Non-Operative Management of Patients with Rectal Cancer: Lessons Learnt from the OPRA Trial by Paolo Goffredo, Felipe F. Quezada-Diaz, Julio Garcia-Aguilar, J. Joshua Smith

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Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal by Li Du, Yi-Jia Li, Marwan Fakih, Rebecca L. Wiatrek, Marjun Duldulao, Zhenbin Chen, Peiguo Chu, Julio Garcia-Aguilar, Yuan Chen

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A SMAD4‐modulated gene profile predicts disease‐free survival in stage II and III colorectal cancer by Bryan C. Szeglin, Chao Wu, Michael R. Marco, Hyun Sung Park, Zeda Zhang, Bing Zhang, Julio Garcia‐Aguilar, R. Daniel Beauchamp, X. Steven Chen, J. Joshua Smith

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Pathological Evaluation of Rectal Cancer Specimens Using Micro-Computed Tomography by Masao Yoshida, Emine Cesmecioglu, Canan Firat, Hirotsugu Sakamoto, Alexei Teplov, Noboru Kawata, Peter Ntiamoah, Takashi Ohnishi, Kareem Ibrahim, Efsevia Vakiani, Julio Garcia-Aguilar, Meera Hameed, Jinru Shia, Yukako Yagi

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Rectal Cancer after Prostate Radiation: A Complex and Controversial Disease by Dana M. Omer, Hannah M. Thompson, Floris S. Verheij, Jonathan B. Yuval, Roni Rosen, Nathalie R. A. Beets, Anisha Luthra, Paul B. Romesser, Philip B. Paty, Julio Garcia-Aguilar, Francisco Sanchez-Vega

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Quality of life and function after rectal cancer surgery with and without sphincter preservation by Emmanouil P. Pappou, Larissa K. Temple, Sujata Patil, J. Joshua Smith, Iris H. Wei, Garrett M. Nash, José G. Guillem, Maria Widmar, Martin R. Weiser, Philip B. Paty, Deborah Schrag, Julio Garcia-Aguilar

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Quantitative assessment of tumor-infiltrating lymphocytes in mismatch repair proficient colon cancer by Rosa M. Jimenez-Rodriguez, Sujata Patil, Ajaratu Keshinro, Jinru Shia, Efsevia Vakiani, Zsofia Stadler, Neil H. Segal, Rona Yaeger, Tsuyoshi Konishi, Yoshifumi Shimada, Maria Widmar, Iris Wei, Emmanouil Pappou, J. Joshua Smith, Garrett Nash, Philip Paty, Julio Garcia-Aguilar, Martin R. Weiser

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KRAS mutant rectal cancer cells interact with surrounding fibroblasts to deplete the extracellular matrix by Jin K. Kim, Michael R. Marco, Seo‐Hyun Choi, Xuan Qu, Chin‐Tung Chen, Moshe Elkabets, Lauren Fairchild, Oliver Chow, Francisco M. Barriga, Lukas E. Dow, Kevin O’Rourke, Bryan Szeglin, Dmitry Yarilin, Sho Fujisawa, Katia Manova‐Todorova, Philip B. Paty, Jinru Shia, Christina Leslie, J. Joshua Smith, Scott Lowe, Raphael Pelossof, Francisco Sanchez‐Vega, Julio Garcia‐Aguilar

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Factors Associated With Premature Ovarian Insufficiency in Young Women With Locally Advanced Rectal Cancer Treated With Pelvic Radiation Therapy by Lara Hilal, MD, Andrea Cercek, MD, John Navilio, CMD, Meier Hsu, MS, Zhigang Zhang, PhD, Paul Brady, BS, Abraham J. Wu, MD, Marsha Reyngold, MD, PhD, John J. Cuaron, MD, Paul B. Romesser, MD, Melissa Zinovoy, MD, Maliha Nusrat, MD, MS, Emmanouil Pappou, MD, PhD, FACS, FASCRS, Maria LaGratta, MD, Julio Garcia-Aguilar, MD, PhD, Philip Paty, MD, Nadeem Abu-Rustum, MD, FACOG, FACS, Mario M. Leitao, MD, FACOG, FACS, Christopher H. Crane, MD, Carla Hajj, MD

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