Moonshot for Precision Medicine by Jordi Rodon

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Decentralized Clinical Trials in Early Drug Development—A Framework Proposal by Diogo J. Silva, Blessie Elizabeth Nelson, Jordi Rodon

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Review of Immunogenomics and the Role of Tumor Mutational Burden as a Biomarker for Immunotherapy Response by Javier Ros, Iosune Baraibar, Ana Vivancos, Jordi Rodon

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Enhanced antiviral immunity and dampened inflammation in llama lymph nodes upon MERS-CoV sensing: bridging innate and adaptive cellular immune responses in camelid reservoirs by Jordi Rodon, Jordi Rodon, Nigeer Te, Nigeer Te, Joaquim Segalés, Joaquim Segalés, Júlia Vergara-Alert, Júlia Vergara-Alert, Albert Bensaid, Albert Bensaid

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Blocking transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in llamas by vaccination with a recombinant spike protein by Jordi Rodon, Nisreen M. A. Okba, Nigeer Te, Brenda van Dieren, Berend-Jan Bosch, Albert Bensaid, Joaquim Segalés, Bart L. Haagmans, Júlia Vergara-Alert

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Emergence of mTOR mutation as an acquired resistance mechanism to AKT inhibition, and subsequent response to mTORC1/2 inhibition by Niamh Coleman, Vivek Subbiah, Shubham Pant, Keyur Patel, Sinchita Roy-Chowdhuri, Sireesha Yedururi, Amber Johnson, Timothy A. Yap, Jordi Rodon, Kenna Shaw, Funda Meric-Bernstam

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A risk analysis of alpelisib-induced hyperglycemia in patients with advanced solid tumors and breast cancer by Jordi Rodón, David Demanse, Hope S. Rugo, Howard A. Burris, Rafael Simó, Azeez Farooki, Melissa F. Wellons, Fabrice André, Huilin Hu, Dragica Vuina, Cornelia Quadt, Dejan Juric

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Phase I/II study of BMS-986156 with ipilimumab or nivolumab with or without stereotactic ablative radiotherapy in patients with advanced solid malignancies by Wei Li, James Welsh, Vivek Verma, David S Hong, Nathan I Comeaux, Joe Y Chang, Jordi Rodon Ahnert, Daniel D Karp, Ecaterina E Dumbrava, Xinyan Xu, Girish S Shroff, Aileen Chen

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IOLite: phase 1b trial of doublet/triplet combinations of dostarlimab with niraparib, carboplatin–paclitaxel, with or without bevacizumab in patients with advanced cancer by Wei Guo, Manish R Patel, Nashat Gabrail, Jordi Rodon, Erika Hamilton, Timothy A Yap, Meghan Duncan, Alberto Bessudo, Jasgit Sachdev, Lena Evilevitch, Sujatha Kumar, Sharon Lu, Bruce J Dezube

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627 The effect of LNS8801 in combination with pembrolizumab in patients with treatment-refractory cutaneous melanoma by Sapna Patel, Alain Mita, Kyriakos P Papadopoulos, Justine Cohen, Alexander Shoushtari, Jordi Rodon, Marlana Orloff, Marya Chaney, Carolyn Muller, Jessica Lin, Tina Garyantes, Monica Mita, Christopher Natale, Jeffrey Ishizuka

584 Phase I/II study to evaluate the safety and tolerability of avelumab in combination with other anti-cancer therapies in patients with advanced malignancies by Aung Naing, Funda Meric-Bernstam, Shubham Pant, Milind Javle, Juhee Song, Anas Alshawa, Bettzy Stephen, Abdulrazzak Zarifa, Jordi Rodon, Yali Yang, Robert A Wolff, Anne Knisely, Van Morris, Jibran Ahmed

Phase I study of sapanisertib (CB‐228/TAK‐228/MLN0128) in combination with ziv‐aflibercept in patients with advanced solid tumors by Niamh Coleman, Bettzy Stephen, Siqing Fu, Daniel Karp, Vivek Subbiah, Jordi Rodon Ahnert, Sarina A. Piha‐Paul, John Wright, Senait N. Fessahaye, Fengying Ouyang, Bulent Yilmaz, Funda Meric‐Bernstam, Aung Naing

