Higher testosterone is associated with open-angle glaucoma in women: a genetic predisposition? by Joëlle E. Vergroesen, Adem Kaynak, Elif Aribas, Maryam Kavousi, Joyce B. J. van Meurs, Caroline C. W. Klaver, Wishal D. Ramdas

Get full text

Multi-Omics Analysis Reveals MicroRNAs Associated With Cardiometabolic Traits by Michelle M. J. Mens, Silvana C. E. Maas, Silvana C. E. Maas, Jaco Klap, Gerrit Jan Weverling, Paul Klatser, Just P. J. Brakenhoff, Joyce B. J. van Meurs, Joyce B. J. van Meurs, André G. Uitterlinden, André G. Uitterlinden, M. Arfan Ikram, Maryam Kavousi, Mohsen Ghanbari

Get full text

Phenotype prediction using biologically interpretable neural networks on multi-cohort multi-omics data by Arno van Hilten, Jeroen van Rooij, BIOS consortium, M. Arfan Ikram, Wiro J. Niessen, Joyce. B. J. van Meurs, Gennady V. Roshchupkin

Get full text

Dissecting the association of autophagy-related genes with cardiovascular diseases and intermediate vascular traits: A population-based approach. by Eliana Portilla-Fernandez, Mohsen Ghanbari, Joyce B J van Meurs, A H Jan Danser, Oscar H Franco, Taulant Muka, Anton Roks, Abbas Dehghan

Get full text

Differentially methylated regions in T cells identify kidney transplant patients at risk for de novo skin cancer by Fleur S. Peters, Annemiek M. A. Peeters, Pooja R. Mandaviya, Joyce B. J. van Meurs, Leo J. Hofland, Jacqueline van de Wetering, Michiel G. H. Betjes, Carla C. Baan, Karin Boer

Get full text

Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies by Jeroen van Rooij, Pooja R. Mandaviya, Annique Claringbould, Janine F. Felix, Jenny van Dongen, Rick Jansen, Lude Franke, BIOS consortium, Peter A. C. ’t Hoen, Bas Heijmans, Joyce B. J. van Meurs

Get full text

Differential expression analysis of osteoarthritic femoral head bone fragments uncovers underlying transcriptomic determinants by Vid Prijatelj, Sjur Reppe, Matthew Dietz, Carolina M. Medina-Gomez, Joost A. Verlouw, Cindy G. Boer, Joyce B.J. van Meurs, Andre J. van Wijnen, Kaare M. Gautvik, Eppo B. Wolvius, Fernando Rivadeneira

Get full text

Gut microbiome-wide association study of depressive symptoms by Djawad Radjabzadeh, Jos A. Bosch, André G. Uitterlinden, Aeilko H. Zwinderman, M. Arfan Ikram, Joyce B. J. van Meurs, Annemarie I. Luik, Max Nieuwdorp, Anja Lok, Cornelia M. van Duijn, Robert Kraaij, Najaf Amin

Get full text

A comprehensive study of genetic regulation and disease associations of plasma circulatory microRNAs using population-level data by Rima Mustafa, Michelle M. J. Mens, Arno van Hilten, Jian Huang, Gennady Roshchupkin, Tianxiao Huan, Linda Broer, Joyce B. J. van Meurs, Paul Elliott, Daniel Levy, M. Arfan Ikram, Marina Evangelou, Abbas Dehghan, Mohsen Ghanbari

Get full text

Intestinal microbiome composition and its relation to joint pain and inflammation by Cindy G. Boer, Djawad Radjabzadeh, Carolina Medina-Gomez, Sanzhima Garmaeva, Dieuwke Schiphof, Pascal Arp, Thomas Koet, Alexander Kurilshikov, Jingyuan Fu, M. Arfan Ikram, Sita Bierma-Zeinstra, André G. Uitterlinden, Robert Kraaij, Alexandra Zhernakova, Joyce B. J. van Meurs

