Karen Mohlke

Karen L. Mohlke is a biologist at University of North Carolina, Chapel Hill. She is known for her work in human genetics, especially in the area of diabetes research. She was one of the first researchers to use exome array genotyping. Provided by Wikipedia
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  1. 1
    Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus.

    Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus. by Marie P Fogarty, Maren E Cannon, Swarooparani Vadlamudi, Kyle J Gaulton, Karen L Mohlke

    Published 2014-09-01
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  2. 2
    Association studies with imputed variants using expectation-maximization likelihood-ratio tests.

    Association studies with imputed variants using expectation-maximization likelihood-ratio tests. by Kuan-Chieh Huang, Wei Sun, Ying Wu, Mengjie Chen, Karen L Mohlke, Leslie A Lange, Yun Li

    Published 2014-01-01
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  3. 3
    Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci

    Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci by Hannah J. Perrin, Kevin W. Currin, Swarooparani Vadlamudi, Gautam K. Pandey, Kenneth K. Ng, Martin Wabitsch, Markku Laakso, Michael I. Love, Karen L. Mohlke

    Published 2021-10-01
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  4. 4
    INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis.

    INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis. by Yan Liu, Hanna K Sanoff, Hyunsoon Cho, Christin E Burd, Chad Torrice, Karen L Mohlke, Joseph G Ibrahim, Nancy E Thomas, Norman E Sharpless

    Published 2009-01-01
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  5. 5
    Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels[S]

    Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels[S] by Ying Wu, Amanda F. Marvelle, Jin Li, Damien C. Croteau-Chonka, Alan B. Feranil, Christopher W. Kuzawa, Yun Li, Linda S. Adair, Karen L. Mohlke

    Published 2013-11-01
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  6. 6
    Liver regulatory mechanisms of noncoding variants at lipid and metabolic trait loci

    Liver regulatory mechanisms of noncoding variants at lipid and metabolic trait loci by Gautam K. Pandey, Swarooparani Vadlamudi, Kevin W. Currin, Anne H. Moxley, Jayna C. Nicholas, Jessica C. McAfee, K. Alaine Broadaway, Karen L. Mohlke

    Published 2024-04-01
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  7. 7
    Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci.

    Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci. by Hannah J Perrin, Kevin W Currin, Swarooparani Vadlamudi, Gautam K Pandey, Kenneth K Ng, Martin Wabitsch, Markku Laakso, Michael I Love, Karen L Mohlke

    Published 2021-10-01
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  8. 8
    Inferring Regulatory Networks From Mixed Observational Data Using Directed Acyclic Graphs

    Inferring Regulatory Networks From Mixed Observational Data Using Directed Acyclic Graphs by Wujuan Zhong, Li Dong, Taylor B. Poston, Toni Darville, Cassandra N. Spracklen, Di Wu, Di Wu, Karen L. Mohlke, Yun Li, Yun Li, Quefeng Li, Xiaojing Zheng, Xiaojing Zheng

    Published 2020-02-01
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  9. 9
    Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits

    Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits by Maren E. Cannon, Kevin W. Currin, Kristin L. Young, Hannah J. Perrin, Swarooparani Vadlamudi, Alexias Safi, Lingyun Song, Ying Wu, Martin Wabitsch, Markku Laakso, Gregory E. Crawford, Karen L. Mohlke

    Published 2019-08-01
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  10. 10
    Age-dependent genes in adipose stem and precursor cells affect regulation of fat cell differentiation and link aging to obesity via cellular and genetic interactions

    Age-dependent genes in adipose stem and precursor cells affect regulation of fat cell differentiation and link aging to obesity via cellular and genetic interactions by Asha Kar, Marcus Alvarez, Kristina M. Garske, Huiling Huang, Seung Hyuk T. Lee, Milena Deal, Sankha Subhra Das, Amogha Koka, Zoeb Jamal, Karen L. Mohlke, Markku Laakso, Sini Heinonen, Kirsi H. Pietiläinen, Päivi Pajukanta

    Published 2024-01-01
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  11. 11
    Pla2g12b drives expansion of triglyceride-rich lipoproteins

    Pla2g12b drives expansion of triglyceride-rich lipoproteins by James H. Thierer, Ombretta Foresti, Pradeep Kumar Yadav, Meredith H. Wilson, Tabea O. C. Moll, Meng-Chieh Shen, Elisabeth M. Busch-Nentwich, Margaret Morash, Karen L. Mohlke, John F. Rawls, Vivek Malhotra, M. Mahmood Hussain, Steven A. Farber

    Published 2024-03-01
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  12. 12
    Publisher Correction: Pla2g12b drives expansion of triglyceride-rich lipoproteins

    Publisher Correction: Pla2g12b drives expansion of triglyceride-rich lipoproteins by James H. Thierer, Ombretta Foresti, Pradeep Kumar Yadav, Meredith H. Wilson, Tabea O. C. Moll, Meng-Chieh Shen, Elisabeth M. Busch-Nentwich, Margaret Morash, Karen L. Mohlke, John F. Rawls, Vivek Malhotra, M. Mahmood Hussain, Steven A. Farber

    Published 2024-03-01
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  13. 13
    The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance.

