mRNA-1273 vaccination protects against SARS-CoV-2–elicited lung inflammation in nonhuman primates od Adam T. Waickman, Kaitlin Victor, Krista Newell, Tao Li, Heather Friberg, Kathryn E. Foulds, Mario Roederer, Diane L. Bolton, Jeffrey R. Currier, Robert Seder

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Ebola-GP DNA Prime rAd5-GP Boost: Influence of Prime Frequency and Prime/Boost Time Interval on the Immune Response in Non-human Primates od Hadar Marcus, Emily Thompson, Yan Zhou, Michael Bailey, Mitzi M. Donaldson, Daphne A. Stanley, Clement Asiedu, Kathryn E. Foulds, Mario Roederer, Juan I. Moliva, Nancy J. Sullivan

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Myeloid Cell Crosstalk Regulates the Efficacy of the DNA/ALVAC/gp120 HIV Vaccine Candidate od Monica Vaccari, Slim Fourati, Dallas R. Brown, Isabela Silva de Castro, Massimiliano Bissa, Luca Schifanella, Melvin N. Doster, Kathryn E. Foulds, Mario Roederer, Richard A. Koup, Yongjun Sui, Jay A. Berzofsky, Rafick-Pierre Sekaly, Genoveffa Franchini

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Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans od Kalani Ratnasiri, Hong Zheng, Jiaying Toh, Zhiyuan Yao, Veronica Duran, Michele Donato, Mario Roederer, Megha Kamath, John-Paul M. Todd, Matthew Gagne, Kathryn E. Foulds, Joseph R. Francica, Kizzmekia S. Corbett, Daniel C. Douek, Robert A. Seder, Shirit Einav, Catherine A. Blish, Purvesh Khatri

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Interaction dynamics between innate and adaptive immune cells responding to SARS-CoV-2 vaccination in non-human primates od Chaim A. Schramm, Damee Moon, Lowrey Peyton, Noemia S. Lima, Christian Wake, Kristin L. Boswell, Amy R. Henry, Farida Laboune, David Ambrozak, Samuel W. Darko, I-Ting Teng, Kathryn E. Foulds, Andrea Carfi, Darin K. Edwards, Peter D. Kwong, Richard A. Koup, Robert A. Seder, Daniel C. Douek

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Investigation of the impact of clonal hematopoiesis on severity and pathophysiology of COVID-19 in rhesus macaques od Tae-Hoon Shin, Tae-Hoon Shin, Yifan Zhou, Yifan Zhou, Yifan Zhou, Byung-Chul Lee, So Gun Hong, Shayne F. Andrew, Barbara J. Flynn, Matthew Gagne, John-Paul M. Todd, Ian N. Moore, Anthony Cook, Mark G. Lewis, Kathryn E. Foulds, Robert A. Seder, Daniel C. Douek, Mario Roederer, Cynthia E. Dunbar

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Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes. od Sean P O'Brien, Adrienne E Swanstrom, Amarendra Pegu, Sung-Youl Ko, Taina T Immonen, Gregory Q Del Prete, Christine M Fennessey, Jason Gorman, Kathryn E Foulds, Stephen D Schmidt, Nicole Doria-Rose, Carolyn Williamson, Theodora Hatziioannou, Paul D Bieniasz, Hui Li, George M Shaw, John R Mascola, Richard A Koup, Peter D Kwong, Jeffrey D Lifson, Mario Roederer, Brandon F Keele

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Frequency-potency analysis of IgG+ memory B cells delineates neutralizing antibody responses at single-cell resolution od Michelle K. Tenggara, Seo-Ho Oh, Catherine Yang, Hardik K. Nariya, Amanda M. Metz, Amit A. Upadhyay, Dedeepya R. Gudipati, Lizheng Guo, Emily G. McGhee, Kiran Gill, Elise G. Viox, Rosemarie D. Mason, Nicole A. Doria-Rose, Kathryn E. Foulds, John R. Mascola, Yuhong Du, Haian Fu, John D. Altman, Qi Yan, Zizhang Sheng, Steven E. Bosinger, Rui Kong

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Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques. od Gerard Zurawski, Sandra Zurawski, Anne-Laure Flamar, Laura Richert, Ralf Wagner, Georgia D Tomaras, David C Montefiori, Mario Roederer, Guido Ferrari, Christine Lacabaratz, Henri Bonnabau, Peter Klucar, Zhiqing Wang, Kathryn E Foulds, Shing-Fen Kao, Nicole L Yates, Celia LaBranche, Bertram L Jacobs, Karen Kibler, Benedikt Asbach, Alexander Kliche, Andres Salazar, Steve Reed, Steve Self, Raphael Gottardo, Lindsey Galmin, Deborah Weiss, Anthony Cristillo, Rodolphe Thiebaut, Giuseppe Pantaleo, Yves Levy

