DNA methylation patterns associated with oxidative stress in an ageing population by Åsa K. Hedman, Mihkel Zilmer, Johan Sundström, Lars Lind, Erik Ingelsson

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Correction: Transcriptional Profiling of Serogroup B Growing in Human Blood: An Approach to Vaccine Antigen Discovery. by Asa K. Hedman, Ming-Shi Li, Paul R. Langford, J. Simon Kroll

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Correction: Transcriptional Profiling of Serogroup B Growing in Human Blood: An Approach to Vaccine Antigen Discovery. by Åsa K. Hedman, Ming-Shi Li, Paul R. Langford, J. Simon Kroll

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Detection and monitoring of human bocavirus 1 infection by a new rapid antigen test by A.H.L. Bruning, P. Susi, H. Toivola, A. Christensen, M. Söderlund-Venermo, K. Hedman, H. Aatola, A. Zvirbliene, J.O. Koskinen

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POS-264 PATIENT PALATABILITY AND PREFERENCE STUDY OF 3 POTASSIUM BINDERS IN PATIENTS WITH CHRONIC KIDNEY DISEASE AND HYPERKALAEMIA: RATIONALE AND DESIGN OF THE APPETIZE STUDY by G. JAMES, H. Søndergaard, K. Hedman, N. Karlsson, E. Wittbrodt, I. Sabir, J. Kim, R. Allgren, G. Stjernlöf, M. Någård, H.L. Chung, J. Morris, D.C. Wheeler

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POS-329 TREATMENT PATTERNS IN CHRONIC KIDNEY DISEASE PATIENTS WITH HYPERKALEMIA: A REPORT FROM THE DISCOVER CKD RETROSPECTIVE COHORT by G. JAMES, J.J. Carrero, S. Kumar, S. Fishbane, E. Wittbrodt, E. Kanda, K. Hedman, N. Kashihara, M. Kosiborod, M. Lainscak, C. Lam, C. Pollock, P. Stenvinkel, D.C. Wheeler, R. Pecoits-Filho

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POS-328 THE BURDEN OF HYPERKALEMIA IN PATIENTS WITH CHRONIC KIDNEY DISEASE: A REPORT FROM THE DISCOVER CKD RETROSPECTIVE COHORT by G. JAMES, J.J. Carrero, S. Kumar, S. Fishbane, E. Wittbrodt, E. Kanda, K. Hedman, N. Kashihara, M. Kosiborod, M. Lainscak, C. Lam, C. Pollock, P. Stenvinkel, D.C. Wheeler, R. Pecoits-Filho

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The genetic regulation of protein expression in cerebrospinal fluid by Oskar Hansson, Atul Kumar, Shorena Janelidze, Erik Stomrud, Philip S Insel, Kaj Blennow, Henrik Zetterberg, Eric Fauman, Åsa K Hedman, Michael W Nagle, Christopher D Whelan, Denis Baird, Anders Mälarstig, Niklas Mattsson‐Carlgren

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POS-526 UNDERSTANDING THE PATIENT EXPERIENCE AND CLINICAL COURSE DURING THE INCIDENT DIALYSIS PERIOD: DESIGN AND IMPLEMENTATION OF A DOPPS CHINA STUDY by L. HENN, Z. Ni, X. Liang, M. Guedes, J. Zhao, E. Wittbrodt, F. Khan, J. Sloand, J.J. Garcia-Sanchez, K. Hedman, G. James, R. Pecoits-Filho, R. Pisoni, B. Robinson, L. Zuo

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Peripheral blood cellular dynamics of rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs by Åsa K. Hedman, Eitan Winter, Niyaz Yoosuf, Yair Benita, Louise Berg, Boel Brynedal, Lasse Folkersen, Lars Klareskog, Mateusz Maciejewski, Alexandra Sirota-Madi, Yael Spector, Daniel Ziemek, Leonid Padyukov, Shai S. Shen-Orr, Scott A. Jelinsky

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Large-scale metabolomic profiling identifies novel biomarkers for incident coronary heart disease. by Andrea Ganna, Samira Salihovic, Johan Sundström, Corey D Broeckling, Asa K Hedman, Patrik K E Magnusson, Nancy L Pedersen, Anders Larsson, Agneta Siegbahn, Mihkel Zilmer, Jessica Prenni, Johan Arnlöv, Lars Lind, Tove Fall, Erik Ingelsson

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Higher chylomicron remnants and LDL particle numbers associate with CD36 SNPs and DNA methylation sites that reduce CD36[S] by Latisha Love-Gregory, Aldi T. Kraja, Fiona Allum, Stella Aslibekyan, Åsa K. Hedman, Yanan Duan, Ingrid B. Borecki, Donna K. Arnett, Mark I. McCarthy, Panos Deloukas, Jose M. Ordovas, Paul N. Hopkins, Elin Grundberg, Nada A. Abumrad

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The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue. by Alexander W Drong, George Nicholson, Asa K Hedman, Eshwar Meduri, Elin Grundberg, Kerrin S Small, So-Youn Shin, Jordana T Bell, Fredrik Karpe, Nicole Soranzo, Tim D Spector, Mark I McCarthy, Panos Deloukas, Mattias Rantalainen, Cecilia M Lindgren, MolPAGE Consortia