    The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance. by Zong Miao, Marcus Alvarez, Arthur Ko, Yash Bhagat, Elior Rahmani, Brandon Jew, Sini Heinonen, Linda Liliana Muñoz-Hernandez, Miguel Herrera-Hernandez, Carlos Aguilar-Salinas, Teresa Tusie-Luna, Karen L Mohlke, Markku Laakso, Kirsi H Pietiläinen, Eran Halperin, Päivi Pajukanta

    Published 2020-09-01
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  14. 14
    Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus

    Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus by Maren E. Cannon, Qing Duan, Ying Wu, Monica Zeynalzadeh, Zheng Xu, Antti J. Kangas, Pasi Soininen, Mika Ala-Korpela, Mete Civelek, Aldons J. Lusis, Johanna Kuusisto, Francis S. Collins, Michael Boehnke, Hua Tang, Markku Laakso, Yun Li, Karen L. Mohlke

    Published 2017-09-01
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  15. 15
    Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

    Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS by David Z. Pan, Kristina M. Garske, Marcus Alvarez, Yash V. Bhagat, James Boocock, Elina Nikkola, Zong Miao, Chelsea K. Raulerson, Rita M. Cantor, Mete Civelek, Craig A. Glastonbury, Kerrin S. Small, Michael Boehnke, Aldons J. Lusis, Janet S. Sinsheimer, Karen L. Mohlke, Markku Laakso, Päivi Pajukanta, Arthur Ko

    Published 2018-04-01
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  16. 16
    Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

    Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS by David Z. Pan, Kristina M. Garske, Marcus Alvarez, Yash V. Bhagat, James Boocock, Elina Nikkola, Zong Miao, Chelsea K. Raulerson, Rita M. Cantor, Mete Civelek, Craig A. Glastonbury, Kerrin S. Small, Michael Boehnke, Aldons J. Lusis, Janet S. Sinsheimer, Karen L. Mohlke, Markku Laakso, Päivi Pajukanta, Arthur Ko

    Published 2018-08-01
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  17. 17
    Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

    Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. by James P Davis, Jeroen R Huyghe, Adam E Locke, Anne U Jackson, Xueling Sim, Heather M Stringham, Tanya M Teslovich, Ryan P Welch, Christian Fuchsberger, Narisu Narisu, Peter S Chines, Antti J Kangas, Pasi Soininen, Mika Ala-Korpela, Johanna Kuusisto, Francis S Collins, Markku Laakso, Michael Boehnke, Karen L Mohlke

    Published 2017-10-01
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  18. 18
    Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey.

    Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey. by Cassandra N Spracklen, Jinxiu Shi, Swarooparani Vadlamudi, Ying Wu, Meng Zou, Chelsea K Raulerson, James P Davis, Monica Zeynalzadeh, Kayla Jackson, Wentao Yuan, Haifeng Wang, Weihua Shou, Ying Wang, Jingchun Luo, Leslie A Lange, Ethan M Lange, Barry M Popkin, Penny Gordon-Larsen, Shufa Du, Wei Huang, Karen L Mohlke

    Published 2018-04-01
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  19. 19
    Correction to: Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes

    Correction to: Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes by David Z. Pan, Zong Miao, Caroline Comenho, Sandhya Rajkumar, Amogha Koka, Seung Hyuk T. Lee, Marcus Alvarez, Dorota Kaminska, Arthur Ko, Janet S. Sinsheimer, Karen L. Mohlke, Nicholas Mancuso, Linda Liliana Muñoz-Hernandez, Miguel Herrera-Hernandez, Maria Teresa Tusié-Luna, Carlos Aguilar-Salinas, Kirsi H. Pietiläinen, Jussi Pihlajamäki, Markku Laakso, Kristina M. Garske, Päivi Pajukanta

    Published 2021-08-01
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  20. 20
    Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes

    Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes by David Z. Pan, Zong Miao, Caroline Comenho, Sandhya Rajkumar, Amogha Koka, Seung Hyuk T. Lee, Marcus Alvarez, Dorota Kaminska, Arthur Ko, Janet S. Sinsheimer, Karen L. Mohlke, Nicholas Mancuso, Linda Liliana Muñoz-Hernandez, Miguel Herrera-Hernandez, Maria Teresa Tusié-Luna, Carlos Aguilar-Salinas, Kirsi H. Pietiläinen, Jussi Pihlajamäki, Markku Laakso, Kristina M. Garske, Päivi Pajukanta

    Published 2021-08-01
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