Coronary artery disease-related genetic variant on chromosome 10q11 is associated with carotid intima-media thickness and atherosclerosis. by Kiechl, S, Laxton, R, Xiao, Q, Hernesniemi, J, Raitakari, O, Kähönen, M, Mayosi, B, Jula, A, Moilanen, L, Willeit, J, Watkins, H, Samani, N, Lehtimäki, T, Keavney, B, Xu, Q, Ye, S

Metabolic profiling of angiopoietin-like protein 3 and 4 inhibition: a drug-target Mendelian randomization analysis by Wang, Q, Oliver-Williams, C, Raitakari, OT, Viikari, J, Lehtimäki, T, Kähönen, M, Järvelin, M-R, Salomaa, V, Perola, M, Danesh, J, Kettunen, J, Butterworth, AS, Holmes, MV, Ala-Korpela, M

Apolipoprotein A-I concentrations and risk of coronary artery disease: A Mendelian randomization study by Karjalainen, MK, Holmes, MV, Wang, Q, Anufrieva, O, Kähönen, M, Lehtimäki, T, Havulinna, AS, Kristiansson, K, Salomaa, V, Perola, M, Viikari, JS, Raitakari, OT, Järvelin, M-R, Ala-Korpela, M, Kettunen, J

Prevalenceimplications of the 2017 American Academy of Pediatrics Hypertension Guideline and associations with adult hypertension by Khoury, M, Khoury, P, Bazzano, L, Burns, TL, Daniels, S, Dwyer, T, Ikonen, J, Jacobs, DR, Juonala, M, Kähönen, M, Prineas, R, Raitakari, OT, Steinberger, J, Venn, A, Viikari, J, Woo, JG, Sinaiko, A, Urbina, EM

Childhood/adolescent smoking and adult smoking and cessation: The International Childhood Cardiovascular Cohort (i3C) Consortium by Hu, T, Gall, SL, Widome, R, Bazzano, LA, Burns, TL, Daniels, SR, Dwyer, T, Ikonen, J, Juonala, M, Kähönen, M, Prineas, RJ, Raitakari, O, Sinaiko, AR, Steinberger, J, Urbina, EM, Venn, A, Viikari, J, Woo, JG, Jacobs, DR

Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke by Seppälä, I, Kleber, M, Bevan, S, Lyytikäinen, L, Oksala, N, Hernesniemi, J, Mäkelä, K, Rothwell, P, Sudlow, C, Dichgans, M, Mononen, N, Vlachopoulou, E, Sinisalo, J, Delgado, G, Laaksonen, R, Koskinen, T, Scharnagl, H, Kähönen, M, Markus, H, März, W, Lehtimäki, T

Distinct variants at LIN28B influence growth in height from birth to adulthood. by Widén, E, Ripatti, S, Cousminer, D, Surakka, I, Lappalainen, T, Järvelin, MR, Eriksson, J, Raitakari, O, Salomaa, V, Sovio, U, Hartikainen, A, Pouta, A, McCarthy, M, Osmond, C, Kajantie, E, Lehtimäki, T, Viikari, J, Kähönen, M, Tyler-Smith, C, Freimer, N, Hirschhorn, J, Peltonen, L, Palotie, A

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. by Cousminer, D, Stergiakouli, E, Berry, D, Ang, W, Groen-Blokhuis, M, Körner, A, Siitonen, N, Ntalla, I, Marinelli, M, Perry, JR, Kettunen, J, Jansen, R, Surakka, I, Timpson, N, Ring, S, Mcmahon, G, Power, C, Wang, C, Kähönen, M, Viikari, J, Lehtimäki, T, Middeldorp, C, Hulshoff Pol, H, Neef, M, Weise, S

