High-throughput nephelometry methodology for qualitative determination of aqueous solubility of chemical libraries by Jose Brea, Maria J. Varela, Geert A. Daudey, Maria I. Loza

Get full text

Novel Phthalazin-1(2H)-One Derivatives Displaying a Dithiocarbamate Moiety as Potential Anticancer Agents by Noemí Vila, Pedro Besada, José Brea, María Isabel Loza, Carmen Terán

Get full text

5-HT2 receptor binding, functional activity and selectivity in N-benzyltryptamines. by Miguel Toro-Sazo, José Brea, María I Loza, Marta Cimadevila, Bruce K Cassels

Get full text

A Robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery by Gemma Navarro, Eddy Sotelo, Iu Raïch, María Isabel Loza, Jose Brea, Maria Majellaro

Get full text

Cognitive Deficit in Schizophrenia: From Etiology to Novel Treatments by Antón L. Martínez, José Brea, Sara Rico, María Teresa de los Frailes, María Isabel Loza

Get full text

Fingerprint-Based Machine Learning Approach to Identify Potent and Selective 5-HT2BR Ligands by Krzysztof Rataj, Ádám Andor Kelemen, José Brea, María Isabel Loza, Andrzej J. Bojarski, György Miklós Keserű

Get full text

Dibenzofuranylethylamines as 5‑HT2A/2C Receptor Agonists by Thirumal Yempala, José Brea, María Isabel Loza, Douglas J. Matthies, Gerald Zapata-Torres, Bruce K. Cassels

Get full text

Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite shortening. by Antón L Martínez, José Brea, Mateo Barro, Xavier Monroy, Manuel Merlos, Javier Burgueño, María Isabel Loza

Get full text

Congenital and perinatal complications of chikungunya fever: a Latin American experience by Jaime R. Torres, Luiza H. Falleiros-Arlant, Lourdes Dueñas, Jorge Pleitez-Navarrete, Doris M. Salgado, José Brea-Del Castillo

Get full text

Targeting PDE10A GAF Domain with Small Molecules: A Way for Allosteric Modulation with Anti-Inflammatory Effects by Ana M. García, José Brea, Alejandro González-García, Concepción Pérez, María Isabel Cadavid, María Isabel Loza, Ana Martinez, Carmen Gil

Get full text

2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity by Juan Martín-López, Sandra Codony, Clara Bartra, Christophe Morisseau, María Isabel Loza, Coral Sanfeliu, Bruce D. Hammock, José Brea, Santiago Vázquez

Get full text

Epidemiological burden of invasive pneumococcal disease in children and adolescents with predisposing risk factors by Luiza Helena Falleiros-Arlant, Eitan Naaman Berezin, Maria Luisa Avila-Aguero, Maria Catalina Pirez, Angela Gentile, Vesta Richardson, Jose Brea, Cristina Mariño

Get full text

Determinantes del estado de vacunación infantil: abordando la brecha de equidad en República Dominicana-2019 by Manuel Colomé-Hidalgo, Demian Herrera, José Brea Del Castillo, Cecilia María Carrasco Sánchez, Mariana F. Dauhajre Pimentel, Anamarija Jurcev Savicevic, Issael Ramírez

Get full text

Fluorescence based HTS-compatible ligand binding assays for dopamine D3 receptors in baculovirus preparations and live cells by Maris-Johanna Tahk, Tõnis Laasfeld, Tõnis Laasfeld, Elo Meriste, Jose Brea, Maria Isabel Loza, Maria Majellaro, Maria Majellaro, Marialessandra Contino, Eddy Sotelo, Ago Rinken

Get full text

From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-one Core as a New Chemotype of AKT1 Inhibitors for Acute M... by Andrea Astolfi, Francesca Milano, Deborah Palazzotti, Jose Brea, Maria Chiara Pismataro, Mariangela Morlando, Oriana Tabarrini, Maria Isabel Loza, Serena Massari, Maria Paola Martelli, Maria Letizia Barreca

Get full text

Identification of Sodium Transients Through NaV1.5 Channels as Regulators of Differentiation in Immortalized Dorsal Root Ganglia Neurons by Antón L. Martínez, José Brea, Eduardo Domínguez, María J. Varela, Catarina Allegue, Raquel Cruz, Xavier Monroy, Manuel Merlos, Javier Burgueño, Ángel Carracedo, Ángel Carracedo, María Isabel Loza

Get full text

Pharmacological insights emerging from the characterization of a large collection of synthetic cannabinoid receptor agonists designer drugs by Claudia Gioé-Gallo, Sandra Ortigueira, José Brea, Iu Raïch, Jhonny Azuaje, M. Rita Paleo, Maria Majellaro, María Isabel Loza, Cristian O. Salas, Xerardo García-Mera, Gemma Navarro, Eddy Sotelo

Get full text

Insights into the Pharmacokinetics and In Vitro Cell-Based Studies of the Imidazoline I₂ Receptor Ligand B06 by Andrea Bagán, José A. Morales-García, Christian Griñán-Ferré, Caridad Díaz, José Pérez del Palacio, Maria C. Ramos, Francisca Vicente, Belén Pérez, José Brea, María Isabel Loza, Mercè Pallàs, Carmen Escolano

Get full text

Risks of low vaccination coverage and strategies to prevent the resurgence of vaccine-preventable diseases in infants in the COVID-19 pandemic scenario: recommendations for Latin A... by Maria L. Avila Agüero, Jose Brea Del Castillo, Luiza Helena Falleiros-Arlant, Eitan Berezín, Jose Cassio de Moraes, Carlos Torres-Martínez, Eduardo L. Lopez, María E. Castillo, Almudena Laris-Gonzalez, Fortino Solorzano, Angela Gentile, Juan Pablo Torres Torretti, Eduardo López-Medina

Get full text

The application of the open pharmacological concepts triple store (open PHACTS) to support drug discovery research. by Joseline Ratnam, Barbara Zdrazil, Daniela Digles, Emiliano Cuadrado-Rodriguez, Jean-Marc Neefs, Hannah Tipney, Ronald Siebes, Andra Waagmeester, Glyn Bradley, Chau Han Chau, Lars Richter, Jose Brea, Chris T Evelo, Edgar Jacoby, Stefan Senger, Maria Isabel Loza, Gerhard F Ecker, Christine Chichester

Get full text