Effect of Interleukin-15 Receptor Alpha Ablation on the Metabolic Responses to Moderate Exercise Simulated by in vivo Isometric Muscle Contractions by Emanuele Loro, Cholsoon Jang, William J. Quinn, Joseph A. Baur, Zoltan P. Arany, Tejvir S. Khurana

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Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2 by Lan eYe, Behzad eVaramini, Dudley W. Lamming, David M. Sabatini, Joseph A. Baur

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Supplemental arginine vasopressin during the resuscitation of severe hemorrhagic shock preserves renal mitochondrial function. by Carrie A Sims, Guan Yuxia, Khushboo Singh, Evan C Werlin, Patrick M Reilly, Joseph A Baur

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An Alternate Splicing Variant of the Human Telomerase Catalytic Subunit Inhibits Telomerase Activity by Xiaoming Yi, Dennis M. White, Dara L. Aisner, Joseph A. Baur, Woodring E. Wright, Jerry W. Shay

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Visualizing subcellular changes in the NAD(H) pool size versus redox state using fluorescence lifetime imaging microscopy of NADH by Angela Song, Nicole Zhao, Diana C. Hilpert, Caroline Perry, Joseph A. Baur, Douglas C. Wallace, Patrick M. Schaefer

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4582 NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) DEPLETION MUST BE SEVERE TO INDUCE CARDIAC DYSFUNCTION AND EVENTUAL FAILURE by Timothy Luongo, Lin Wang, Karthikeyani Chellappa, Melanie R. McReynolds, Daniel P. Kelly, Joshua D. Rabinowitz, Joseph A. Baur

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Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice by Patrick M. Schaefer, Jessica Huang, Arrienne Butic, Caroline Perry, Tal Yardeni, Wendy Tan, Ryan Morrow, Joseph A. Baur, Douglas C. Wallace

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SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside by Sarmistha Mukherjee, James Mo, Lauren M. Paolella, Caroline E. Perry, Jade Toth, Mindy M. Hugo, Qingwei Chu, Qian Tong, Karthikeyani Chellappa, Joseph A. Baur

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mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia by Lauren M. Paolella, Sarmistha Mukherjee, Cassie M. Tran, Bruna Bellaver, Mindy Hugo, Timothy S. Luongo, Swapnil V. Shewale, Wenyun Lu, Karthikeyani Chellappa, Joseph A. Baur

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Nicotinamide adenine dinucleotide is transported into mammalian mitochondria by Antonio Davila, Ling Liu, Karthikeyani Chellappa, Philip Redpath, Eiko Nakamaru-Ogiso, Lauren M Paolella, Zhigang Zhang, Marie E Migaud, Joshua D Rabinowitz, Joseph A Baur

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Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 receptor agonism by Elizabeth Nunn, Natasha Jaiswal, Matthew Gavin, Kahealani Uehara, Megan Stefkovich, Karima Drareni, Ryan Calhoun, Michelle Lee, Corey D. Holman, Joseph A. Baur, Patrick Seale, Paul M. Titchenell

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Accumulation of 3-hydroxytetradecenoic acid: Cause or corollary of glucolipotoxic impairment of pancreatic β-cell bioenergetics? by Nicolai M. Doliba, Qing Liu, Changhong Li, Jie Chen, Pan Chen, Chengyang Liu, David W. Frederick, Joseph A. Baur, Michael J. Bennett, Ali Naji, Franz M. Matschinsky

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Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mic... by Stefano Tarantini, Marta Noa Valcarcel-Ares, Peter Toth, Andriy Yabluchanskiy, Zsuzsanna Tucsek, Tamas Kiss, Peter Hertelendy, Michael Kinter, Praveen Ballabh, Zoltán Süle, Eszter Farkas, Joseph A. Baur, David A. Sinclair, Anna Csiszar, Zoltan Ungvari

