Showing 1 - 16 results of 16 for search 'Jonathan R. Dry', 查询时间: 0.07s Refine Results
  1. 1
    Looking beyond the cancer cell for effective drug combinations

    Looking beyond the cancer cell for effective drug combinations 由 Jonathan R. Dry, Mi Yang, Julio Saez-Rodriguez

    出版 2016-11-01
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  2. 2
    DeePaN: deep patient graph convolutional network integrating clinico-genomic evidence to stratify lung cancers for immunotherapy

    DeePaN: deep patient graph convolutional network integrating clinico-genomic evidence to stratify lung cancers for immunotherapy 由 Chao Fang, Dong Xu, Jing Su, Jonathan R Dry, Bolan Linghu

    出版 2021-02-01
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  3. 3
    Landscape of homologous recombination deficiencies in solid tumours: analyses of two independent genomic datasets

    Landscape of homologous recombination deficiencies in solid tumours: analyses of two independent genomic datasets 由 Zhongwu Lai, Matthew Brosnan, Ethan S. Sokol, Mingchao Xie, Jonathan R. Dry, Elizabeth A. Harrington, J. Carl Barrett, Darren Hodgson

    出版 2022-01-01
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  4. 4
    Identification of Intrinsic Drug Resistance and Its Biomarkers in High-Throughput Pharmacogenomic and CRISPR Screens

    Identification of Intrinsic Drug Resistance and Its Biomarkers in High-Throughput Pharmacogenomic and CRISPR Screens 由 Iñigo Ayestaran, Ana Galhoz, Elmar Spiegel, Ben Sidders, Jonathan R. Dry, Frank Dondelinger, Andreas Bender, Ultan McDermott, Francesco Iorio, Michael P. Menden

    出版 2020-08-01
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  5. 5
    A statistical framework for assessing pharmacological responses and biomarkers using uncertainty estimates

    A statistical framework for assessing pharmacological responses and biomarkers using uncertainty estimates 由 Dennis Wang, James Hensman, Ginte Kutkaite, Tzen S Toh, Ana Galhoz, GDSC Screening Team, Jonathan R Dry, Julio Saez-Rodriguez, Mathew J Garnett, Michael P Menden, Frank Dondelinger

    出版 2020-12-01
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  6. 6
    Validation of genomic and transcriptomic models of homologous recombination deficiency in a real-world pan-cancer cohort

    Validation of genomic and transcriptomic models of homologous recombination deficiency in a real-world pan-cancer cohort 由 Benjamin D. Leibowitz, Bonnie V. Dougherty, Joshua S. K. Bell, Joshuah Kapilivsky, Jackson Michuda, Andrew J. Sedgewick, Wesley A. Munson, Tushar A. Chandra, Jonathan R. Dry, Nike Beaubier, Catherine Igartua, Timothy Taxter

    出版 2022-05-01
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  7. 7
    620 Multimodal real world data reveals immunogenomic drivers of acquired and primary resistance to immune checkpoint blockade

    620 Multimodal real world data reveals immunogenomic drivers of acquired and primary resistance to immune checkpoint blockade 由 Ross Stewart, Mark Cobbold, Scott Hammond, Sajan Khosla, Roy Rabbie, Douglas C Palmer, Mohamed Reda Keddar, Sebastian Carrasco Pro, Kathleen Burke, Ana Stewart, Benjamin Sidders, Jonathan R Dry, Martin L Miller

    出版 2023-11-01
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  8. 8
    Author Correction: Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors

    Author Correction: Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors 由 Orsolya Papp, Viktória Jordán, Szabolcs Hetey, Róbert Balázs, Valér Kaszás, Árpád Bartha, Nóra N. Ordasi, Sebestyén Kamp, Bálint Farkas, Jerome Mettetal, Jonathan R. Dry, Duncan Young, Ben Sidders, Krishna C. Bulusu, Daniel V. Veres

    出版 2024-08-01
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  9. 9
    Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors

    Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors 由 Orsolya Papp, Viktória Jordán, Szabolcs Hetey, Róbert Balázs, Valér Kaszás, Árpád Bartha, Nóra N. Ordasi, Sebestyén Kamp, Bálint Farkas, Jerome Mettetal, Jonathan R. Dry, Duncan Young, Ben Sidders, Krishna C. Bulusu, Daniel V. Veres

    出版 2024-06-01
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  10. 10
    Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer

    Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer 由 Anna Gogleva, Dimitris Polychronopoulos, Matthias Pfeifer, Vladimir Poroshin, Michaël Ughetto, Matthew J. Martin, Hannah Thorpe, Aurelie Bornot, Paul D. Smith, Ben Sidders, Jonathan R. Dry, Miika Ahdesmäki, Ultan McDermott, Eliseo Papa, Krishna C. Bulusu

