Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits by Michael F. Wangler, Yanhui Hu, Joshua M. Shulman

Get full text

Progress toward an integrated understanding of Parkinson's disease [version 1; referees: 2 approved] by Maxime W.C. Rousseaux, Joshua M. Shulman, Joseph Jankovic

Get full text

Quantifying cognitive resilience in Alzheimer's Disease: The Alzheimer's Disease Cognitive Resilience Score. by Tianyi Yao, Elizabeth Sweeney, John Nagorski, Joshua M Shulman, Genevera I Allen

Get full text

Intermediate phenotypes identify divergent pathways to Alzheimer's disease. by Joshua M Shulman, Lori B Chibnik, Cristin Aubin, Julie A Schneider, David A Bennett, Philip L De Jager

Get full text

Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer’s Disease by Qi Guo, Eric B. Dammer, Eric B. Dammer, Maotian Zhou, Sean R. Kundinger, Marla Gearing, Marla Gearing, James J. Lah, James J. Lah, Allan I. Levey, Allan I. Levey, Joshua M. Shulman, Joshua M. Shulman, Nicholas T. Seyfried, Nicholas T. Seyfried, Nicholas T. Seyfried

Get full text

Tau polarizes an aging transcriptional signature to excitatory neurons and glia by Timothy Wu, Jennifer M Deger, Hui Ye, Caiwei Guo, Justin Dhindsa, Brandon T Pekarek, Rami Al-Ouran, Zhandong Liu, Ismael Al-Ramahi, Juan Botas, Joshua M Shulman

Get full text

Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain by Hui Ye, Shamsideen A Ojelade, David Li-Kroeger, Zhongyuan Zuo, Liping Wang, Yarong Li, Jessica YJ Gu, Ulrich Tepass, Avital Adah Rodal, Hugo J Bellen, Joshua M Shulman

Get full text

Integrated analysis of the aging brain transcriptome and proteome in tauopathy by Carl Grant Mangleburg, Timothy Wu, Hari K. Yalamanchili, Caiwei Guo, Yi-Chen Hsieh, Duc M. Duong, Eric B. Dammer, Philip L. De Jager, Nicholas T. Seyfried, Zhandong Liu, Joshua M. Shulman

Get full text

A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis. by Zongqi Xia, Lori B Chibnik, Bonnie I Glanz, Maria Liguori, Joshua M Shulman, Dong Tran, Samia J Khoury, Tanuja Chitnis, Todd Holyoak, Howard L Weiner, Charles R G Guttmann, Philip L De Jager

Get full text

cindr, the Drosophila Homolog of the CD2AP Alzheimer’s Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis by Shamsideen A. Ojelade, Tom V. Lee, Nikolaos Giagtzoglou, Lei Yu, Berrak Ugur, Yarong Li, Lita Duraine, Zhongyuan Zuo, Vlad Petyuk, Philip L. De Jager, David A. Bennett, Benjamin R. Arenkiel, Hugo J. Bellen, Joshua M. Shulman

Get full text

Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity. by Meigen Yu, Hui Ye, Ruth B De-Paula, Carl Grant Mangleburg, Timothy Wu, Tom V Lee, Yarong Li, Duc Duong, Bridget Phillips, Carlos Cruchaga, Genevera I Allen, Nicholas T Seyfried, Ismael Al-Ramahi, Juan Botas, Joshua M Shulman

Get full text

Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer’s Disease by Yi-Chen Hsieh, Caiwei Guo, Hari K. Yalamanchili, Measho Abreha, Rami Al-Ouran, Yarong Li, Eric B. Dammer, James J. Lah, Allan I. Levey, David A. Bennett, Philip L. De Jager, Nicholas T. Seyfried, Zhandong Liu, Joshua M. Shulman

Get full text

NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies. by Yousuf O Ali, Hunter M Allen, Lei Yu, David Li-Kroeger, Dena Bakhshizadehmahmoudi, Asante Hatcher, Cristin McCabe, Jishu Xu, Nicole Bjorklund, Giulio Taglialatela, David A Bennett, Philip L De Jager, Joshua M Shulman, Hugo J Bellen, Hui-Chen Lu

Get full text

Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models by Ying-Wooi Wan, Rami Al-Ouran, Carl G. Mangleburg, Thanneer M. Perumal, Tom V. Lee, Katherine Allison, Vivek Swarup, Cory C. Funk, Chris Gaiteri, Mariet Allen, Minghui Wang, Sarah M. Neuner, Catherine C. Kaczorowski, Vivek M. Philip, Gareth R. Howell, Heidi Martini-Stoica, Hui Zheng, Hongkang Mei, Xiaoyan Zhong, Jungwoo Wren Kim, Valina L. Dawson, Ted M. Dawson, Ping-Chieh Pao, Li-Huei Tsai, Jean-Vianney Haure-Mirande, Michelle E. Ehrlich, Paramita Chakrabarty, Yona Levites, Xue Wang, Eric B. Dammer, Gyan Srivastava, Sumit Mukherjee, Solveig K. Sieberts, Larsson Omberg, Kristen D. Dang, James A. Eddy, Phil Snyder, Yooree Chae, Sandeep Amberkar, Wenbin Wei, Winston Hide, Christoph Preuss, Ayla Ergun, Phillip J. Ebert, David C. Airey, Sara Mostafavi, Lei Yu, Hans-Ulrich Klein, Gregory W. Carter, David A. Collier, Todd E. Golde, Allan I. Levey, David A. Bennett, Karol Estrada, T. Matthew Townsend, Bin Zhang, Eric Schadt, Philip L. De Jager, Nathan D. Price, Nilüfer Ertekin-Taner, Zhandong Liu, Joshua M. Shulman, Lara M. Mangravite, Benjamin A. Logsdon

Get full text