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Early and Long-Term HIV-1 Immunogenicity Induced in Macaques by the Combined Administration of DNA, NYVAC and Env Protein-Based Vaccine Candidates: The AUP512 Study od Beatriz Perdiguero, Beatriz Perdiguero, Benedikt Asbach, Carmen E. Gómez, Carmen E. Gómez, Josef Köstler, Josef Köstler, Susan W. Barnett, Marguerite Koutsoukos, Deborah E. Weiss, Anthony D. Cristillo, Kathryn E. Foulds, Mario Roederer, David C. Montefiori, Nicole L. Yates, Guido Ferrari, Xiaoying Shen, Sheetal Sawant, Georgia D. Tomaras, Alicia Sato, William J. Fulp, Raphael Gottardo, Raphael Gottardo, Raphael Gottardo, Song Ding, Jonathan L. Heeney, Giuseppe Pantaleo, Mariano Esteban, Mariano Esteban, Ralf Wagner, Ralf Wagner

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Variant-proof high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways od Matthew Gagne, Barbara J. Flynn, Christopher Cole Honeycutt, Dillon R. Flebbe, Shayne F. Andrew, Samantha J. Provost, Lauren McCormick, Alex Van Ry, Elizabeth McCarthy, John-Paul M. Todd, Saran Bao, I-Ting Teng, Shir Marciano, Yinon Rudich, Chunlin Li, Shilpi Jain, Bushra Wali, Laurent Pessaint, Alan Dodson, Anthony Cook, Mark G. Lewis, Hanne Andersen, Jiří Zahradník, Mehul S. Suthar, Martha C. Nason, Kathryn E. Foulds, Peter D. Kwong, Mario Roederer, Gideon Schreiber, Robert A. Seder, Daniel C. Douek

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Fusion peptide priming reduces immune responses to HIV-1 envelope trimer base od Angela R. Corrigan, Hongying Duan, Cheng Cheng, Christopher A. Gonelli, Li Ou, Kai Xu, Megan E. DeMouth, Hui Geng, Sandeep Narpala, Sarah O’Connell, Baoshan Zhang, Tongqing Zhou, Manjula Basappa, Jeffrey C. Boyington, Steven J. Chen, Sijy O’Dell, Amarendra Pegu, Tyler Stephens, Yaroslav Tsybovsky, Jelle van Schooten, John P. Todd, Shuishu Wang, Nicole A. Doria-Rose, Kathryn E. Foulds, Richard A. Koup, Adrian B. McDermott, Marit J. van Gils, Peter D. Kwong, John R. Mascola

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Long trimer-immunization interval and appropriate adjuvant reduce immune responses to the soluble HIV-1-envelope trimer base od Hongying Duan, Angela R. Corrigan, Cheng Cheng, Andrea Biju, Christopher A. Gonelli, Adam S. Olia, I-Ting Teng, Kai Xu, Sijy O’Dell, Sandeep Narpala, Mike Castro, Leonid Serebryannyy, Jennifer Wang, Danealle K. Parchment, Edward K. Sarfo, Jelle van Schooten, John-Paul Todd, Shuishu Wang, Darcy R. Harris, Hui Geng, Alexander J. Jafari, Ruth A. Woodward, Nicole A. Doria-Rose, Kathryn E. Foulds, Adrian B. McDermott, Marit J. van Gils, Richard A. Koup, Theodore C. Pierson, Peter D. Kwong, John R. Mascola

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Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation od Tongqing Zhou, Nicole A. Doria-Rose, Cheng Cheng, Guillaume B.E. Stewart-Jones, Gwo-Yu Chuang, Michael Chambers, Aliaksandr Druz, Hui Geng, Krisha McKee, Young Do Kwon, Sijy O’Dell, Mallika Sastry, Stephen D. Schmidt, Kai Xu, Lei Chen, Rita E. Chen, Mark K. Louder, Marie Pancera, Timothy G. Wanninger, Baoshan Zhang, Anqi Zheng, S. Katie Farney, Kathryn E. Foulds, Ivelin S. Georgiev, M. Gordon Joyce, Thomas Lemmin, Sandeep Narpala, Reda Rawi, Cinque Soto, John-Paul Todd, Chen-Hsiang Shen, Yaroslav Tsybovsky, Yongping Yang, Peng Zhao, Barton F. Haynes, Leonidas Stamatatos, Michael Tiemeyer, Lance Wells, Diana G. Scorpio, Lawrence Shapiro, Adrian B. McDermott, John R. Mascola, Peter D. Kwong

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