Acute cholecystitis in high risk surgical patients: percutaneous cholecystostomy versus laparoscopic cholecystectomy (CHOCOLATE trial): Study protocol for a randomized controlled t... by Kortram Kirsten, van Ramshorst Bert, Bollen Thomas L, Besselink Marc GH, Gouma Dirk J, Karsten Tom, Kruyt Philip M, Nieuwenhuijzen Grard AP, Kelder Johannes C, Tromp Ellen, Boerma Djamila

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DIRECT trial. Diverticulitis recurrences or continuing symptoms: Operative versus conservative Treatment. <it>A MULTICENTER RANDOMISED CLINICAL TRIAL</it> by van de Wall Bryan JM, Draaisma Werner A, Consten Esther CJ, van der Graaf Yolanda, Otten Marten H, de Wit G, van Stel Henk F, Gerhards Michael F, Wiezer Marinus J, Cense Huib A, Stockmann Hein BAC, Leijtens Jeroen WA, Zimmerman David DE, Belgers Eric, van Wagensveld Bart A, Sonneveld Eric DJA, Prins Hubert A, Coene Peter PLO, Karsten Tom M, Klaase Joost M, Statius Muller Markwin G, Crolla Rogier MPH, Broeders Ivo AMJ

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Minimally invasive 'step-up approach' versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTER trial): design and rationale of a randomised controlled mu... by Houdijk Lex PJ, Hesselink Eric J, van der Harst Erwin, Gouma Dirk J, Consten Esther CJ, Cuesta Miguel A, Schaapherder Alexander FM, van Ramshorst Bert, Ploeg Rutger J, van Leeuwen Maarten S, Lameris Johan S, Hofker Sijbrand S, van Goor Harry, van Eijck Casper HJ, Dejong Cornelis HC, Buskens Erik, Bollen Thomas L, Boermeester Marja A, Nieuwenhuijs Vincent B, van Santvoort Hjalmar C, Besselink Marc GH, Karsten Tom M, van Laarhoven Cees JHM, Pierie Jean-Pierre EN, Rosman Camiel, Bilgen Ernst, Timmer Robin, van der Tweel Ingeborg, de Wit Ralph J, Witteman Ben JM, Gooszen Hein G

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