Extracellular calcium promotes bone formation from bone marrow mesenchymal stem cells by amplifying the effects of BMP-2 on SMAD signalling. by Rubén Aquino-Martínez, Natalia Artigas, Beatriz Gámez, José Luis Rosa, Francesc Ventura

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HERCing: Structural and Functional Relevance of the Large HERC Ubiquitin Ligases by Jesús García-Cano, Arturo Martinez-Martinez, Joan Sala-Gaston, Leonardo Pedrazza, Jose Luis Rosa

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Functional EF-hands in neuronal calcium sensor GCAP2 determine its phosphorylation state and subcellular distribution in vivo, and are essential for photoreceptor cell integrity. by Natalia López-Del Hoyo, Santiago López-Begines, Jose Luis Rosa, Jeannie Chen, Ana Méndez

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Large HERCs Function as Tumor Suppressors by Taiane Schneider, Arturo Martinez-Martinez, Monica Cubillos-Rojas, Ramon Bartrons, Francesc Ventura, Jose Luis Rosa

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Interplay between BMPs and Reactive Oxygen Species in Cell Signaling and Pathology by Cristina Sánchez-de-Diego, José Antonio Valer, Carolina Pimenta-Lopes, José Luis Rosa, Francesc Ventura

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ACVR1 Function in Health and Disease by José Antonio Valer, Cristina Sánchez-de-Diego, Carolina Pimenta-Lopes, Jose Luis Rosa, Francesc Ventura

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Inhibition of phosphatidylinositol 3‐kinase α (PI3Kα) prevents heterotopic ossification by José Antonio Valer, Cristina Sánchez‐de‐Diego, Beatriz Gámez, Yuji Mishina, José Luis Rosa, Francesc Ventura

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Regulation of the MDM2‐p53 pathway by the ubiquitin ligase HERC2 by Jesús García‐Cano, Susana Sánchez‐Tena, Joan Sala‐Gaston, Agnès Figueras, Francesc Viñals, Ramon Bartrons, Francesc Ventura, Jose Luis Rosa

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Mesenchymal stem cells decrease lung inflammation during sepsis, acting through inhibition of the MAPK pathway by Leonardo Pedrazza, Monica Cubillos-Rojas, Fernanda Cristina de Mesquita, Carolina Luft, Aline Andrea Cunha, Jose Luis Rosa, Jarbas Rodrigues de Oliveira

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Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mutation in HERC1 E3 ubiquitin ligase. by Tomoji Mashimo, Ouadah Hadjebi, Fabiola Amair-Pinedo, Toshiko Tsurumi, Francina Langa, Tadao Serikawa, Constantino Sotelo, Jean-Louis Guénet, Jose Luis Rosa

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The p38α MAPK function in osteoprecursors is required for bone formation and bone homeostasis in adult mice. by Edgardo Rodríguez-Carballo, Beatriz Gámez, Lara Sedó-Cabezón, Manuela Sánchez-Feutrie, Antonio Zorzano, Cristina Manzanares-Céspedes, José Luis Rosa, Francesc Ventura

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Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder by Joan Sala-Gaston, Eva M. Pérez-Villegas, José A. Armengol, Lettie E. Rawlins, Emma L. Baple, Andrew H. Crosby, Francesc Ventura, Jose Luis Rosa

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Correction: Contribution of S6K1/MAPK Signaling Pathways in the Response to Oxidative Stress: Activation of RSK and MSK by Hydrogen Peroxide. by Anna Siebel, Monica Cubillos-Rojas, Roberto Christ Santos, Taiane Schneider, Carla Denise Bonan, Ramon Bartrons, Francesc Ventura, Jarbas Rodrigues de Oliveira, Jose Luis Rosa

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NRF2 function in osteocytes is required for bone homeostasis and drives osteocytic gene expression by Cristina Sánchez-de-Diego, Leonardo Pedrazza, Carolina Pimenta-Lopes, Arturo Martinez-Martinez, Norma Dahdah, José Antonio Valer, Pablo Garcia-Roves, Jose Luis Rosa, Francesc Ventura

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HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling by Leonardo Pedrazza, Arturo Martinez-Martinez, Cristina Sánchez-de-Diego, José Antonio Valer, Carolina Pimenta-Lopes, Joan Sala-Gaston, Michal Szpak, Chris Tyler-Smith, Francesc Ventura, Jose Luis Rosa

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Glucose Restriction Promotes Osteocyte Specification by Activating a PGC-1α-Dependent Transcriptional Program by Cristina Sánchez-de-Diego, Natalia Artigas, Carolina Pimenta-Lopes, José Antonio Valer, Benjamin Torrejon, Pau Gama-Pérez, Josep A. Villena, Pablo M. Garcia-Roves, José Luis Rosa, Francesc Ventura

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HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory by Eva M. Pérez-Villegas, Mikel Pérez-Rodríguez, José V. Negrete-Díaz, José V. Negrete-Díaz, Rocío Ruiz, Rocío Ruiz, Jose Luis Rosa, Guillermo Alvarez de Toledo, Antonio Rodríguez-Moreno, José A. Armengol

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Liraglutide improves liver microvascular dysfunction in cirrhosis: Evidence from translational studies by Fernanda Cristina de Mesquita, Sergi Guixé-Muntet, Anabel Fernández-Iglesias, Raquel Maeso-Díaz, Sergi Vila, Diana Hide, Martí Ortega-Ribera, José Luís Rosa, Juan Carlos García-Pagán, Jaime Bosch, Jarbas Rodrigues de Oliveira, Jordi Gracia-Sancho

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Post-translational regulation of retinal IMPDH1 in vivo to adjust GTP synthesis to illumination conditions by Anna Plana-Bonamaisó, Santiago López-Begines, David Fernández-Justel, Alexandra Junza, Ariadna Soler-Tapia, Jordi Andilla, Pablo Loza-Alvarez, Jose Luis Rosa, Esther Miralles, Isidre Casals, Oscar Yanes, Pedro de la Villa, Ruben M Buey, Ana Méndez

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