical samples by Adela Alcolea-Medina, Christopher Alder, Luke B. Snell, Themoula Charalampous, Alp Aydin, Gaia Nebbia, Tom Williams, Simon Goldenberg, Sam Douthwaite, Rahul Batra, Penelope R. Cliff, Hannah Mischo, Stuart Neil, Mark Wilks, Jonathan D. Edgeworth

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Unified metagenomic method for rapid detection of microorganisms in clinical samples by Adela Alcolea-Medina, Christopher Alder, Luke B. Snell, Themoula Charalampous, Alp Aydin, Gaia Nebbia, Tom Williams, Simon Goldenberg, Sam Douthwaite, Rahul Batra, Penelope R. Cliff, Hannah Mischo, Stuart Neil, Mark Wilks, Jonathan D. Edgeworth

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Evidence for Community Transmission of Community-Associated but Not Health-Care-Associated Methicillin-Resistant Staphylococcus Aureus Strains Linked to Social and Material Depriva... by Olga Tosas Auguet, Jason R Betley, Richard A Stabler, Amita Patel, Avgousta Ioannou, Helene Marbach, Pasco Hearn, Anna Aryee, Simon D Goldenberg, Jonathan A Otter, Nergish Desai, Tacim Karadag, Chris Grundy, Michael W Gaunt, Ben S Cooper, Jonathan D Edgeworth, Theodore Kypraios

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Translational Research in the Time of COVID-19-Dissolving Boundaries. by Jonathan D Edgeworth, Rahul Batra, Gaia Nebbia, Karen Bisnauthsing, Eithne MacMahon, Malur Sudhanva, Sam Douthwaite, Simon Goldenberg, Geraldine O'Hara, Manu Shankar-Hari, Katie J Doores, Rocio Martinez-Nunez, Carolyn Hemsley, Nicholas M Price, Jill Lockett, Robert I Lechler, Stuart J D Neil, Michael H Malim

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Translational Research in the Time of COVID-19—Dissolving Boundaries by Jonathan D. Edgeworth, Rahul Batra, Gaia Nebbia, Karen Bisnauthsing, Eithne MacMahon, Malur Sudhanva, Sam Douthwaite, Simon Goldenberg, Geraldine O’Hara, Manu Shankar-Hari, Katie J. Doores, Rocio Martinez-Nunez, Carolyn Hemsley, Nicholas M. Price, Jill Lockett, Robert I. Lechler, Stuart J. D. Neil, Michael H. Malim, Carolyn B. Coyne

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Clinical utility of targeted SARS-CoV-2 serology testing to aid the diagnosis and management of suspected missed, late or post-COVID-19 infection syndromes: Results from a pilot se... by Nicola Sweeney, Blair Merrick, Rui Pedro Galão, Suzanne Pickering, Alina Botgros, Harry D Wilson, Adrian W Signell, Gilberto Betancor, Mark Kia Ik Tan, John Ramble, Neophytos Kouphou, Sam Acors, Carl Graham, Jeffrey Seow, Eithne MacMahon, Stuart J D Neil, Michael H Malim, Katie Doores, Sam Douthwaite, Rahul Batra, Gaia Nebbia, Jonathan D Edgeworth

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Evaluating the potential for respiratory metagenomics to improve treatment of secondary infection and detection of nosocomial transmission on expanded COVID-19 intensive care units by Themoula Charalampous, Adela Alcolea-Medina, Luke B. Snell, Tom G. S. Williams, Rahul Batra, Christopher Alder, Andrea Telatin, Luigi Camporota, Christopher I. S. Meadows, Duncan Wyncoll, Nicholas A. Barrett, Carolyn J. Hemsley, Lisa Bryan, William Newsholme, Sara E. Boyd, Anna Green, Ula Mahadeva, Amita Patel, Penelope R. Cliff, Andrew J. Page, Justin O’Grady, Jonathan D. Edgeworth

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Therapeutic antibodies, targeting the SARS-CoV-2 spike N-terminal domain, protect lethally infected K18-hACE2 mice by Tal Noy-Porat, Adva Mechaly, Yinon Levy, Efi Makdasi, Ron Alcalay, David Gur, Moshe Aftalion, Reut Falach, Shani Leviatan Ben-Arye, Shirley Lazar, Ayelet Zauberman, Eyal Epstein, Theodor Chitlaru, Shay Weiss, Hagit Achdout, Jonathan D. Edgeworth, Raghavendra Kikkeri, Hai Yu, Xi Chen, Shmuel Yitzhaki, Shmuel C. Shapira, Vered Padler-Karavani, Ohad Mazor, Ronit Rosenfeld

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SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies by Ceri Alan Fielding, Pragati Sabberwal, James C Williamson, Edward JD Greenwood, Thomas WM Crozier, Wioleta Zelek, Jeffrey Seow, Carl Graham, Isabella Huettner, Jonathan D Edgeworth, David A Price, Paul B Morgan, Kristin Ladell, Matthias Eberl, Ian R Humphreys, Blair Merrick, Katie Doores, Sam J Wilson, Paul J Lehner, Eddie CY Wang, Richard J Stanton

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Comparative assessment of multiple COVID-19 serological technologies supports continued evaluation of point-of-care lateral flow assays in hospital and community healthcare setting... by Suzanne Pickering, Gilberto Betancor, Rui Pedro Galão, Blair Merrick, Adrian W Signell, Harry D Wilson, Mark Tan Kia Ik, Jeffrey Seow, Carl Graham, Sam Acors, Neophytos Kouphou, Kathryn J A Steel, Oliver Hemmings, Amita Patel, Gaia Nebbia, Sam Douthwaite, Lorcan O'Connell, Jakub Luptak, Laura E McCoy, Philip Brouwer, Marit J van Gils, Rogier W Sanders, Rocio Martinez Nunez, Karen Bisnauthsing, Geraldine O'Hara, Eithne MacMahon, Rahul Batra, Michael H Malim, Stuart J D Neil, Katie J Doores, Jonathan D Edgeworth