    出版 2022-03-01
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  11. 11
    Targeting melanoma’s MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors

    Targeting melanoma’s MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors 由 Matthew J. Sale, Emma Minihane, Noel R. Monks, Rebecca Gilley, Frances M. Richards, Kevin P. Schifferli, Courtney L. Andersen, Emma J. Davies, Mario Aladren Vicente, Eiko Ozono, Aleksandra Markovets, Jonathan R. Dry, Lisa Drew, Vikki Flemington, Theresa Proia, Duncan I. Jodrell, Paul D. Smith, Simon J. Cook

    出版 2019-11-01
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  12. 12
    MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance

    MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance 由 Matthew J. Sale, Kathryn Balmanno, Jayeta Saxena, Eiko Ozono, Katarzyna Wojdyla, Rebecca E. McIntyre, Rebecca Gilley, Anna Woroniuk, Karen D. Howarth, Gareth Hughes, Jonathan R. Dry, Mark J. Arends, Pilar Caro, David Oxley, Susan Ashton, David J. Adams, Julio Saez-Rodriguez, Paul D. Smith, Simon J. Cook

    出版 2019-05-01
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  13. 13
    The landscape of therapeutic vulnerabilities in EGFR inhibitor osimertinib drug tolerant persister cells

    The landscape of therapeutic vulnerabilities in EGFR inhibitor osimertinib drug tolerant persister cells 由 Steven W. Criscione, Matthew J. Martin, Derek B. Oien, Aparna Gorthi, Ricardo J. Miragaia, Jingwen Zhang, Huawei Chen, Daniel L. Karl, Kerrin Mendler, Aleksandra Markovets, Sladjana Gagrica, Oona Delpuech, Jonathan R. Dry, Michael Grondine, Maureen M. Hattersley, Jelena Urosevic, Nicolas Floc’h, Lisa Drew, Yi Yao, Paul D. Smith

    出版 2022-12-01
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  14. 14
    Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

    Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen 由 Michael P. Menden, Dennis Wang, Mike J. Mason, Bence Szalai, Krishna C. Bulusu, Yuanfang Guan, Thomas Yu, Jaewoo Kang, Minji Jeon, Russ Wolfinger, Tin Nguyen, Mikhail Zaslavskiy, AstraZeneca-Sanger Drug Combination DREAM Consortium, In Sock Jang, Zara Ghazoui, Mehmet Eren Ahsen, Robert Vogel, Elias Chaibub Neto, Thea Norman, Eric K. Y. Tang, Mathew J. Garnett, Giovanni Y. Di Veroli, Stephen Fawell, Gustavo Stolovitzky, Justin Guinney, Jonathan R. Dry, Julio Saez-Rodriguez

    出版 2019-06-01
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  15. 15
    A pan-cancer organoid platform for precision medicine

    A pan-cancer organoid platform for precision medicine 由 Brian M. Larsen, Madhavi Kannan, Lee F. Langer, Benjamin D. Leibowitz, Aicha Bentaieb, Andrea Cancino, Igor Dolgalev, Bridgette E. Drummond, Jonathan R. Dry, Chi-Sing Ho, Gaurav Khullar, Benjamin A. Krantz, Brandon Mapes, Kelly E. McKinnon, Jessica Metti, Jason F. Perera, Tim A. Rand, Veronica Sanchez-Freire, Jenna M. Shaxted, Michelle M. Stein, Michael A. Streit, Yi-Hung Carol Tan, Yilin Zhang, Ende Zhao, Jagadish Venkataraman, Martin C. Stumpe, Jeffrey A. Borgia, Ashiq Masood, Daniel V.T. Catenacci, Jeremy V. Mathews, Demirkan B. Gursel, Jian-Jun Wei, Theodore H. Welling, Diane M. Simeone, Kevin P. White, Aly A. Khan, Catherine Igartua, Ameen A. Salahudeen

    出版 2021-07-01
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  16. 16
    Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling

    Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling 由 Sebastijan Hobor, Maise Al Bakir, Crispin T. Hiley, Marcin Skrzypski, Alexander M. Frankell, Bjorn Bakker, Thomas B. K. Watkins, Aleksandra Markovets, Jonathan R. Dry, Andrew P. Brown, Jasper van der Aart, Hilda van den Bos, Diana Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H. Rabinowitz, Laila Ait Hassou, Saskia Litière, D. Lucas Kerr, Lisa Tan, Gavin Kelly, David A. Moore, Matthew J. Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R. M. Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M. Blakely, Elza C. de Bruin, Floris Foijer, Karen H. Vousden, Trever G. Bivona, TRACERx consortium, Robert E. Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton

    出版 2024-06-01
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