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Extended Viral Shedding of MERS-CoV Clade B Virus in Llamas Compared with African Clade C Strain by Jordi Rodon, Anna Z. Mykytyn, Nigeer Te, Nisreen M.A. Okba, Mart M. Lamers, Lola Pailler-García, Guillermo Cantero, Irina Albulescu, Berend-Jan Bosch, Malik Peiris, Albert Bensaid, Júlia Vergara-Alert, Bart L. Haagmans, Joaquim Segalés

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Biphasic MERS-CoV Incidence in Nomadic Dromedaries with Putative Transmission to Humans, Kenya, 2022–2023 by Brian Maina Ogoti, Victor Riitho, Johanna Wildemann, Nyamai Mutono, Julia Tesch, Jordi Rodon, Kaneemozhe Harichandran, Jackson Emanuel, Elisabeth Möncke-Buchner, Stella Kiambi, Julius Oyugi, Marianne Mureithi, Victor M. Corman, Christian Drosten, Samuel M. Thumbi, Marcel A. Müller

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Agreement and differential use of laboratory methods for the detection and quantification of SARS-CoV-2 in experimentally infected animals by Carla Usai, Carla Usai, Lola Pailler-García, Lola Pailler-García, Cristina Lorca-Oró, Cristina Lorca-Oró, Leira Fernández-Bastit, Leira Fernández-Bastit, Núria Roca, Núria Roca, Marco Brustolin, Marco Brustolin, Jordi Rodon, Jordi Rodon, Mónica Pérez, Mónica Pérez, Guillermo Cantero, Guillermo Cantero, Jorge Carrillo, Jorge Carrillo, Jorge Carrillo, Nuria Izquierdo-Useros, Nuria Izquierdo-Useros, Nuria Izquierdo-Useros, Julià Blanco, Julià Blanco, Julià Blanco, Julià Blanco, Bonaventura Clotet, Bonaventura Clotet, Sebastián Napp, Sebastián Napp, Joaquim Segalés, Joaquim Segalés, Júlia Vergara-Alert, Júlia Vergara-Alert

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Susceptibility of Domestic Goat (<i>Capra aegagrus hircus</i>) to Experimental Infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) B.1.351/Beta Variant by Leira Fernández-Bastit, Núria Roca, Miguel Romero-Durana, Jordi Rodon, Guillermo Cantero, Óscar García, Carlos López, Mònica Pérez, Rosa López, Jorge Carrillo, Nuria Izquierdo-Useros, Julià Blanco, Bonaventura Clotet, Joan Pujols, Júlia Vergara-Alert, Joaquim Segalés, Cristina Lorca-Oró

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First Detection of SARS-CoV-2 Delta (B.1.617.2) Variant of Concern in a Dog with Clinical Signs in Spain by Leira Fernández-Bastit, Jordi Rodon, Edwards Pradenas, Silvia Marfil, Benjamin Trinité, Mariona Parera, Núria Roca, Anna Pou, Guillermo Cantero, Cristina Lorca-Oró, Jorge Carrillo, Nuria Izquierdo-Useros, Bonaventura Clotet, Marc Noguera-Julián, Julià Blanco, Júlia Vergara-Alert, Joaquim Segalés

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Ongoing Evolution of Middle East Respiratory Syndrome Coronavirus, Saudi Arabia, 2023–2024 by Ahmed M. Hassan, Barbara Mühlemann, Tagreed L. Al-Subhi, Jordi Rodon, Sherif A. El-Kafrawy, Ziad Memish, Julia Melchert, Tobias Bleicker, Tiina Mauno, Stanley Perlman, Alimuddin Zumla, Terry C. Jones, Marcel A. Müller, Victor M. Corman, Christian Drosten, Esam I. Azhar

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Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altered breast cancer by Turcin Saridogan, Argun Akcakanat, Ming Zhao, Kurt W. Evans, Erkan Yuca, Stephen Scott, Bryce P. Kirby, Xiaofeng Zheng, Min Jin Ha, Huiqin Chen, Patrick K. S. Ng, Timothy P. DiPeri, Gordon B. Mills, Jordi Rodon Ahnert, Senthil Damodaran, Funda Meric-Bernstam

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Author response to Cunha et al by Vivek Subbiah, Sara Ahmed, Christian Rolfo, Aung Naing, Joud Hajjar, Bettzy Stephen, Jordi Rodon Ahnert, Daniel D Karp, Rivka R Colen, Murat Ak, Mira Ayoub, Nabil Elshafeey, Priyadarshini Mamindla, Pascal O Zinn, Chaan Ng, Raghu Vikram, Spyridon Bakas, Christine B Peterson

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