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Primary respiratory chain disease causes tissue-specific dysregulation of the global transcriptome and nutrient-sensing signaling network. by Zhe Zhang, Mai Tsukikawa, Min Peng, Erzsebet Polyak, Eiko Nakamaru-Ogiso, Julian Ostrovsky, Shana McCormack, Emily Place, Colleen Clarke, Gail Reiner, Elizabeth McCormick, Eric Rappaport, Richard Haas, Joseph A Baur, Marni J Falk

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Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser by Keerthana Gnanapradeepan, Julia I-Ju Leu, Subhasree Basu, Thibaut Barnoud, Madeline Good, Joyce V Lee, William J Quinn, Che-Pei Kung, Rexford Ahima, Joseph A Baur, Kathryn E Wellen, Qin Liu, Zachary T Schug, Donna L George, Maureen E Murphy

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What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. by Ole Vang, Nihal Ahmad, Clifton A Baile, Joseph A Baur, Karen Brown, Anna Csiszar, Dipak K Das, Dominique Delmas, Carmem Gottfried, Hung-Yun Lin, Qing-Yong Ma, Partha Mukhopadhyay, Namasivayam Nalini, John M Pezzuto, Tristan Richard, Yogeshwer Shukla, Young-Joon Surh, Thomas Szekeres, Tomasz Szkudelski, Thomas Walle, Joseph M Wu

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Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes. by Prasanna M Chandramouleeswaran, Manti Guha, Masataka Shimonosono, Kelly A Whelan, Hisatsugu Maekawa, Uma M Sachdeva, Gordon Ruthel, Sarmistha Mukherjee, Noah Engel, Michael V Gonzalez, James Garifallou, Shinya Ohashi, Andres J Klein-Szanto, Clementina A Mesaros, Ian A Blair, Renata Pellegrino da Silva, Hakon Hakonarson, Eishi Noguchi, Joseph A Baur, Hiroshi Nakagawa

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Lactate Limits T Cell Proliferation via the NAD(H) Redox State by William J. Quinn, III, Jing Jiao, Tara TeSlaa, Jason Stadanlick, Zhonglin Wang, Liqing Wang, Tatiana Akimova, Alessia Angelin, Patrick M. Schäfer, Michelle D. Cully, Caroline Perry, Piotr K. Kopinski, Lili Guo, Ian A. Blair, Louis R. Ghanem, Michael S. Leibowitz, Wayne W. Hancock, Edmund K. Moon, Matthew H. Levine, Evgeniy B. Eruslanov, Douglas C. Wallace, Joseph A. Baur, Ulf H. Beier

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Limiting Mrs2-dependent mitochondrial Mg2+ uptake induces metabolic programming in prolonged dietary stress by Travis R. Madaris, Manigandan Venkatesan, Soumya Maity, Miriam C. Stein, Neelanjan Vishnu, Mridula K. Venkateswaran, James G. Davis, Karthik Ramachandran, Sukanthathulse Uthayabalan, Cristel Allen, Ayodeji Osidele, Kristen Stanley, Nicholas P. Bigham, Terry M. Bakewell, Melanie Narkunan, Amy Le, Varsha Karanam, Kang Li, Aum Mhapankar, Luke Norton, Jean Ross, M. Imran Aslam, W. Brian Reeves, Brij B. Singh, Jeffrey Caplan, Justin J. Wilson, Peter B. Stathopulos, Joseph A. Baur, Muniswamy Madesh

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Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation by Dhanendra Tomar, Fabián Jaña, Zhiwei Dong, William J. Quinn, III, Pooja Jadiya, Sarah L. Breves, Cassidy C. Daw, Subramanya Srikantan, Santhanam Shanmughapriya, Neeharika Nemani, Edmund Carvalho, Aparna Tripathi, Alison M. Worth, Xueqian Zhang, Roshanak Razmpour, Ajay Seelam, Stephen Rhode, Anuj V. Mehta, Michael Murray, Daniel Slade, Servio H. Ramirez, Prashant Mishra, Glenn S. Gerhard, Jeffrey Caplan, Luke Norton, Kumar Sharma, Sudarsan Rajan, Darius Balciunas, Dayanjan S. Wijesinghe, Rexford S. Ahima, Joseph A. Baur, Muniswamy Madesh

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