Showing 1 - 14 results of 14 for search 'Joseph W. Lynch', query time: 0.04s Refine Results
  1. 1
    γ1-Containing GABA-A Receptors Cluster at Synapses Where they Mediate Slower Synaptic Currents than γ2-Containing GABA-A Receptors

    γ1-Containing GABA-A Receptors Cluster at Synapses Where they Mediate Slower Synaptic Currents than γ2-Containing GABA-A Receptors by Christine L. Dixon, Pankaj Sah, Angelo Keramidas, Joseph W. Lynch, Joseph W. Lynch, Nela Durisic

    Published 2017-06-01
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  2. 2
    Structure-Function Analysis of the GlyR α2 Subunit Autism Mutation p.R323L Reveals a Gain-of-Function

    Structure-Function Analysis of the GlyR α2 Subunit Autism Mutation p.R323L Reveals a Gain-of-Function by Yan Zhang, Thi Nhu Thao Ho, Robert J. Harvey, Joseph W. Lynch, Joseph W. Lynch, Angelo Keramidas

    Published 2017-05-01
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  3. 3
    β Subunit M2-M3 loop conformational changes are uncoupled from α1 β glycine receptor channel gating: implications for human hereditary hyperekplexia.

    β Subunit M2-M3 loop conformational changes are uncoupled from α1 β glycine receptor channel gating: implications for human hereditary hyperekplexia. by Qiang Shan, Lu Han, Joseph W Lynch

    Published 2011-01-01
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  4. 4
    Fluorescence-based high-throughput functional profiling of ligand-gated ion channels at the level of single cells.

    Fluorescence-based high-throughput functional profiling of ligand-gated ion channels at the level of single cells. by Sahil Talwar, Joseph W Lynch, Daniel F Gilbert

    Published 2013-01-01
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  5. 5
    Inhibitory synapse deficits caused by familial α1 GABAA receptor mutations in epilepsy

    Inhibitory synapse deficits caused by familial α1 GABAA receptor mutations in epilepsy by Xiumin Chen, Nela Durisic, Joseph W. Lynch, Angelo Keramidas

    Published 2017-12-01
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  6. 6
    Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors

    Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors by Xiumin Chen, Angelo Keramidas, Robert J. Harvey, Joseph W. Lynch

    Published 2020-07-01
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  7. 7
    SAHA (Vorinostat) Corrects Inhibitory Synaptic Deficits Caused by Missense Epilepsy Mutations to the GABAA Receptor γ2 Subunit

    SAHA (Vorinostat) Corrects Inhibitory Synaptic Deficits Caused by Missense Epilepsy Mutations to the GABAA Receptor γ2 Subunit by Nela Durisic, Angelo Keramidas, Christine L. Dixon, Joseph W. Lynch

    Published 2018-03-01
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  8. 8
    Structure/Function Studies of the α4 Subunit Reveal Evolutionary Loss of a GlyR Subtype Involved in Startle and Escape Responses

    Structure/Function Studies of the α4 Subunit Reveal Evolutionary Loss of a GlyR Subtype Involved in Startle and Escape Responses by Sophie Leacock, Parnayan Syed, Victoria M. James, Anna Bode, Koichi Kawakami, Angelo Keramidas, Maximiliano Suster, Joseph W. Lynch, Joseph W. Lynch, Robert J. Harvey, Robert J. Harvey

    Published 2018-01-01
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  9. 9
    Effects of glutamate and ivermectin on single glutamate-gated chloride channels of the parasitic nematode H. contortus.

    Effects of glutamate and ivermectin on single glutamate-gated chloride channels of the parasitic nematode H. contortus. by Mohammed Atif, Argel Estrada-Mondragon, Bindi Nguyen, Joseph W Lynch, Angelo Keramidas

    Published 2017-10-01
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  10. 10
    A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy models

    A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy models by Melissa J. Benson, Nicola K. Thomas, Sahil Talwar, Mark P. Hodson, Joseph W. Lynch, Trent M. Woodruff, Karin Borges

    Published 2015-04-01
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  11. 11
    GluClR-mediated inhibitory postsynaptic currents reveal targets for ivermectin and potential mechanisms of ivermectin resistance.

    GluClR-mediated inhibitory postsynaptic currents reveal targets for ivermectin and potential mechanisms of ivermectin resistance. by Mohammed Atif, Jennifer J Smith, Argel Estrada-Mondragon, Xue Xiao, Angela A Salim, Robert J Capon, Joseph W Lynch, Angelo Keramidas

    Published 2019-01-01
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  12. 12
    Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABAA receptors

    Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABAA receptors by Meng Wang, Edmund Cotter, Ya-Juan Wang, Xu Fu, Angela L. Whittsette, Joseph W. Lynch, R. Luke Wiseman, Jeffery W. Kelly, Angelo Keramidas, Ting-Wei Mu

    Published 2022-04-01
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  13. 13
    Novel missense mutations in the glycine receptor β subunit gene (GLRB) in startle disease

    Novel missense mutations in the glycine receptor β subunit gene (GLRB) in startle disease by Victoria M. James, Anna Bode, Seo-Kyung Chung, Jennifer L. Gill, Maartje Nielsen, Frances M. Cowan, Mihailo Vujic, Rhys H. Thomas, Mark I. Rees, Kirsten Harvey, Angelo Keramidas, Maya Topf, Ieke Ginjaar, Joseph W. Lynch, Robert J. Harvey

    Published 2013-04-01
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  14. 14
    Loss, Gain and Altered Function of GlyR α2 Subunit Mutations in Neurodevelopmental Disorders

    Loss, Gain and Altered Function of GlyR α2 Subunit Mutations in Neurodevelopmental Disorders by Xiumin Chen, Katie A. Wilson, Natascha Schaefer, Lachlan De Hayr, Lachlan De Hayr, Mark Windsor, Mark Windsor, Emmanuel Scalais, Germaine van Rijckevorsel, Katrien Stouffs, Carmen Villmann, Megan L. O’Mara, Megan L. O’Mara, Joseph W. Lynch, Robert J. Harvey, Robert J. Harvey

    Published 2022-04-01
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