Immune regulation of metastasis: mechanistic insights and therapeutic opportunities by Olga S. Blomberg, Lorenzo Spagnuolo, Karin E. de Visser

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Early Neoplastic Progression Is Complement Independent by Karin E. de Visser, Lidiya V. Korets, Lisa M. Coussens

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Exploiting the immunomodulatory properties of chemotherapeutic drugs to improve the success of cancer immunotherapy by Kelly eKersten, Camilla eSalvagno, Karin E de Visser

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hMRP8-ATTAC Mice: A New Model for Conditional and Reversible Neutrophil Ablation by Danique E. M. Duits, Camilla Salvagno, Elisabeth A. M. Raeven, Kim Vrijland, Marjolein C. Stip, Cheei-Sing Hau, Daphne Kaldenbach, Karin E. de Visser

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Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients by Sander Tuit, Camilla Salvagno, Theodore S. Kapellos, Cheei-Sing Hau, Lea Seep, Marie Oestreich, Kathrin Klee, Karin E. de Visser, Thomas Ulas, Joachim L. Schultze

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Transformed Canine and Murine Mesenchymal Stem Cells as a Model for Sarcoma with Complex Genomics by Natasja Franceschini, Bas Verbruggen, Marianna A. Tryfonidou, Alwine B. Kruisselbrink, Hans Baelde, Karin E. de Visser, Karoly Szuhai, Anne-Marie Cleton-Jansen, Judith V. M. G. Bovée

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Pro-mutagenic effects of the gut microbiota in a Lynch syndrome mouse model by Wietske Pieters, Floor Hugenholtz, Kevin Kos, Maxime Cammeraat, Teddy C. Moliej, Daphne Kaldenbach, Sjoerd Klarenbeek, Mark Davids, Lisa Drost, Charlotte de Konink, Elly Delzenne-Goette, Karin E. de Visser, Hein te Riele

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Tumor-associated macrophages promote intratumoral conversion of conventional CD4+ T cells into regulatory T cells via PD-1 signalling by Kevin Kos, Camilla Salvagno, Max D. Wellenstein, Muhammad A. Aslam, Denize A. Meijer, Cheei-Sing Hau, Kim Vrijland, Daphne Kaldenbach, Elisabeth A.M. Raeven, Martina Schmittnaegel, Carola H. Ries, Karin E. de Visser

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Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages by Kelly Kersten, Seth B. Coffelt, Marlous Hoogstraat, Niels J.M. Verstegen, Kim Vrijland, Metamia Ciampricotti, Chris W. Doornebal, Cheei-Sing Hau, Max D. Wellenstein, Camilla Salvagno, Parul Doshi, Esther H. Lips, Lodewyk F.A. Wessels, Karin E. de Visser

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Neoadjuvant immune checkpoint blockade triggers persistent and systemic Treg activation which blunts therapeutic efficacy against metastatic spread of breast tumors by Olga S. Blomberg, Kevin Kos, Lorenzo Spagnuolo, Olga I. Isaeva, Hannah Garner, Max D. Wellenstein, Noor Bakker, Danique E.M. Duits, Kelly Kersten, Sjoerd Klarenbeek, Cheei-Sing Hau, Daphne Kaldenbach, Elisabeth A.M. Raeven, Kim Vrijland, Marleen Kok, Karin E. de Visser

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Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system by Sjoerd Klarenbeek, Chris W. Doornebal, Sjors M. Kas, Nicola Bonzanni, Jinhyuk Bhin, Tanya M. Braumuller, Ingrid van der Heijden, Mark Opdam, Philip C. Schouten, Kelly Kersten, Roebi de Bruijn, Daniel Zingg, Julia Yemelyanenko, Lodewyk F.A. Wessels, Karin E. de Visser, Jos Jonkers

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Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival by Marcelo Sobral-Leite, Koen Van de Vijver, Magali Michaut, Rianne van der Linden, Gerrit K.J. Hooijer, Hugo M. Horlings, Tesa M. Severson, Anna Marie Mulligan, Nayana Weerasooriya, Joyce Sanders, Annuska M Glas, Diederik Wehkamp, Lorenza Mittempergher, Kelly Kersten, Ashley Cimino-Mathews, Dennis Peters, Erik Hooijberg, Annegien Broeks, Marc J. van de Vijver, Rene Bernards, Irene L. Andrulis, Marleen Kok, Karin E. de Visser, Marjanka K. Schmidt

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MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling by Dario Zimmerli, Chiara S. Brambillasca, Francien Talens, Jinhyuk Bhin, Renske Linstra, Lou Romanens, Arkajyoti Bhattacharya, Stacey E. P. Joosten, Ana Moises Da Silva, Nuno Padrao, Max D. Wellenstein, Kelly Kersten, Mart de Boo, Maurits Roorda, Linda Henneman, Roebi de Bruijn, Stefano Annunziato, Eline van der Burg, Anne Paulien Drenth, Catrin Lutz, Theresa Endres, Marieke van de Ven, Martin Eilers, Lodewyk Wessels, Karin E. de Visser, Wilbert Zwart, Rudolf S. N. Fehrmann, Marcel A. T. M. van Vugt, Jos Jonkers

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