765 The first-in-class small molecule TREX1 inhibitor CPI-381 demonstrates type I IFN induction and sensitization of tumors to immune checkpoint blockade by Jonathan Wilson, Lei Cui, Costa Salojin, Anna Gardberg, Valerie Vivat, Jeffrey Lauer, Nico Cantone, Jacob Stuckey, Florence Poy, Ingrid Almeciga, Richard Cummings, Julian Levell, Jennifer Rocnik, Patrick Trojer