Quantitative Contribution of IL2Rγ to the Dynamic Formation of IL2-IL2R Complexes. by Luis F Ponce, Karina García-Martínez, Kalet León

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Editor de ecuaciones para la plataforma de simulación de sistemas biológicos by Gilberto Arias Naranjo, Kalet León Monzón, Noel Moreno Lemus

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Characterizing steady states of genome-scale metabolic networks in continuous cell cultures. by Jorge Fernandez-de-Cossio-Diaz, Kalet Leon, Roberto Mulet

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La física vitae cubana. Sinopsis antes de la COVID-19 by Carlos Cabal Mirabal, Rodolfo Alfonso La Guardia, Kalet León Monzón

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The Position of EGF Deprivation in the Management of Advanced Non-Small Cell Lung Cancer by Tania Crombet Ramos, Orestes Santos Morales, Grace K. Dy, Kalet León Monzón, Agustín Lage Dávila

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HEK293 producing the extracellular domain HER1: Full datasets of continuous fermentation process and metabolites analysis by Lisandra Calzadilla, Erick Hernández, Julio Dustet, Jorge Fernandez-de-Cossio-Diaz, Kalet León, Matthias Pietzke, Alexei Vazquez, Roberto Mulet, Tammy Boggiano

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A rationally-engineered IL-2 improves the antitumor effect of anti-CD20 therapy by Ana Victoria Casadesús, Claire Deligne, Béré Kadjdiatou Diallo, Katya Sosa, Nathalie Josseaume, Circe Mesa, Kalet León, Tays Hernández, Jean-Luc Teillaud

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The antitumor effect induced by an IL-2 ‘no-alpha’ mutein depends on changes in the CD8+ T lymphocyte/Treg cell balance by Tania Carmenate, Galia Montalvo, Sum Lai Lozada, Yaretnis Rodriguez, Yaquelin Ortiz, Claudia Díaz, Janet Avellanet, Juhee Kim, Charles D. Surh, Luis Graça, Kalet León

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Modulation of CD4 T cell function via CD6-targetingResearch in context by Raquel Filipa Freitas, Afonso Basto, Silvia C.P. Almeida, Rita F. Santos, Carine M. Gonçalves, Jesus Corria-Osorio, Tânia Carvalho, Alexandre M. Carmo, Vanessa G. Oliveira, Kalet Leon, Luis Graca

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An anti-CD6 monoclonal antibody (itolizumab) reduces circulating IL-6 in severe COVID-19 elderly patients by Danay Saavedra, Ana Laura Añé-Kourí, Naivy Sánchez, Lázaro Manuel Filgueira, Julio Betancourt, Carlos Herrera, Leniel Manso, Elibet Chávez, Armando Caballero, Carlos Hidalgo, Geydi Lorenzo, Meylan Cepeda, Carmen Valenzuela, Mayra Ramos, Kalet León, Zaima Mazorra, Tania Crombet

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Potent immunomodulatory and antitumor effect of anti-CD20-IL2no-alpha tri-functional immunocytokine for cancer therapy by Ana Victoria Casadesús, Beatriz María Cruz, Wilden Díaz, Miguel Ángel González, Tania Gómez, Briandy Fernández, Addys González, Nuris Ledón, Katya Sosa, Kathleen Castro, Armando López, Claudia Plasencia, Yaima Ramírez, Jean-Luc Teillaud, Calixto Hernández, Kalet León, Tays Hernández

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NeuroEPO plus (NeuralCIM®) in mild-to-moderate Alzheimer’s clinical syndrome: the ATHENEA randomized clinical trial by Saily Sosa, Giosmany Bringas, Nelky Urrutia, Ana Ivis Peñalver, Danay López, Evelio González, Ana Fernández, Zenaida Milagros Hernández, Ariel Viña, Yamile Peña, Juan Felipe Batista, Carmen Valenzuela, Kalet León, Tania Crombet, Teresita Rodríguez, Leslie Pérez, on behalf of the ATHENEA Investigators

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Molecular Aspects Concerning the Use of the SARS-CoV‑2 Receptor Binding Domain as a Target for Preventive Vaccines by Yury Valdes-Balbin, Darielys Santana-Mederos, Françoise Paquet, Sonsire Fernandez, Yanet Climent, Fabrizio Chiodo, Laura Rodríguez, Belinda Sanchez Ramirez, Kalet Leon, Tays Hernandez, Lila Castellanos-Serra, Raine Garrido, Guang-Wu Chen, Dagmar Garcia-Rivera, Daniel G. Rivera, Vicente Verez-Bencomo