Genome-wide association study identifies multiple loci influencing human serum metabolite levels. by Kettunen, J, Tukiainen, T, Sarin, A, Ortega-Alonso, A, Tikkanen, E, Lyytikäinen, L, Kangas, A, Soininen, P, Würtz, P, Silander, K, Dick, D, Rose, R, Savolainen, M, Viikari, J, Kähönen, M, Lehtimäki, T, Pietiläinen, K, Inouye, M, McCarthy, M, Jula, A, Eriksson, J, Raitakari, O, Salomaa, V, Kaprio, J, Järvelin, MR

Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants by Zhou, A, Taylor, AE, Karhunen, V, Zhan, Y, Rovio, SP, Lahti, J, Sjögren, P, Byberg, L, Lyall, DM, Auvinen, J, Lehtimäki, T, Kähönen, M, Hutri-Kähönen, N, Perälä, MM, Michaëlsson, K, Mahajan, A, Lind, L, Power, C, Eriksson, JG, Raitakari, OT, Hägg, S, Pedersen, NL, Veijola, J, Järvelin, M-R, Munafò, MR, Ingelsson, E, Llewellyn, DJ, Hyppönen, E

Genome-wide association study identifies multiple loci influencing human serum metabolite levels by Kettunen, J, Tukiainen, T, Sarin, A, Ortega-Alonso, A, Tikkanen, E, Lyytikäinen, L, Kangas, A, Soininen, P, Würtz, P, Silander, K, Dick, D, Rose, R, Savolainen, M, Viikari, J, Kähönen, M, Lehtimäki Terho, J, Pietil Currency Signinen, K, Inouye, M, McCarthy, M, Jula, A, Eriksson, J, Raitakari, O, Salomaa, V, Kaprio, J, J Currency Signrvelin, M

Refining attention-deficit/hyperactivity disorder and autism spectrum disorder genetic loci by integrating summary data from genome-wide association, gene expression, and DNA methy... by Hammerschlag, AR, Byrne, EM, Agbessi, M, Ahsan, H, Alves, I, Andiappan, A, Arindrarto, W, Awadalla, P, Battle, A, Beutner, F, Bonder, MJ, Boomsma, DI, Christiansen, M, Claringbould, A, Deelen, P, Esko, T, Favé, MJ, Franke, L, Frayling, T, Gharib, SA, Gibson, G, Heijmans, BT, Hemani, G, Jansen, R, Kähönen, M, Kalnapenkis, A, Kasela, S, Kettunen, J, Kim, Y, Kirsten, H, Kovacs, P, Krohn, K, Kronberg-Guzman, J, Kukushkina, V, Kutalik, Z, Lee, B, Lehtimäki, T, Loeffler, M, Marigorta, UM, Mei, H, Milani, L, Montgomery, GW, Müller-Nurasyid, M, Nauck, M, Nivard, M, Penninx, B, Perola, M, Pervjakova, N, Pierce, BL, Powell, J, van Duijn, CM, Et al.

Genome-wide characterization of circulating metabolic biomarkers by Karjalainen, MK, Karthikeyan, S, Oliver-Williams, C, Sliz, E, Allara, E, Fung, WT, Surendran, P, Zhang, W, Jousilahti, P, Kristiansson, K, Salomaa, V, Goodwin, M, Hughes, DA, Boehnke, M, Fernandes Silva, L, Yin, X, Mahajan, A, Neville, MJ, van Zuydam, NR, de Mutsert, R, Li-Gao, R, Mook-Kanamori, DO, Demirkan, A, Liu, J, Noordam, R, Trompet, S, Chen, Z, Kartsonaki, C, Li, L, Lin, K, Hagenbeek, FA, Hottenga, JJ, Pool, R, Ikram, MA, van Meurs, J, Haller, T, Milaneschi, Y, Kähönen, M, Mishra, PP, Joshi, PK, Macdonald-Dunlop, E, Mangino, M, Zierer, J, Acar, IE, Hoyng, CB, Lechanteur, YTE, Franke, L, Kurilshikov, A, Zhernakova, A, Beekman, M, Walters, RG, Karpe, F, McCarthy, MI, van Duijn, C, Kettunen, J