Get full text

Genome-wide transcriptome study using deep RNA sequencing for myocardial infarction and coronary artery calcification by Xiaoling Zhang, Jeroen G. J. van Rooij, Yoshiyuki Wakabayashi, Shih-Jen Hwang, Yanqin Yang, Mohsen Ghanbari, Daniel Bos, BIOS Consortium, Daniel Levy, Andrew D. Johnson, Joyce B. J. van Meurs, Maryam Kavousi, Jun Zhu, Christopher J. O’Donnell

Get full text

Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference by Paul J. Hop, René Luijk, Lucia Daxinger, Maarten van Iterson, Koen F. Dekkers, Rick Jansen, BIOS Consortium, Joyce B. J. van Meurs, Peter A. C. ’t Hoen, M. Arfan Ikram, Marleen M. J. van Greevenbroek, Dorret I. Boomsma, P. Eline Slagboom, Jan H. Veldink, Erik W. van Zwet, Bastiaan T. Heijmans

Get full text

Accelerated menopausal changes as human disease model ‘FOCUM’ for the development of osteoarthritis and other degenerative disorders: protocol for a prospective cohort study by Sita M A Bierma-Zeinstra, Edwin H G Oei, Robert-Jan de Vos, Maryam Kavousi, Erik Lubberts, Dieuwke Schiphof, Joyce B J van Meurs, P Koen Bos, Eveline Molendijk, M Carola Zillikens, Bram C J van der Eerden, Boris W V Schouten, Mariëlla I B de Rooij-Duran

Get full text

Plasma biomarkers of endothelial dysfunction and cognition: an IPD meta-analysis of cross- sectional data from 9,344 individuals from seven Dutch cohorts by Magdalena Beran, Willemijn J. Jansen, Julie E. Oomens, Justine E.F. Moonen, Pieter Jelle Visser, Martijn A. Huisman, Almar A.L. Kok, Astrid C.J. Nooyens, W.M. Monique Verschuren, Coen D.A. Stehouwer, Casper Schalkwijk, Sebastian Köhler, Martin van Boxtel, Marian Beekman, P. Eline Slagboom, Frank J. Wolters, M. Arfan Ikram, Costanza L. Vallerga, Joyce B.J. van Meurs, Mohsen Ghanbari, Jet M.J. Vonk, Mirjam I. Geerlings, Thomas T. van Sloten, Miranda T. Schram

Get full text

Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis by Amena Keshawarz, Roby Joehanes, Jiantao Ma, Gha Young Lee, Ricardo Costeira, Pei-Chien Tsai, Olatz M. Masachs, Jordana T. Bell, Rory Wilson, Barbara Thorand, Juliane Winkelmann, Annette Peters, Jakob Linseisen, Melanie Waldenberger, Terho Lehtimäki, Pashupati P. Mishra, Mika Kähönen, Olli Raitakari, Mika Helminen, Carol A. Wang, Phillip E. Melton, Rae-Chi Huang, Craig E. Pennell, Therese A. O’Sullivan, Carolina Ochoa-Rosales, Trudy Voortman, Joyce B.J. van Meurs, Kristin L. Young, Misa Graff, Yujie Wang, Douglas P. Kiel, Caren E. Smith, Paul F. Jacques, Daniel Levy

Get full text

Association analysis between an epigenetic alcohol risk score and blood pressure by Helena Bui, Amena Keshawarz, Mengyao Wang, Mikyeong Lee, Scott M. Ratliff, Lisha Lin, Kira S. Birditt, Jessica D. Faul, Annette Peters, Christian Gieger, Thomas Delerue, Sharon L. R. Kardia, Wei Zhao, Xiuqing Guo, Jie Yao, Jerome I. Rotter, Yi Li, Xue Liu, Dan Liu, Juliana F. Tavares, Gökhan Pehlivan, Monique M. B. Breteler, Irma Karabegovic, Carolina Ochoa-Rosales, Trudy Voortman, Mohsen Ghanbari, Joyce B. J. van Meurs, Mohamed Kamal Nasr, Marcus Dörr, Hans J. Grabe, Stephanie J. London, Alexander Teumer, Melanie Waldenberger, David R. Weir, Jennifer A. Smith, Daniel Levy, Jiantao Ma, Chunyu Liu

