Gene therapy for the treatment of chronic peripheral nervous system pain por William F. Goins, Justus B. Cohen, Joseph C. Glorioso

Ligazón do recurso

Oncolytic herpes simplex viruses designed for targeted treatment of EGFR-bearing tumors por Selene Ingusci, Bonnie L. Hall, Justus B. Cohen, Joseph C. Glorioso

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Herpes Simplex Virus Vectors for Gene Transfer to the Central Nervous System por Sara Artusi, Yoshitaka Miyagawa, William F. Goins, Justus B. Cohen, Joseph C. Glorioso

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Engineered HSV vector achieves safe long-term transgene expression in the central nervous system por Gianluca Verlengia, Yoshitaka Miyagawa, Selene Ingusci, Justus B. Cohen, Michele Simonato, Joseph C. Glorioso

Ligazón do recurso

Novel mutations in UL24 and gH rescue efficient infection of an HSV vector retargeted to TrkA por Marco Marzulli, Bonnie L. Hall, Mingdi Zhang, William F. Goins, Justus B. Cohen, Joseph C. Glorioso

Ligazón do recurso

Deletion of the Virion Host Shut-off Gene Enhances Neuronal-Selective Transgene Expression from an HSV Vector Lacking Functional IE Genes por Yoshitaka Miyagawa, Gianluca Verlengia, Bonnie Reinhart, Fang Han, Hiroaki Uchida, Silvia Zucchini, William F. Goins, Michele Simonato, Justus B. Cohen, Joseph C. Glorioso

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Point Mutations in Retargeted gD Eliminate the Sensitivity of EGFR/EGFRvIII-Targeted HSV to Key Neutralizing Antibodies por Ceren Tuzmen, Tina M. Cairns, Doina Atanasiu, Huan Lou, Wan Ting Saw, Bonnie L. Hall, Justus B. Cohen, Gary H. Cohen, Joseph C. Glorioso

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Inhibition of Indoleamine-2,3-dioxygenase (IDO) in Glioblastoma Cells by Oncolytic Herpes Simplex Virus por Bonnie Reinhart, Lucia Mazzacurati, Adriana Forero, Chang-Sook Hong, Junichi Eguchi, Hideho Okada, Wendy Fellows, Ajay Niranjan, Justus B. Cohen, Joseph C. Glorioso, Paola Grandi

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Evaluation of parameters for efficient purification and long-term storage of herpes simplex virus-based vectors por Seiji Kuroda, Yoshitaka Miyagawa, Makoto Sukegawa, Taro Tomono, Motoko Yamamoto, Kumi Adachi, Gianluca Verlengia, William F. Goins, Justus B. Cohen, Joseph C. Glorioso, Takashi Okada

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Treatment of glioblastoma with current oHSV variants reveals differences in efficacy and immune cell recruitment por Joseph W. Jackson, Bonnie L. Hall, Marco Marzulli, Vrusha K. Shah, Lisa Bailey, E. Antonio Chiocca, William F. Goins, Gary Kohanbash, Justus B. Cohen, Joseph C. Glorioso

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Protocol Optimization for the Production of the Non-Cytotoxic JΔNI5 HSV Vector Deficient in Expression of Immediately Early Genes por Seiji Kuroda, Yoshitaka Miyagawa, Yuriko Sato, Motoko Yamamoto, Kumi Adachi, Hiromi Kinoh, William F. Goins, Justus B. Cohen, Joseph C. Glorioso, Nobuhiko Taniai, Hiroshi Yoshida, Takashi Okada

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GBM-Targeted oHSV Armed with Matrix Metalloproteinase 9 Enhances Anti-tumor Activity and Animal Survival por Paola Sette, Nduka Amankulor, Aofei Li, Marco Marzulli, Daniela Leronni, Mingdi Zhang, William F. Goins, Balveen Kaur, Chelsea Bolyard, Timothy P. Cripe, Jianhua Yu, E. Antonio Chiocca, Joseph C. Glorioso, Paola Grandi

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Disease-modifying rdHSV-CA8* non-opioid analgesic gene therapy treats chronic osteoarthritis pain by activating Kv7 voltage-gated potassium channels por Gerald Z. Zhuang, William F. Goins, Munal B. Kandel, Marco Marzulli, Mingdi Zhang, Joseph C. Glorioso, Yuan Kang, Alexandra E. Levitt, Konstantinos D. Sarantopoulos, Konstantinos D. Sarantopoulos, Roy C. Levitt, Roy C. Levitt, Roy C. Levitt, Roy C. Levitt

Ligazón do recurso

rdHSV-CA8 non-opioid analgesic gene therapy decreases somatosensory neuronal excitability by activating Kv7 voltage-gated potassium channels por Munal B. Kandel, Gerald Z. Zhuang, William F. Goins, Marco Marzulli, Mingdi Zhang, Joseph C. Glorioso, Yuan Kang, Alexandra E. Levitt, Wai-Meng Kwok, Roy C. Levitt, Roy C. Levitt, Roy C. Levitt, Roy C. Levitt, Konstantinos D. Sarantopoulos, Konstantinos D. Sarantopoulos

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Design of an Interferon-Resistant Oncolytic HSV-1 Incorporating Redundant Safety Modalities for Improved Tolerability por Edward M. Kennedy, Terry Farkaly, Peter Grzesik, Jennifer Lee, Agnieszka Denslow, Jacqueline Hewett, Jeffrey Bryant, Prajna Behara, Caitlin Goshert, Daniel Wambua, Ana De Almeida, Judith Jacques, Damian Deavall, James B. Rottman, Joseph C. Glorioso, Mitchell H. Finer, Brian B. Haines, Christophe Quéva, Lorena Lerner

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Oncolytic HSV virotherapy in murine sarcomas differentially triggers an antitumor T-cell response in the absence of virus permissivity por Jennifer L Leddon, Chun-Yu Chen, Mark A Currier, Pin-Yi Wang, Francesca A Jung, Nicholas L Denton, Kevin M Cripe, Kellie B Haworth, Michael A Arnold, Amy C Gross, Timothy D Eubank, William F Goins, Joseph C Glorioso, Justus B Cohen, Paola Grandi, David A Hildeman, Timothy P Cripe

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