Genetic determinants of serum testosterone concentrations in men. by Ohlsson, C, Wallaschofski, H, Lunetta, K, Stolk, L, Perry, JR, Koster, A, Petersen, A, Eriksson, J, Lehtimäki, T, Huhtaniemi, I, Hammond, G, Maggio, M, Coviello, A, Ferrucci, L, Heier, M, Hofman, A, Holliday, K, Jansson, J, Kähönen, M, Karasik, D, Karlsson, M, Kiel, D, Liu, Y, Ljunggren, O, Lorentzon, M, Lyytikäinen, L, Meitinger, T, Mellström, D, Melzer, D, Miljkovic, I, Nauck, M, Nilsson, M, Penninx, B, Pye, SR, Vasan, R, Reincke, M, Rivadeneira, F, Tajar, A, Teumer, A, Uitterlinden, A, Ulloor, J, Viikari, J, Völker, U, Völzke, H, Wichmann, H, Wu, T, Zhuang, W, Ziv, E, Wu, F, Raitakari, O, Eriksson, A, Bidlingmaier, M, Harris, T, Murray, A, de Jong, F, Murabito, J, Bhasin, S, Vandenput, L, Haring, R

No association of coronary artery disease with x-chromosomal variants in comprehensive international meta-analysis by Loley, C, Alver, M, Assimes, T, Bjonnes, A, Goel, A, Gustafsson, S, Hernesniemi, J, Hopewell, J, Kanoni, S, Kleber, M, Lau, K, Lu, Y, Lyytikäinen, L, Nelson, C, Nikpay, M, Qu, L, Salfati, E, Scholz, M, Tukiainen, T, Willenborg, C, Won, H, Zeng, L, Zhang, W, Anand, S, Beutner, F, Bottinger, E, Clarke, R, Dedoussis, G, Do, R, Esko, T, Eskola, M, Farrall, M, Gauguier, D, Giedraitis, V, Granger, C, Hall, A, Hamsten, A, Hazen, S, Huang, J, Kähönen, M, Kyriakou, T, Laaksonen, R, Lind, L, Lindgren, C, Magnusson, P, Marouli, E, Mihailov, E, Morris, A, Nikus, K, Pedersen, N, Rallidis, L, Salomaa, V, Shah, S, Stewart, A, Thompson, J, Zalloua, P, Chambers, J, Collins, R, Ingelsson, E, Iribarren, C, Karhunen, P, Kooner, J, Lehtimäki, T, Loos, R, März, W, McPherson, R, Metspalu, A, Reilly, M, Ripatti, S, Sanghera, D, Thiery, J, Watkins, H, Deloukas, P, Kathiresan, S, Samani, N, Schunkert, H, Erdmann, J, König, I

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. by Surakka, I, Isaacs, A, Karssen, L, Laurila, P, Middelberg, R, Tikkanen, E, Ried, J, Lamina, C, Mangino, M, Igl, W, Hottenga, J, Lagou, V, van der Harst, P, Mateo Leach, I, Esko, T, Kutalik, Z, Wainwright, N, Struchalin, M, Sarin, A, Kangas, A, Viikari, J, Perola, M, Rantanen, T, Petersen, A, Soininen, P, Johansson, A, Soranzo, N, Heath, A, Papamarkou, T, Prokopenko, I, Tönjes, A, Kronenberg, F, Döring, A, Rivadeneira, F, Montgomery, G, Whitfield, J, Kähönen, M, Lehtimäki, T, Freimer, N, Willemsen, G, de Geus, E, Palotie, A, Sandhu, MS, Waterworth, D, Metspalu, A, Stumvoll, M, Uitterlinden, A, Jula, A, Navis, G, Wijmenga, C, Wolffenbuttel, B, Taskinen, MR, Ala-Korpela, M, Kaprio, J, Kyvik, K, Boomsma, D, Pedersen, N, Gyllensten, U, Wilson, J, Rudan, I, Campbell, H, Pramstaller, P, Spector, T, Witteman, J, Eriksson, J, Salomaa, V, Oostra, B, Raitakari, O, Wichmann, H, Gieger, C, Järvelin, MR, Martin, N, Hofman, A, McCarthy, M, Peltonen, L, van Duijn, C, Aulchenko, Y, Ripatti, S

