Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation by Ryzhakov, G, Almuttaqi, H, Corbin, A, Berthold, DL, Khoyratty, T, Eames, H, Bullers, S, Pearson, C, Ai, Z, Zec, K, Bonham, S, Fischer, R, Jostins-Dean, L, Travis, S, Kessler, B, Udalova, I

Response to anti-IL17 therapy in inflammatory disease is not strongly impacted by genetic background by Zhang, K, Shestopaloff, K, Hollis, B, Kwok, C, Hon, C, Hartmann, N, Tian, C, Wozniak, M, Santos, L, West, D, Gardiner, S, Mallon, A-M, Readie, A, Martin, R, Nichols, T, Beste, M, Zierer, J, Ferrero, E, Vandemeulebroecke, M, Jostins-Dean, L

Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2 by Mukhopadhyay, S, Heinz, E, Porreca, I, Alasoo, K, Yeung, A, Yang, H, Schwerd, T, Forbester, J, Hale, C, Agu, C, Choi, Y, Rodrigues, J, Capitani, M, Jostins-Dean, L, Thomas, D, Travis, S, Gaffney, D, Skarnes, W, Thomson, N, Uhlig, H, Dougan, G, Powrie, F

Defining predictors of responsiveness to advanced therapies in Crohn’s disease and ulcerative colitis: protocol for the IBD-RESPONSE and nested CD-metaRESPONSE prospective, multice... by Wyatt, NJ, Watson, H, Anderson, CA, Kennedy, NA, Raine, T, Ahmad, T, Allerton, D, Bardgett, M, Clark, E, Clewes, D, Cotobal Martin, C, Doona, M, Doyle, JA, Frith, K, Hancock, HC, Hart, AL, Hildreth, V, Irving, PM, Iqbal, S, Kennedy, C, King, A, Lawrence, S, Lees, CW, Lees, R, Satsangi, J, Jostins-Dean, L

Development of methodology to support molecular endotype discovery from synovial fluid of individuals with knee osteoarthritis: The STEpUP OA consortium by Deng, Y, Perry, TA, Hulley, P, Maciewicz, RA, Mitchelmore, J, Perry, D, Larsson, S, Brachat, S, Struglics, A, Appleton, CT, Kluzek, S, Arden, NK, Felson, D, Marsden, B, Tom, BDM, Bondi, L, Kapoor, M, Batchelor, V, Mackay-Alderson, J, Kumar, V, Lohmander, LS, Welting, TJ, Walsh, DA, Valdes, AM, Vincent, TL, Watt, FE, Jostins-Dean, L

A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease by Thomas, T, Friedrich, M, Rich-Griffin, C, Pohin, M, Agarwal, D, Pakpoor, J, Lee, C, Tandon, R, Rendek, A, Aschenbrenner, D, Jainarayanan, A, Voda, A, Siu, JHY, Sanches-Peres, R, Nee, E, Sathananthan, D, Kotliar, D, Todd, P, Kiourlappou, M, Gartner, L, Ilott, N, Issa, F, Hester, J, Turner, J, Mackerodt, J, Marsden, B, Taylor, S, Coles, M, Jostins-Dean, L, Powrie, FM, Travis, S, Uhlig, HH, Dendrou, CA, Buckley, CD

IBD BioResource: an open-access platform of 25 000 patients to accelerate research in Crohn's and Colitis by Parkes, M, IBD BioResource Investigators

Other Authors: “…Jostins-Dean, L…”

Leveraging genome wide association studies and single cell RNA sequencing in inflammatory bowel disease by Voda, A-I

Other Authors: “…Jostins-Dean, L…”