Nucleic acid-based vaccines targeting respiratory syncytial virus: Delivering the goods by Trevor R. F. Smith, Katherine Schultheis, Kate E. Broderick

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Optimized In Vivo Transfer of Small Interfering RNA Targeting Dermal Tissue Using In Vivo Surface Electroporation by Kate E Broderick, Amy Chan, Feng Lin, Xuefei Shen, Gleb Kichaev, Amir S Khan, Justin Aubin, Tracy S Zimmermann, Niranjan Y. Sardesai

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Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ by Kaustuv Banerjee, Julie Hickman, Andrew Geall, Jeffrey B. Ulmer, Gleb Kichaev, Niranjan Y. Sardesai, Yen Cu, Susan Barnett, Gillis Otten, Kate E. Broderick

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Immunogenicity of a protective intradermal DNA vaccine against lassa virus in cynomolgus macaques by Jingjing Jiang, Preeti Banglore, Kathleen A. Cashman, Connie S. Schmaljohn, Katherine Schultheis, Holly Pugh, Jacklyn Nguyen, Laurent M. Humeau, Kate E. Broderick, Stephanie J. Ramos

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Elucidating the Kinetics of Expression and Immune Cell Infiltration Resulting from Plasmid Gene Delivery Enhanced by Surface Dermal Electroporation by Kate E. Broderick, Niranjan Y. Sardesai, Trevor R. F. Smith, William B. Kiosses, Christine L. Knott, Gleb Kichaev, Dinah H. Amante, Janess M. Mendoza

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DNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs by Kathleen A. Cashman, Eric R. Wilkinson, Suzanne E. Wollen, Joshua D. Shamblin, Justine M. Zelko, Jeremy J. Bearss, Xiankun Zeng, Kate E. Broderick, Connie S. Schmaljohn

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Gag and env conserved element CE DNA vaccines elicit broad cytotoxic T cell responses targeting subdominant epitopes of HIV and SIV Able to recognize virus-infected cells in macaqu... by Xintao Hu, Zhongyan Lu, Antonio Valentin, Margherita Rosati, Kate E. Broderick, Niranjan Y. Sardesai, Preston A. Marx, James I. Mullins, George N. Pavlakis, Barbara K. Felber

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DNA vaccination strategy targets epidermal dendritic cells, initiating their migration and induction of a host immune response by Trevor RF Smith, Katherine Schultheis, William B Kiosses, Dinah H Amante, Janess M Mendoza, John C Stone, Jay R McCoy, Niranjan Y Sardesai, Kate E Broderick

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Adjuvant Screen Identifies Synthetic DNA-Encoding Flt3L and CD80 Immunotherapeutics as Candidates for Enhancing Anti-tumor T Cell Responses by Amy Haseley Thorne, Kirsten N. Malo, Ashley J. Wong, Tricia T. Nguyen, Neil Cooch, Charles Reed, Jian Yan, Kate E. Broderick, Trevor R. F. Smith, Emma L. Masteller, Laurent Humeau

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Immunotherapy with DNA vaccine and live attenuated rubella/SIV gag vectors plus early ART can prevent SIVmac251 viral rebound in acutely infected rhesus macaques. by Konstantin Virnik, Margherita Rosati, Alexei Medvedev, Aaron Scanlan, Gabrielle Walsh, Frances Dayton, Kate E Broderick, Mark Lewis, Yvonne Bryson, Jeffrey D Lifson, Ruth M Ruprecht, Barbara K Felber, Ira Berkower

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HIV Env conserved element DNA vaccine alters immunodominance in macaques by Xintao Hu, Antonio Valentin, Margherita Rosati, Siriphan Manocheewa, Candido Alicea, Bhabadeb Chowdhury, Jenifer Bear, Kate E. Broderick, Niranjan Y. Sardesai, Sylvie Le Gall, James I. Mullins, George N. Pavlakis, Barbara K. Felber

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Enhanced Efficacy of a Codon-Optimized DNA Vaccine Encoding the Glycoprotein Precursor Gene of Lassa Virus in a Guinea Pig Disease Model When Delivered by Dermal Electroporation by Niranjan Y. Sardesai, Connie S. Schmaljohn, Catherine V. Badger, Mary C. Guttieri, Kristin W. Spik, Carl I. Shaia, Amy C. Shurtleff, Todd M. Bell, Kate E. Broderick, Eric R. Wilkinson, Kathleen A. Cashman