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Comparative performance of SARS-CoV-2 lateral flow antigen tests and association with detection of infectious virus in clinical specimens: a single-centre laboratory evaluation stu... by Suzanne Pickering, PhD, Rahul Batra, MD, Blair Merrick, MBChB, Luke B Snell, MBBS, Gaia Nebbia, FRCPath, Sam Douthwaite, MRCP, Fiona Reid, MSc, Amita Patel, BSc, Mark Tan Kia Ik, BSc, Bindi Patel, BSc, Themoula Charalampous, PhD, Adela Alcolea-Medina, MPhil, Maria Jose Lista, PhD, Penelope R Cliff, PhD, Emma Cunningham, MSc, Jane Mullen, BSc, Katie J Doores, PhD, Jonathan D Edgeworth, ProfFRCPath, Michael H Malim, ProfDPhil, Stuart J D Neil, ProfPhD, Rui Pedro Galão, PhD

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SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care by Clemens Gutmann, Kaloyan Takov, Sean A. Burnap, Bhawana Singh, Hashim Ali, Konstantinos Theofilatos, Ella Reed, Maria Hasman, Adam Nabeebaccus, Matthew Fish, Mark JW. McPhail, Kevin O’Gallagher, Lukas E. Schmidt, Christian Cassel, Marieke Rienks, Xiaoke Yin, Georg Auzinger, Salvatore Napoli, Salma F. Mujib, Francesca Trovato, Barnaby Sanderson, Blair Merrick, Umar Niazi, Mansoor Saqi, Konstantina Dimitrakopoulou, Rafael Fernández-Leiro, Silke Braun, Romy Kronstein-Wiedemann, Katie J. Doores, Jonathan D. Edgeworth, Ajay M. Shah, Stefan R. Bornstein, Torsten Tonn, Adrian C. Hayday, Mauro Giacca, Manu Shankar-Hari, Manuel Mayr

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Adjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia: the ARREST RCT by Guy E Thwaites, Matthew Scarborough, Alexander Szubert, Pedro Saramago Goncalves, Marta Soares, Jennifer Bostock, Emmanuel Nsutebu, Robert Tilley, Richard Cunningham, Julia Greig, Sarah A Wyllie, Peter Wilson, Cressida Auckland, Janet Cairns, Denise Ward, Pankaj Lal, Achyut Guleri, Neil Jenkins, Julian Sutton, Martin Wiselka, Gonzalez-Ruiz Armando, Clive Graham, Paul R Chadwick, Gavin Barlow, N Claire Gordon, Bernadette Young, Sarah Meisner, Paul McWhinney, David A Price, David Harvey, Deepa Nayar, Dakshika Jeyaratnam, Timothy Planche, Jane Minton, Fleur Hudson, Susan Hopkins, John Williams, M Estee Török, Martin J Llewelyn, Jonathan D Edgeworth, A Sarah Walker

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SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study by Judith Breuer, Catherine F Houlihan, Nick Freemantle, David Partridge, Gaia Nebbia, Jacqui Prieto, Gee Yen Shin, Andrew Copas, Oliver Stirrup, Kenneth Laing, Rachel Williams, Helen Wheeler, Paul Randell, Ana da Silva Filipe, Maria-Teresa Cutino-Moguel, Tommy Rampling, Tabassum Khan, James Price, Eleni Nastouli, Katie Johnson, Sharon Glaysher, Scott Elliott, Helen Umpleby, Emanuela Pelosi, Emma Thomson, Cristina Venturini, Anna Riddell, Alison Cox, Andrew C Hayward, Malin Bergström, David Harrington, Charlotte Williams, Tanzina Haque, Dianne Irish, Adrienn Angyal, Marios Margaritis, Moira Spyer, Florencia Boshier, José Afonso Guerra-Assunção, Adela Alcolea-Medina, Angela Beckett, Themoula Charalampous, Raghavendran Kulasegaran Shylini, Beatrix Kele, Irene Monahan, Guy Mollett, Matthew Parker, Sunando Roy, Joshua Taylor, Sophie Weller, Eleri Wilson-Davies, Phillip Wade, Joseph Hughes, Tabitha Mahungu, Cassie Pope, Samuel Robson, Kordo Saeed, Thushan de Silva, Luke Snell, Adam A Witney, James Blackstone, Leanne Hockey, Georgia Marley, Christine Peters, Flavia Flaviani, Bindi Patel, Tom G S Williams, Rahul Batra, Jonathan D Edgeworth, Pinglawathee Madona, Jennifer Hart, Juanita Pang, Helena Tutill, Nadua Bayzid, Marius Cotic, Luke Green, Benjamin Lindsey, Amy State, Alison Cope, Peijun Zhang, Max Whiteley, Marta Gallis Ramalho, Stella Christou, Stavroula Louka, Hailey Hornsby, Benjamin Foulkes, Paige Wolverson, Joe Heffer, Nikki Smith, Salman Goudarzi, Chris Fearn, Kate Cook, Katie Loveson, Adhyana Mahamana, Buddhini Samaraweera, Siona Silveira, Stephen Aplin, Sarah Jeremiah, Matthew Harvey, Thea Sass, Ngee Keong Tan, Claudia Cardoso Pereira, Dan Frampton, Matt Byott, Judith Heaney, Emilie Sanchez, Stavroula M Paraskevopoulou

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