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Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins by Yunzhang Wang, Robert Karlsson, Erik Lampa, Qian Zhang, Åsa K. Hedman, Malin Almgren, Catarina Almqvist, Allan F. McRae, Riccardo E. Marioni, Erik Ingelsson, Peter M. Visscher, Ian J. Deary, Lars Lind, Tiffany Morris, Stephan Beck, Nancy L. Pedersen, Sara Hägg

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Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation by Anders Mälarstig, Felix Grassmann, Leo Dahl, Marios Dimitriou, Dianna McLeod, Marike Gabrielson, Karl Smith-Byrne, Cecilia E. Thomas, Tzu-Hsuan Huang, Simon K. G. Forsberg, Per Eriksson, Mikael Ulfstedt, Mattias Johansson, Aleksandr V. Sokolov, Helgi B. Schiöth, Per Hall, Jochen M. Schwenk, Kamila Czene, Åsa K. Hedman

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Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. by Jordana T Bell, Pei-Chien Tsai, Tsun-Po Yang, Ruth Pidsley, James Nisbet, Daniel Glass, Massimo Mangino, Guangju Zhai, Feng Zhang, Ana Valdes, So-Youn Shin, Emma L Dempster, Robin M Murray, Elin Grundberg, Asa K Hedman, Alexandra Nica, Kerrin S Small, MuTHER Consortium, Emmanouil T Dermitzakis, Mark I McCarthy, Jonathan Mill, Tim D Spector, Panos Deloukas

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Extent, causes, and consequences of small RNA expression variation in human adipose tissue. by Leopold Parts, Åsa K Hedman, Sarah Keildson, Andrew J Knights, Cei Abreu-Goodger, Martijn van de Bunt, José Afonso Guerra-Assunção, Nenad Bartonicek, Stijn van Dongen, Reedik Mägi, James Nisbet, Amy Barrett, Mattias Rantalainen, Alexandra C Nica, Michael A Quail, Kerrin S Small, Daniel Glass, Anton J Enright, John Winn, MuTHER Consortium, Panos Deloukas, Emmanouil T Dermitzakis, Mark I McCarthy, Timothy D Spector, Richard Durbin, Cecilia M Lindgren

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The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. by Alexandra C Nica, Leopold Parts, Daniel Glass, James Nisbet, Amy Barrett, Magdalena Sekowska, Mary Travers, Simon Potter, Elin Grundberg, Kerrin Small, Asa K Hedman, Veronique Bataille, Jordana Tzenova Bell, Gabriela Surdulescu, Antigone S Dimas, Catherine Ingle, Frank O Nestle, Paola di Meglio, Josine L Min, Alicja Wilk, Christopher J Hammond, Neelam Hassanali, Tsun-Po Yang, Stephen B Montgomery, Steve O'Rahilly, Cecilia M Lindgren, Krina T Zondervan, Nicole Soranzo, Inês Barroso, Richard Durbin, Kourosh Ahmadi, Panos Deloukas, Mark I McCarthy, Emmanouil T Dermitzakis, Timothy D Spector, MuTHER Consortium

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Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. by Guangju Zhai, Alexander Teumer, Lisette Stolk, John R B Perry, Liesbeth Vandenput, Andrea D Coviello, Annemarie Koster, Jordana T Bell, Shalender Bhasin, Joel Eriksson, Anna Eriksson, Florian Ernst, Luigi Ferrucci, Timothy M Frayling, Daniel Glass, Elin Grundberg, Robin Haring, Asa K Hedman, Albert Hofman, Douglas P Kiel, Heyo K Kroemer, Yongmei Liu, Kathryn L Lunetta, Marcello Maggio, Mattias Lorentzon, Massimo Mangino, David Melzer, Iva Miljkovic, MuTHER Consortium, Alexandra Nica, Brenda W J H Penninx, Ramachandran S Vasan, Fernando Rivadeneira, Kerrin S Small, Nicole Soranzo, André G Uitterlinden, Henry Völzke, Scott G Wilson, Li Xi, Wei Vivian Zhuang, Tamara B Harris, Joanne M Murabito, Claes Ohlsson, Anna Murray, Frank H de Jong, Tim D Spector, Henri Wallaschofski

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Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach. by Michael M Mendelson, Riccardo E Marioni, Roby Joehanes, Chunyu Liu, Åsa K Hedman, Stella Aslibekyan, Ellen W Demerath, Weihua Guan, Degui Zhi, Chen Yao, Tianxiao Huan, Christine Willinger, Brian Chen, Paul Courchesne, Michael Multhaup, Marguerite R Irvin, Ariella Cohain, Eric E Schadt, Megan L Grove, Jan Bressler, Kari North, Johan Sundström, Stefan Gustafsson, Sonia Shah, Allan F McRae, Sarah E Harris, Jude Gibson, Paul Redmond, Janie Corley, Lee Murphy, John M Starr, Erica Kleinbrink, Leonard Lipovich, Peter M Visscher, Naomi R Wray, Ronald M Krauss, Daniele Fallin, Andrew Feinberg, Devin M Absher, Myriam Fornage, James S Pankow, Lars Lind, Caroline Fox, Erik Ingelsson, Donna K Arnett, Eric Boerwinkle, Liming Liang, Daniel Levy, Ian J Deary

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