Using single-nucleus RNA-sequencing to interrogate transcriptomic profiles of archived human pancreatic islets by Giorgio Basile, Sevim Kahraman, Ercument Dirice, Hui Pan, Jonathan M. Dreyfuss, Rohit N. Kulkarni

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Metabolic modeling of muscle metabolism identifies key reactions linked to insulin resistance phenotypes by Christopher Nogiec, Alison Burkart, Jonathan M. Dreyfuss, Carles Lerin, Simon Kasif, Mary-Elizabeth Patti

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Reconstruction and validation of a genome-scale metabolic model for the filamentous fungus Neurospora crassa using FARM. by Jonathan M Dreyfuss, Jeremy D Zucker, Heather M Hood, Linda R Ocasio, Matthew S Sachs, James E Galagan

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Integrating Extracellular Flux Measurements and Genome-Scale Modeling Reveals Differences between Brown and White Adipocytes by Alfred K. Ramirez, Matthew D. Lynes, Farnaz Shamsi, Ruidan Xue, Yu-Hua Tseng, C. Ronald Kahn, Simon Kasif, Jonathan M. Dreyfuss

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Unique ligand and kinase-independent roles of the insulin receptor in regulation of cell cycle, senescence and apoptosis by Hirofumi Nagao, Ashok Kumar Jayavelu, Weikang Cai, Hui Pan, Jonathan M. Dreyfuss, Thiago M. Batista, Bruna B. Brandão, Matthias Mann, C. Ronald Kahn

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FoxK1 associated gene regulatory network in hepatic insulin action and its relationship to FoxO1 and insulin receptor mediated transcriptional regulation by Prasanna K.R. Allu, Maria Dafne Cardamone, Antonio S. Gomes, Alessandra Dall'agnese, Carly Cederquist, Hui Pan, Jonathan M. Dreyfuss, Sven Enerbäck, C. Ronald Kahn

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Transcriptomic Regulation of Muscle Mitochondria and Calcium Signaling by Insulin/IGF-1 Receptors Depends on FoxO Transcription Factors by Gourav Bhardwaj, Christie M. Penniman, Katherine Klaus, Eric T. Weatherford, Hui Pan, Jonathan M. Dreyfuss, K. Sreekumaran Nair, C. Ronald Kahn, Brian T. O’Neill, Brian T. O’Neill

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Unphosphorylated SR-like protein Npl3 stimulates RNA polymerase II elongation. by Jessica L Dermody, Jonathan M Dreyfuss, Judit Villén, Babatunde Ogundipe, Steven P Gygi, Peter J Park, Alfred S Ponticelli, Claire L Moore, Stephen Buratowski, Miriam E Bucheli

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Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites by Shiho Fujisaka, Julian Avila-Pacheco, Marion Soto, Aleksandar Kostic, Jonathan M. Dreyfuss, Hui Pan, Siegfried Ussar, Emrah Altindis, Ning Li, Lynn Bry, Clary B. Clish, C. Ronald Kahn

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Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence by Michael J Steinbaugh, Sri Devi Narasimhan, Stacey Robida-Stubbs, Lorenza E Moronetti Mazzeo, Jonathan M Dreyfuss, John M Hourihan, Prashant Raghavan, Theresa N Operaña, Reza Esmaillie, T Keith Blackwell

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Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling by Hirofumi Nagao, Weikang Cai, Bruna B. Brandão, Nicolai J. Wewer Albrechtsen, Martin Steger, Arijeet K. Gattu, Hui Pan, Jonathan M. Dreyfuss, F. Thomas Wunderlich, Matthias Mann, C. Ronald Kahn

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The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response by Sydney Lavoie, Kara L Conway, Kara G Lassen, Humberto B Jijon, Hui Pan, Eunyoung Chun, Monia Michaud, Jessica K Lang, Carey Ann Gallini Comeau, Jonathan M Dreyfuss, Jonathan N Glickman, Hera Vlamakis, Ashwin Ananthakrishnan, Aleksander Kostic, Wendy S Garrett, Ramnik J Xavier

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E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance by Jun Shirakawa, Yu Togashi, Giorgio Basile, Tomoko Okuyama, Ryota Inoue, Megan Fernandez, Mayu Kyohara, Dario F. De Jesus, Nozomi Goto, Wei Zhang, Takahiro Tsuno, Tatsuya Kin, Hui Pan, Jonathan M. Dreyfuss, A.M. James Shapiro, Peng Yi, Yasuo Terauchi, Rohit N. Kulkarni

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Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism by Carles Lerin, Allison B. Goldfine, Tanner Boes, Manway Liu, Simon Kasif, Jonathan M. Dreyfuss, Ana Luisa De Sousa-Coelho, Grace Daher, Irini Manoli, Justin R. Sysol, Elvira Isganaitis, Niels Jessen, Laurie J. Goodyear, Kirk Beebe, Walt Gall, Charles P. Venditti, Mary-Elizabeth Patti

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High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control by Jonathan M. Dreyfuss, Yixing Yuchi, Xuehong Dong, Vissarion Efthymiou, Hui Pan, Donald C. Simonson, Ashley Vernon, Florencia Halperin, Pratik Aryal, Anish Konkar, Yinong Sebastian, Brandon W. Higgs, Joseph Grimsby, Cristina M. Rondinone, Simon Kasif, Barbara B. Kahn, Kathleen Foster, Randy Seeley, Allison Goldfine, Vera Djordjilović, Mary Elizabeth Patti

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