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Reposicionamiento del anticuerpo monoclonal humanizado anti-CD6 itolizumab en el tratamiento de pacientes con COVID-19 by Tania Crombet Ramos, Mayra Ramos Suzarte, Danay Saavedra Hernández, Kalet León Monzón, Julio Betancourt Cervantes, Lázaro Filgueira Morilla, Carlos J. Hidalgo Mesa, Yayquier Díaz Morales, Zaima Mazorra Herrera, Patricia Lorenzo Luaces, Carmen Valenzuela Silva, Geydi Lorenzo Monteagudo, Meyán Cepeda Portales, Armando Caballero López

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Molecular reshaping of phage-displayed Interleukin-2 at beta chain receptor interface to obtain potent super-agonists with improved developability profiles by Gertrudis Rojas, Ernesto Relova-Hernández, Annia Pérez-Riverón, Camila Castro-Martínez, Osmany Diaz-Bravo, Yanelys Cabrera Infante, Tania Gómez, Joaquín Solozábal, Ana Beatriz DíazBravo, Maren Schubert, Marlies Becker, Beatriz Pérez-Massón, Dayana Pérez-Martínez, Rydell Alvarez-Arzola, Osmany Guirola, Glay Chinea, Luis Graca, Stefan Dübel, Kalet León, Tania Carmenate

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Augmenting antibody response to EGF-depleting immunotherapy: Findings from a phase I trial of CIMAvax-EGF in combination with nivolumab in advanced stage NSCLC by Rachel Evans, Kelvin Lee, Paul K. Wallace, Mary Reid, Jason Muhitch, Askia Dozier, Circe Mesa, Patricia L. Luaces, Orestes Santos-Morales, Adrienne Groman, Carlos Cedeno, Aileen Cinquino, Daniel T. Fisher, Igor Puzanov, Mateusz Opyrchal, Christos Fountzilas, Tong Dai, Marc Ernstoff, Kristopher Attwood, Alan Hutson, Candace Johnson, Zaima Mazorra, Danay Saavedra, Kalet Leon, Agustin Lage, Tania Crombet, Grace K. Dy

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Efficacy of direct current generated by multiple-electrode arrays on F3II mammary carcinoma: experiment and mathematical modeling by Narciso Antonio Villar Goris, Jorge Luis García Rodríguez, Maraelys Morales González, Beatriz Olivares Borges, Dasha Fuentes Morales, Enaide Maine Calzado, Antonio Rafael Selva Castañeda, Leonardo Mesa Torres, Juan Ignacio Montijano, Victoriano Gustavo Sierra González, Daniel Jay Pérez, Oscar Ortiz Posada, Janet Avellanet Martínez, Arlem García Delgado, Karina García Martínez, Mayrel Labrada Mon, Kalet León Monzón, Héctor Manuel Camué Ciria, Luis Enrique Bergues Cabrales

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PREVAX: A Phase I Clinical Trial of an EGF-Based Vaccine in Moderate-to-Severe COPD Patients by Jenysbel de la C. Hernandez Reyes, Orestes Santos Morales, Laura Hernandez Moreno, Pedro Pablo Pino Alfonso, Elia Neninger Vinageras, Julia Lilliam Knigths Montalvo, Aliuska Aguilar Sosa, Amnely Gonzalez Morera, Patricia Lorenzo-Luaces Alvárez, Yadira Aguilar Venegas, Mayelin Troche Concepción, Loipa Medel Pérez, Yanela Santiesteban González, Lázara García Fernández, Lorena Regueiro Rodríguez, Amparo Macías Abrahan, Mayrel Labrada Mon, Kalet León Monzón, Danay Saavedra Hernández, Tania Crombet Ramos

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Development of a scalable single process for producing SARS-CoV-2 RBD monomer and dimer vaccine antigens by Tammy Boggiano-Ayo, Julio Palacios-Oliva, Sumlai Lozada-Chang, Ernesto Relova-Hernandez, Jose Gomez-Perez, Gonzalo Oliva, Lourdes Hernandez, Alexi Bueno-Soler, Daidee Montes de Oca, Osvaldo Mora, Roberto Machado-Santisteban, Dayana Perez-Martinez, Beatriz Perez-Masson, Yanelys Cabrera Infante, Lisandra Calzadilla-Rosado, Yaima Ramirez, Judey Aymed-Garcia, Ingrid Ruiz-Ramirez, Yamile Romero, Tania Gomez, Luis A. Espinosa, Luis Javier Gonzalez, Annia Cabrales, Osmany Guirola, Kathya Rashida de la Luz, Franciscary Pi-Estopiñan, Belinda Sanchez-Ramirez, Dagmar Garcia-Rivera, Yuri Valdes-Balbin, Gertrudis Rojas, Kalet Leon-Monzon, Eduardo Ojito-Magaz, Eugenio Hardy

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