Insulin C-peptide secretion on-a-chip to measure the dynamics of secretion and metabolism from individual islets by Yufeng Wang, Romario Regeenes, Mahnoor Memon, Jonathan V. Rocheleau

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Islet-on-a-chip device reveals first phase glucose-stimulated respiration is substrate limited by glycolysis independent of Ca2+ activity. by Romario Regeenes, Yufeng Wang, Anthony Piro, Aaron Au, Christopher M. Yip, Michael B. Wheeler, Jonathan V. Rocheleau

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Measuring the rate of NADPH consumption by glutathione reductase in the cytosol and mitochondria. by Kenneth K Y Ting, Eric Floro, Riley Dow, Jenny Jongstra-Bilen, Myron I Cybulsky, Jonathan V Rocheleau

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Intracellular accumulation of free cholesterol in macrophages triggers a PARP1 response to DNA damage and PARP1 impairs lipopolysaccharide-induced inflammatory response. by Kenneth K Y Ting, Hisham M Ibrahim, Nitya Gulati, Yufeng Wang, Jonathan V Rocheleau, Myron I Cybulsky

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Increased pressure alters plasma membrane dynamics and renders acute myeloid leukemia cells resistant to daunorubicin by Victor Sanjit Nirmalanandhan, Rose Hurren, William D. Cameron, Marcela Gronda, Aisha Shamas-Din, Lidan You, Mark D. Minden, Jonathan V. Rocheleau, Aaron D Schimmer

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