Understanding blood development and leukemia using sequencing-based technologies and human cell systems by Branco M. H. Heuts, Joost H. A. Martens

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Recent insights into Histone Acetyltransferase-1: biological function and involvement in pathogenesis by Angelita Poziello, Angela Nebbioso, Hendrik G. Stunnenberg, Joost H.A. Martens, Vincenzo Carafa, Lucia Altucci

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The Role of Necroptosis: Biological Relevance and Its Involvement in Cancer by Laura Della Torre, Angela Nebbioso, Hendrik G. Stunnenberg, Joost H. A. Martens, Vincenzo Carafa, Lucia Altucci

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BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells. by Marco Carretta, Annet Z Brouwers-Vos, Matthieu Bosman, Sarah J Horton, Joost H A Martens, Edo Vellenga, Jan Jacob Schuringa

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CBFβ-SMMHC Affects Genome-wide Polycomb Repressive Complex 1 Activity in Acute Myeloid Leukemia by Gaëlle Cordonnier, Amit Mandoli, Nicolas Cagnard, Guillaume Hypolite, Ludovic Lhermitte, Els Verhoeyen, Vahid Asnafi, Niall Dillon, Elizabeth Macintyre, Joost H.A. Martens, Jonathan Bond

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P455: RUNX1 DIRECTLY BINDS AND REGULATES THE TCF4 PROMOTER by Mylene Gerritsen, Florentien E.M. in ‘t Hout, Ruth G.H.J.N. Knops, Bert A. van der Reijden, Joost H.A. Martens, Joop H Jansen

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Inducible MLL-AF9 Expression Drives an AML Program during Human Pluripotent Stem Cell-Derived Hematopoietic Differentiation by Branco M. H. Heuts, Saioa Arza-Apalategi, Sinne G. Alkema, Esther Tijchon, Laura Jussen, Saskia M. Bergevoet, Bert A. van der Reijden, Joost H. A. Martens

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scANANSE gene regulatory network and motif analysis of single-cell clusters [version 2; peer review: 2 approved] by Julian A. Arts, Siebren Frölich, Jos G.A. Smits, Huiqing Zhou, Joost H.A. Martens, Simon J. van Heeringen, Rebecca R. Snabel, Branco M.H. Heuts

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Direct targeted therapy for MLL‐fusion‐driven high‐risk acute leukaemias by Sandra Cantilena, Luca Gasparoli, Deepali Pal, Olaf Heidenreich, Jan‐Henning Klusmann, Joost H. A. Martens, Alexandre Faille, Alan J. Warren, Mawar Karsa, Ruby Pandher, Klaartje Somers, Owen Williams, Jasper de Boer

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HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells by Albertus T. J. Wierenga, Alan Cunningham, Ayşegül Erdem, Nuria Vilaplana Lopera, Annet Z. Brouwers-Vos, Maurien Pruis, André B. Mulder, Ulrich L. Günther, Joost H. A. Martens, Edo Vellenga, Jan Jacob Schuringa

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The acute myeloid leukemia associated AML1-ETO fusion protein alters the transcriptome and cellular progression in a single-oncogene expressing in vitro induced pluripotent stem ce... by Esther Tijchon, Guoqiang Yi, Amit Mandoli, Jos G A Smits, Francesco Ferrari, Branco M H Heuts, Falco Wijnen, Bowon Kim, Eva M Janssen-Megens, Jan Jacob Schuringa, Joost H A Martens

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GFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation by Jeron Venhuizen, Maaike G. J. M. van Bergen, Saskia M. Bergevoet, Daan Gilissen, Cornelia G. Spruijt, Laura Wingens, Emile van den Akker, Michiel Vermeulen, Joop H. Jansen, Joost H. A. Martens, Bert A. van der Reijden

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Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability by Jason P. Wray, Elitza M. Deltcheva, Charlotta Boiers, Simon Е Richardson, Jyoti Bikram Chhetri, John Brown, Sladjana Gagrica, Yanping Guo, Anuradha Illendula, Joost H. A. Martens, Hendrik G. Stunnenberg, John H. Bushweller, Rachael Nimmo, Tariq Enver

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CBX2 shapes chromatin accessibility promoting AML via p38 MAPK signaling pathway by Nunzio Del Gaudio, Antonella Di Costanzo, Ning Qing Liu, Lidio Conte, Carmela Dell’Aversana, Guglielmo Bove, Rosaria Benedetti, Liliana Montella, Fortunato Ciardiello, Vincenzo Carafa, Concetta Ambrosino, Valeria Tucci, Mariarosaria Conte, Joost H. A. Martens, Hendrik G. Stunnenberg, Angela Nebbioso, Lucia Altucci