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A DNA vaccine delivered by dermal electroporation fully protects cynomolgus macaques against Lassa fever by Kathleen A. Cashman, Eric R. Wilkinson, Carl I. Shaia, Paul R. Facemire, Todd M. Bell, Jeremy J. Bearss, Joshua D. Shamblin, Suzanne E. Wollen, Kate E. Broderick, Niranjan Y. Sardesai, Connie S. Schmaljohn

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Live Virus Neutralisation of the 501Y.V1 and 501Y.V2 SARS-CoV-2 Variants following INO-4800 Vaccination of Ferrets by Shane Riddell, Sarah Goldie, Alexander J. McAuley, Michael J. Kuiper, Peter A. Durr, Kim R. Blasdell, Mary Tachedjian, Julian D. Druce, Trevor R. F. Smith, Kate E. Broderick, Seshadri S. Vasan, Seshadri S. Vasan

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Active immunoprophylaxis with a synthetic DNA-encoded monoclonal anti-respiratory syncytial virus scFv-Fc fusion protein confers protection against infection and durable activity by Katherine Schultheis, Holly M Pugh, Janet Oh, Jacklyn Nguyen, Bryan Yung, Charles Reed, Neil Cooch, Jing Chen, Jian Yan, Kar Muthumani, Laurent M. Humeau, David B. Weiner, Kate E. Broderick, Trevor R. F. Smith

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Protection against Borreliella burgdorferi infection mediated by a synthetically engineered DNA vaccine by Ghiabe H. Guibinga, Bikash Sahay, Heather Brown, Neil Cooch, Jing Chen, Jian Yan, Charles Reed, Meerambika Mishra, Bryan Yung, Holly Pugh, Katherine Schultheis, Rianne N. Esquivel, David B. Weiner, Laurent H. Humeau, Kate E. Broderick, Trevor R.F. Smith

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Multivalent DNA Vaccines as a Strategy to Combat Multiple Concurrent Epidemics: Mosquito-Borne and Hemorrhagic Fever Viruses by Jingjing Jiang, Stephanie J. Ramos, Preeti Bangalore, Dustin Elwood, Kathleen A. Cashman, Sagar B. Kudchodkar, Katherine Schultheis, Holly Pugh, Jewell Walters, Jared Tur, Jian Yan, Ami Patel, Kar Muthumani, Connie S. Schmaljohn, David B. Weiner, Laurent M. Humeau, Kate E. Broderick

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Synthetic nucleic acid antibody prophylaxis confers rapid and durable protective immunity against Zika virus challenge by Hyeree Choi, Sagar B. Kudchodkar, Emma L. Reuschel, Kanika Asija, Piyush Borole, Sangya Agarwal, Lucas Van Gorder, Charles C. Reed, Gayathri Gulendran, Stephanie Ramos, Kate E. Broderick, J Joseph Kim, Kenneth E. Ugen, Gary Kobinger, Don L. Siegel, David B. Weiner, Kar Muthumani

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HIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice. by Viraj Kulkarni, Margherita Rosati, Antonio Valentin, Brunda Ganneru, Ashish K Singh, Jian Yan, Morgane Rolland, Candido Alicea, Rachel Kelly Beach, Gen-Mu Zhang, Sylvie Le Gall, Kate E Broderick, Niranjan Y Sardesai, David Heckerman, Beatriz Mothe, Christian Brander, David B Weiner, James I Mullins, George N Pavlakis, Barbara K Felber

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DMAb inoculation of synthetic cross reactive antibodies protects against lethal influenza A and B infections by Sarah T. C. Elliott, Nicole L. Kallewaard, Ebony Benjamin, Leslie Wachter-Rosati, Josephine M. McAuliffe, Ami Patel, Trevor R. F. Smith, Katherine Schultheis, Daniel H. Park, Seleeke Flingai, Megan C. Wise, Janess Mendoza, Stephanie Ramos, Kate E. Broderick, Jian Yan, Laurent M. Humeau, Niranjan Y. Sardesai, Kar Muthumani, Qing Zhu, David B. Weiner

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