AML-348 A phase Ib/II study of ivosidenib with venetoclax +/- azacitidine in IDH1-mutated hematologic malignancies by Lachowiez, C, Borthakur, G, Loghavi, S, Zeng, Z, Kadia, T, Masarova, L, Takahashi, K, Tippett, G, Garcia, J, Bose, P, Jabbour, E, Ravandi, F, Daver, N, Manero, GG, Vyas, P, Kantarjian, H, Konopleva, M, DiNardo, C

Safety and Clinical Activity of Mutant IDH1 Inhibitor IVOSIDENIB (IVO; AG-120) In Combination with AZACITIDINE (AZA) for Newly Diagnosed Acute Myeloid Leukemia (ND AML) by DiNardo, C, Stein, A, Stein, E, Fathi, A, Frankfurt, O, Schuh, A, Doehner, H, Martinelli, G, Patel, P, Raffoux, E, Tan, P, Zeidan, A, De Botton, S, Kantarjian, H, Stone, R, Lam, D, Wang, X, Gong, J, Kapsalis, S, Hickman, D, Zhang, V, Winkler, T, Wu, B, Vyas, P

A phase Ib/II study of ivosidenib with venetoclax ± azacitidine in IDH1-mutated myeloid malignancies by Lachowiez, CA, Loghavi, S, Zeng, Z, Tanaka, T, Kim, YJ, Uryu, H, Turkalj, S, Jakobsen, NA, Luskin, MR, Duose, DY, Tidwell, RSS, Short, NJ, Borthakur, G, Kadia, TM, Masarova, L, Tippett, GD, Bose, P, Jabbour, EJ, Ravandi, F, Daver, NG, Garcia-Manero, G, Kantarjian, H, Garcia, JS, Vyas, P, Takahashi, K, Konopleva, M, DiNardo, CD

MLL-rearranged acute lymphoblastic leukemias activate BCL-2 through H3K79 methylation and are sensitive to the BCL-2-specific antagonist ABT-199 by Benito, J, Godfrey, L, Kojima, K, Hogdal, L, Wunderlich, M, Geng, H, Marzo, I, Harutyunyan, K, Golfman, L, North, P, Kerry, J, Ballabio, E, Chonghaile, T, Gonzalo, O, Qiu, Y, Jeremias, I, Debose, L, O'Brien, E, Ma, H, Zhou, P, Jacamo, R, Park, E, Coombes, K, Zhang, N, Thomas, D, O'Brien, S, Kantarjian, H, Leverson, J, Kornblau, S, Andreeff, M, Müschen, M, Zweidler-McKay, P, Mulloy, J, Letai, A, Milne, T, Konopleva, M

AML-262 Pivekimab Sunirine (PVEK, IMGN632) triplet with azacitidine and venetoclax shows broad activity in adverse genetic subsets of relapsed/refractory acute myeloid leukemia and... by Daver, N, Montesinos, P, Aribi, A, Martinelli, G, Altman, JK, Wang, ES, Roboz, GJ, Burke, PW, Gaidano, G, Walter, RB, Thomas, X, Jeyakumar, D, DeAngelo, DJ, Erba, HP, Todisco, E, Begna, K, Advani, A, Gastaud, L, de la Fuente, A, Curti, A, Mendez, LM, Vyas, P, Boissel, N, Vey, N, Recher, C, Longval, T, Platzbecker, U, Kapp-Schwörer, S, Schliemann, C, Konopleva, M, Torres, L, Sallman, DA, Marcucci, G, Marconi, G, Kantarjian, H, Sloss, CM, Malcolm, KE, Zweidler-McKay, PA, Sweet, K