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Saponin-based adjuvants enhance antigen cross-presentation in human CD11c+ CD1c+ CD5− CD163+ conventional type 2 dendritic cells by Harry Dolstra, Gosse J Adema, Nataschja I Ho, Lisa G M Huis in 't Veld, Jesper van Eck van der Sluijs, Branco M H Heuts, Maaike W G Looman, Esther D Kers-Rebel, Koen van den Dries, Joost H A Martens, Willemijn Hobo

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Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis by Vincent van den Boom, Henny Maat, Marjan Geugien, Aida Rodríguez López, Ana M. Sotoca, Jennifer Jaques, Annet Z. Brouwers-Vos, Fabrizia Fusetti, Richard W.J. Groen, Huipin Yuan, Anton C.M. Martens, Hendrik G. Stunnenberg, Edo Vellenga, Joost H.A. Martens, Jan Jacob Schuringa

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MEIS2 Is an Oncogenic Partner in AML1-ETO-Positive AML by Naidu M. Vegi, Josef Klappacher, Franz Oswald, Medhanie A. Mulaw, Amit Mandoli, Verena N. Thiel, Shiva Bamezai, Kristin Feder, Joost H.A. Martens, Vijay P.S. Rawat, Tamoghna Mandal, Leticia Quintanilla-Martinez, Karsten Spiekermann, Wolfgang Hiddemann, Konstanze Döhner, Hartmut Döhner, Hendrik G. Stunnenberg, Michaela Feuring-Buske, Christian Buske

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Acid ceramidase regulates innate immune memory by Nils Rother, Cansu Yanginlar, Geoffrey Prévot, Inge Jonkman, Maaike Jacobs, Mandy M.T. van Leent, Julia van Heck, Vasiliki Matzaraki, Anthony Azzun, Judit Morla-Folch, Anna Ranzenigo, William Wang, Roy van der Meel, Zahi A. Fayad, Niels P. Riksen, Luuk B. Hilbrands, Rik G.H. Lindeboom, Joost H.A. Martens, Michiel Vermeulen, Leo A.B. Joosten, Mihai G. Netea, Willem J.M. Mulder, Johan van der Vlag, Abraham J.P. Teunissen, Raphaël Duivenvoorden

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Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils by Luigi Grassi, Farzin Pourfarzad, Sebastian Ullrich, Angelika Merkel, Felipe Were, Enrique Carrillo-de-Santa-Pau, Guoqiang Yi, Ida H. Hiemstra, Anton T.J. Tool, Erik Mul, Juliane Perner, Eva Janssen-Megens, Kim Berentsen, Hinri Kerstens, Ehsan Habibi, Marta Gut, Marie Laure Yaspo, Matthias Linser, Ernesto Lowy, Avik Datta, Laura Clarke, Paul Flicek, Martin Vingron, Dirk Roos, Timo K. van den Berg, Simon Heath, Daniel Rico, Mattia Frontini, Myrto Kostadima, Ivo Gut, Alfonso Valencia, Willem H. Ouwehand, Hendrik G. Stunnenberg, Joost H.A. Martens, Taco W. Kuijpers

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The EHA Research Roadmap: Normal Hematopoiesis by Thierry Jaffredo, Alessandra Balduini, Anna Bigas, Rosa Bernardi, Dominique Bonnet, Bruno Canque, Pierre Charbord, Anna Cumano, Ruud Delwel, Charles Durand, Willem Fibbe, Lesley Forrester, Lucia de Franceschi, Cedric Ghevaert, Bjørn Gjertsen, Berthold Gottgens, Thomas Graf, Olaf Heidenreich, Olivier Hermine, Douglas Higgs, Marina Kleanthous, Hannes Klump, Valerie Kouskoff, Daniela Krause, George Lacaud, Cristina Lo Celso, Joost H.A. Martens, Simón Méndez-Ferrer, Pablo Menendez, Robert Oostendorp, Sjaak Philipsen, Bo Porse, Marc Raaijmakers, Catherine Robin, Henk Stunnenberg, Kim Theilgaard-Mönch, Ivo Touw, William Vainchenker, Joan-Lluis Vives Corrons, Laurent Yvernogeau, Jan Jacob Schuringa

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