Evidence of inbreeding depression on human height. by McQuillan, R, Eklund, N, Pirastu, N, Kuningas, M, McEvoy, B, Esko, T, Corre, T, Davies, G, Kaakinen, M, Lyytikäinen, L, Kristiansson, K, Havulinna, A, Gögele, M, Vitart, V, Tenesa, A, Aulchenko, Y, Hayward, C, Johansson, A, Boban, M, Ulivi, S, Robino, A, Boraska, V, Igl, W, Wild, S, Zgaga, L, Amin, N, Theodoratou, E, Polašek, O, Girotto, G, Lopez, L, Sala, C, Lahti, J, Laatikainen, T, Prokopenko, I, Kals, M, Viikari, J, Yang, J, Pouta, A, Estrada, K, Hofman, A, Freimer, N, Martin, N, Kähönen, M, Milani, L, Heliövaara, M, Vartiainen, E, Räikkönen, K, Masciullo, C, Starr, J, Hicks, A, Esposito, L, Kolčić, I, Farrington, S, Oostra, B, Zemunik, T, Campbell, H, Kirin, M, Pehlic, M, Faletra, F, Porteous, D, Pistis, G, Widén, E, Salomaa, V, Koskinen, S, Fischer, K, Lehtimäki, T, Heath, A, McCarthy, M, Rivadeneira, F, Montgomery, G, Tiemeier, H, Hartikainen, A, Madden, P, d'Adamo, P, Hastie, N, Gyllensten, U, Wright, A, van Duijn, C, Dunlop, M, Rudan, I, Gasparini, P, Pramstaller, P, Deary, I, Toniolo, D, Eriksson, J, Jula, A, Raitakari, O, Metspalu, A, Perola, M, Järvelin, MR, Uitterlinden, A, Visscher, P, Wilson, J

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. by Coviello, A, Haring, R, Wellons, M, Vaidya, D, Lehtimäki, T, Keildson, S, Lunetta, K, He, C, Fornage, M, Lagou, V, Mangino, M, Onland-Moret, N, Chen, B, Eriksson, J, Garcia, M, Liu, Y, Koster, A, Lohman, K, Lyytikäinen, L, Petersen, A, Prescott, J, Stolk, L, Vandenput, L, Wood, A, Zhuang, W, Ruokonen, A, Hartikainen, A, Pouta, A, Bandinelli, S, Biffar, R, Brabant, G, Cox, D, Chen, Y, Cummings, S, Ferrucci, L, Gunter, M, Hankinson, SE, Martikainen, H, Hofman, A, Homuth, G, Illig, T, Jansson, J, Johnson, A, Karasik, D, Karlsson, M, Kettunen, J, Kiel, D, Kraft, P, Liu, J, Ljunggren, Ö, Lorentzon, M, Maggio, M, Markus, MR, Mellström, D, Miljkovic, I, Mirel, D, Nelson, S, Morin Papunen, L, Peeters, P, Prokopenko, I, Raffel, L, Reincke, M, Reiner, A, Rexrode, K, Rivadeneira, F, Schwartz, S, Siscovick, D, Soranzo, N, Stöckl, D, Tworoger, S, Uitterlinden, A, Gils, v, Vasan, R, Wichmann, H, Zhai, G, Bhasin, S, Bidlingmaier, M, Chanock, S, De Vivo, I, Harris, T, Hunter, D, Kähönen, M, Liu, S, Ouyang, P, Spector, T, van der Schouw, Y, Viikari, J, Wallaschofski, H, McCarthy, M, Frayling, T, Murray, A, Franks, S, Järvelin, MR, de Jong, F, Raitakari, O, Teumer, A, Ohlsson, C, Murabito, J, Perry, JR

