Novel methods in computational analysis and design of protein-protein interactions : applications to phosphoregulated interactions by Joughin, Brian Alan

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Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition by Jenney, Anne P., Sorger, Peter K., Jones II, Douglas S., Joughin, Brian Alan, Lauffenburger, Douglas A

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Tandem phosphorylation within an intrinsically disordered region regulates ACTN4 function by Travers, Timothy, Shao, Hanshuang, Wells, Alan, Camacho, Carlos J., Joughin, Brian Alan, Lauffenburger, Douglas A

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Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs by Van de Kooij, Bert, Creixell Morera, Pau, Van Vlimmeren, Anne Elise, Joughin, Brian Alan, Yaffe, Michael B

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An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing Glioblastoma Cells by Naegle, Kristen Marie, Huang, Paul H., White, Forest M., Joughin, Brian Alan, Yaffe, Michael B, Lauffenburger, Douglas A

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Shank3 mutation in a mouse model of autism leads to changes in the S-nitroso-proteome and affects key proteins involved in vesicle release and synaptic function by Amal, Haitham, Barak, Boaz, Bhat, Vadiraja, Gong, Guanyu, Joughin, Brian Alan, Wang, Xin, Wishnok, John S., Feng, Guoping, Tannenbaum, Steven R

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ROS and Oxidative Stress Are Elevated in Mitosis during Asynchronous Cell Cycle Progression and Are Exacerbated by Mitotic Arrest by Patterson, Jesse C, Joughin, Brian Alan, Van De Kooij, Lambertus W., Lim, Daniel Cham-Chin, Yaffe, Michael B, Lauffenburger, Douglas A

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DNA repair capacity in multiple pathways predicts chemoresistance in glioblastoma multiforme by Kitange, Gaspar J., Gupta, Shiv K., Sarkaria, Jann N., Nagel, Zachary D., Joughin, Brian Alan, Chaim, Isaac Alexander, Mazzucato, Patrizia, Lauffenburger, Douglas A, Samson, Leona D

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Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation by Brubaker, Douglas, Paulo, Joao A., Sheth, Shikha, Poulin, Emily J., Popow, Olesja, Joughin, Brian Alan, Strasser, Samantha Dale, Starchenko, Alina, Gygi, Steven P., Lauffenburger, Douglas A, Haigis, Kevin M.

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A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth by Meacham, Corbin Elizabeth, Lawton, Lee N., Pritchard, Justin R., Ehrenberger, Tobias, Fenouille, Nina, Zuber, Johannes, Williams, Richard T., Young, Richard A., Soto Feliciano, Yadira Marie, Hemann, Michael, Joughin, Brian Alan

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Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data by Holland, Christian H, Tanevski, Jovan, Perales-Patón, Javier, Gleixner, Jan, Kumar, Manu Prajapati, Mereu, Elisabetta, Joughin, Brian Alan, Stegle, Oliver, Lauffenburger, Douglas A, Heyn, Holger, Szalai, Bence, Saez-Rodriguez, Julio

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Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration by Morshed, Nader, Ralvenius, William, Nott, Alexander, Watson, Lauren Ashley, Rodriguez, Felicia H, Akay, Leyla Anne, Joughin, Brian Alan, Pao, Ping-Chieh, Penney, Jay, LaRocque, Lauren, Mastroeni, Diego, Tsai, Li‐Huei, White, Forest M.

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Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma by Randall, Elizabeth C., Laramy, Janice K., Kim, Minjee, Roos, Alison, Calligaris, David, Regan, Michael S., Gupta, Shiv K., Mladek, Ann C., Carlson, Brett L., Johnson, Aaron J., Lu, Fa-Ke, Xie, X. Sunney, Peng, Sen, Abdelmoula, Walid M., Jackson, Pamela R., Kolluri, Aarti, Kellersberger, Katherine A., Agar, Jeffrey N., Swanson, Kristin R., Tran, Nhan L., Elmquist, William F., Sarkaria, Jann N., Agar, Nathalie Y. R., Emdal, Kristina Bennet, Joughin, Brian Alan, Reddy, Raven J., Lauffenburger, Douglas A, White, Forest M.

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Tissue-Specific Oncogenic Activity of KRASA146T by Poulin, Emily J., Bera, Asim K., Lu, Jia, Lin, Yi-Jang, Strasser, Samantha Dale, Paulo, Joao A., Huang, Tannie Q., Morales, Carolina, Yan, Wei, Cook, Joshua, Nowak, Jonathan A., Brubaker, Douglas K., Joughin, Brian Alan, Johnson, Christian W., DeStefanis, Rebecca A., Ghazi, Phaedra C., Gondi, Sudershan, Wales, Thomas E., Iacob, Roxana E., Bogdanova, Lana, Gierut, Jessica J., Li, Yina, Engen, John R., Perez-Mancera, Pedro A., Braun, Benjamin S., Gygi, Steven P., Lauffenburger, Douglas A, Westover, Kenneth D., Haigis, Kevin M.

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