Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation Bằng Aleksandra Levina, Kaelin D. Fleming, John E. Burke, Thomas A. Leonard

lấy văn bản

Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors Bằng Manoj K Rathinaswamy, Zied Gaieb, Kaelin D Fleming, Chiara Borsari, Noah J Harris, Brandon E Moeller, Matthias P Wymann, Rommie E Amaro, John E Burke

lấy văn bản

The middle lipin domain adopts a membrane-binding dimeric protein fold Bằng Weijing Gu, Shujuan Gao, Huan Wang, Kaelin D. Fleming, Reece M. Hoffmann, Jong Won Yang, Nimi M. Patel, Yong Mi Choi, John E. Burke, Karen Reue, Michael V. Airola

lấy văn bản

Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation Bằng Yong Mi Choi, Dalila Ajjaji, Kaelin D. Fleming, Peter P. Borbat, Meredith L. Jenkins, Brandon E. Moeller, Shaveen Fernando, Surita R. Bhatia, Jack H. Freed, John E. Burke, Abdou Rachid Thiam, Michael V. Airola

lấy văn bản

Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs Bằng Manoj K. Rathinaswamy, Meredith L. Jenkins, Benjamin R. Duewell, Xuxiao Zhang, Noah J. Harris, John T. Evans, Jordan T.B. Stariha, Udit Dalwadi, Kaelin D. Fleming, Harish Ranga-Prasad, Calvin K. Yip, Roger L. Williams, Scott D. Hansen, John E. Burke

lấy văn bản