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets by Wain, L, Shrine, N, Artigas, M, Erzurumluoglu, A, Noyvert, B, Bossini-Castillo, L, Obeidat, M, Henry, A, Portelli, M, Hall, R, Billington, C, Rimington, T, Fenech, A, John, C, Blake, T, Jackson, V, Allen, R, Prins, B, Understanding Society Scientific Group, Campbell, A, Porteous, D, Jarvelin, M, Wielscher, M, James, A, Hui, J, Wareham, N, Zhao, J, Wilson, J, Joshi, P, Stubbe, B, Rawal, R, Schulz, H, Imboden, M, Probst-Hensch, N, Karrasch, S, Gieger, C, Deary, I, Harris, S, Marten, J, Rudan, I, Enroth, S, Gyllensten, U, Kerr, S, Polasek, O, Kähönen, M, Surakka, I, Vitart, V, Hayward, C, Lehtimäki, T, Raitakari, O, Evans, D, Henderson, A, Pennell, C, Wang, C, Sly, P, Wan, E, Busch, R, Hobbs, B, Litonjua, A, Sparrow, D, Gulsvik, A, Bakke, P, Crapo, J, Beaty, T, Hansel, N, Mathias, R, Ruczinski, I, Barnes, K, Bossé, Y, Joubert, P, van den Berge, M, Brandsma, C, Paré, P, Sin, D, Nickle, D, Hao, K, Gottesman, O, Dewey, F, Bruse, S, Carey, D, Kirchner, H, Geisinger-Regeneron DiscovEHR Collaboration, Jonsson, S, Thorleifsson, G, Jonsdottir, I, Gislason, T, Stefansson, K, Schurmann, C, Nadkarni, G, Bottinger, E, Loos, R, Walters, R, Chen, Z, Millwood, I, Vaucher, J, Kurmi, O, Li, L, Hansell, A, Brightling, C, Zeggini, E, Cho, M, Silverman, E, Sayers, I, Trynka, G, Morris, A, Strachan, D, Hall, I, Tobin, M

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. by Jiang, X, O'Reilly, PF, Aschard, H, Hsu, Y-H, Richards, JB, Dupuis, J, Ingelsson, E, Karasik, D, Pilz, S, Berry, D, Kestenbaum, B, Zheng, J, Luan, J, Sofianopoulou, E, Streeten, EA, Albanes, D, Lutsey, PL, Yao, L, Tang, W, Econs, MJ, Wallaschofski, H, Völzke, H, Zhou, A, Power, C, McCarthy, MI, Michos, ED, Boerwinkle, E, Weinstein, SJ, Freedman, ND, Huang, W-Y, Van Schoor, NM, van der Velde, N, Groot, LCPGMD, Booth, SL, Vasan, RS, Liu, C-T, Zhou, Y, Ripatti, S, Ohlsson, C, Eriksson, JG, Shea, MK, Houston, DK, Kritchevsky, SB, Liu, Y, Lohman, KK, Ferrucci, L, Peacock, M, Gieger, C, Beekman, M, Slagboom, E, Deelen, J, Heemst, DV, Kleber, ME, März, W, de Boer, IH, Wood, AC, Rotter, JI, Rich, SS, Robinson-Cohen, C, Heijer, M, Jarvelin, M-R, Cavadino, A, Joshi, PK, Wilson, JF, Hayward, C, Lind, L, Michaëlsson, K, Trompet, S, Zillikens, MC, Uitterlinden, AG, Rivadeneira, F, Broer, L, Zgaga, L, Campbell, H, Theodoratou, E, Farrington, SM, Timofeeva, M, Dunlop, MG, Valdes, AM, Tikkanen, E, Lehtimäki, T, Lyytikäinen, L-P, Kähönen, M, Raitakari, OT, Mikkilä, V, Ikram, MA, Sattar, N, Jukema, JW, Wareham, NJ, Langenberg, C, Forouhi, NG, Gundersen, TE, Khaw, K-T, Butterworth, AS, Danesh, J, Spector, T, Wang, TJ, Hyppönen, E, Kraft, P, Kiel, DP