Get full text

Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study. by Stuart H Ralston, André G Uitterlinden, Maria Luisa Brandi, Susana Balcells, Bente L Langdahl, Paul Lips, Roman Lorenc, Barbara Obermayer-Pietsch, Serena Scollen, Mariona Bustamante, Lise Bjerre Husted, Alisoun H Carey, Adolfo Diez-Perez, Alison M Dunning, Alberto Falchetti, Elzbieta Karczmarewicz, Marcin Kruk, Johannes P T M van Leeuwen, Joyce B J van Meurs, Jon Mangion, Fiona E A McGuigan, Leonardo Mellibovsky, Francesca del Monte, Huibert A P Pols, Jonathan Reeve, David M Reid, Wilfried Renner, Fernando Rivadeneira, Natasja M van Schoor, Rachael E Sherlock, John P A Ioannidis, GENOMOS Investigators

Get full text

Correction: Large-Scale Evidence for the Effect of the Sp1 Polymorphism on Osteoporosis Outcomes: The GENOMOS Study. by Stuart H Ralston, André G Uitterlinden, Maria Luisa Brandi, Susana Balcells, Bente L Langdahl, Paul Lips, Roman Lorenc, Barbara Obermayer-Pietsch, Serena Scollen, Mariona Bustamante, Lise Bjerre Husted, Alisoun H Carey, Adolfo Diez-Perez, Alison M Dunning, Alberto Falchetti, Elzbieta Karczmarewicz, Marcin Kruk, Johannes P. T. M van Leeuwen, Joyce B. J van Meurs, Jon Mangion, Fiona E. A McGuigan, Leonardo Mellibovsky, Francesca del Monte, Huibert A. P Pols, Jonathan Reeve, David M Reid, Wilfried Renner, Fernando Rivadeneira, Natasja M van Schoor, Rachael E Sherlock, John P. A Ioannidis

Get full text

Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain. by Pradeep Suri, Melody R Palmer, Yakov A Tsepilov, Maxim B Freidin, Cindy G Boer, Michelle S Yau, Daniel S Evans, Andrea Gelemanovic, Traci M Bartz, Maria Nethander, Liubov Arbeeva, Lennart Karssen, Tuhina Neogi, Archie Campbell, Dan Mellstrom, Claes Ohlsson, Lynn M Marshall, Eric Orwoll, Andre Uitterlinden, Jerome I Rotter, Gordan Lauc, Bruce M Psaty, Magnus K Karlsson, Nancy E Lane, Gail P Jarvik, Ozren Polasek, Marc Hochberg, Joanne M Jordan, Joyce B J Van Meurs, Rebecca Jackson, Carrie M Nielson, Braxton D Mitchell, Blair H Smith, Caroline Hayward, Nicholas L Smith, Yurii S Aulchenko, Frances M K Williams

Get full text

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis. by Martha C Castaño-Betancourt, Dan S Evans, Yolande F M Ramos, Cindy G Boer, Sarah Metrustry, Youfang Liu, Wouter den Hollander, Jeroen van Rooij, Virginia B Kraus, Michelle S Yau, Braxton D Mitchell, Kenneth Muir, Albert Hofman, Michael Doherty, Sally Doherty, Weiya Zhang, Robert Kraaij, Fernando Rivadeneira, Elizabeth Barrett-Connor, Rose A Maciewicz, Nigel Arden, Rob G H H Nelissen, Margreet Kloppenburg, Joanne M Jordan, Michael C Nevitt, Eline P Slagboom, Deborah J Hart, Floris Lafeber, Unnur Styrkarsdottir, Eleftheria Zeggini, Evangelos Evangelou, Tim D Spector, Andre G Uitterlinden, Nancy E Lane, Ingrid Meulenbelt, Ana M Valdes, Joyce B J van Meurs

Get full text