Kelly Chibale

Kelly Chibale PhD, MASSAf, FAAS, Fellow of UCT, FRSSAf, FRSC (born 1964) is professor of organic chemistry at the University of Cape Town, and the founder and director of [http://www.h3d.uct.ac.za/ H3D research center] and [https://h3dfoundation.org H3D Foundation NPC]. In 2018 he was recognised as one of Fortune magazine's top 50 World's Greatest Leaders. His research focuses on drug discovery and the development of tools and models to contribute to improving treatment outcomes in people of African descent or heritage. Provided by Wikipedia
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  1. 1
    Towards broadspectrum antiprotozoal agents

    Towards broadspectrum antiprotozoal agents by Kelly Chibale

    Published 2003-01-01
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  2. 2
    Cell-Based Medicinal Chemistry Optimization of High Throughput Screening Hits towards Orally Active Antimalarial and Antituberculosis Agents

    Cell-Based Medicinal Chemistry Optimization of High Throughput Screening Hits towards Orally Active Antimalarial and Antituberculosis Agents by Kelly Chibale

    Published 2017-12-01
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  3. 3
    Novel tetracyclic structures from the synthesis of thiolactone-isatin hybrids

    Novel tetracyclic structures from the synthesis of thiolactone-isatin hybrids by Renate Hazel Hans, Hong Su, Kelly Chibale

    Published 2010-07-01
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  4. 4
    Synthesis and In Vitro Antiprotozoan Evaluation of 4-/8-Aminoquinoline-based Lactams and Tetrazoles

    Synthesis and In Vitro Antiprotozoan Evaluation of 4-/8-Aminoquinoline-based Lactams and Tetrazoles by Matshawandile Tukulula, Stefan Louw, Mathew Njoroge, Kelly Chibale

    Published 2020-12-01
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  5. 5
    The Role of Natural Products in Drug Discovery and Development against Neglected Tropical Diseases

    The Role of Natural Products in Drug Discovery and Development against Neglected Tropical Diseases by Peter Mubanga Cheuka, Godfrey Mayoka, Peggoty Mutai, Kelly Chibale

    Published 2016-12-01
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  6. 6
    Inhibition of trypanothione reductase and glutathione reductase by ferrocenic 4-aminoquinoline ureas

    Inhibition of trypanothione reductase and glutathione reductase by ferrocenic 4-aminoquinoline ureas by Margaret A.L. Blackie, Ahilan Saravanamuthu, Alan H. Fairlamb, Kelly Chibale

    Published 2008-03-01
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  7. 7
    The diaryl-imidazopyridazine anti-plasmodial compound, MMV652103, exhibits anti-breast cancer activity

    The diaryl-imidazopyridazine anti-plasmodial compound, MMV652103, exhibits anti-breast cancer activity by Alexis Neumann-Mufweba, Serah Kimani, Saif Feroz Khan, Kelly Chibale, Sharon Prince

    Published 2022-04-01
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  8. 8
    First fully-automated AI/ML virtual screening cascade implemented at a drug discovery centre in Africa

    First fully-automated AI/ML virtual screening cascade implemented at a drug discovery centre in Africa by Gemma Turon, Jason Hlozek, John G. Woodland, Ankur Kumar, Kelly Chibale, Miquel Duran-Frigola

    Published 2023-09-01
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  9. 9
    Synthesis of 2-amino-3-arylpropan-1-ols and 1-(2,3-diaminopropyl)-1,2,3-triazoles and evaluation of their antimalarial activity

    Synthesis of 2-amino-3-arylpropan-1-ols and 1-(2,3-diaminopropyl)-1,2,3-triazoles and evaluation of their antimalarial activity by Matthias D’hooghe, Stéphanie Vandekerckhove, Karen Mollet, Karel Vervisch, Stijn Dekeukeleire, Liesbeth Lehoucq, Carmen Lategan, Peter J. Smith, Kelly Chibale, Norbert De Kimpe

    Published 2011-12-01
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  10. 10
    Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed <i>ortho</i>-C(sp<sup>2</sup>)-H-Hydroxylation

    Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed <i>ortho</i>-C(sp<sup>2</sup>)-H-Hydroxylation by Alexander Berger, Talea Knak, Anna-Lene Kiffe-Delf, Korana Mudrovcic, Vinayak Singh, Mathew Njoroge, Bjoern B. Burckhardt, Mohanraj Gopalswamy, Beate Lungerich, Lutz Ackermann, Holger Gohlke, Kelly Chibale, Rainer Kalscheuer, Thomas Kurz

    Published 2022-08-01
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  11. 11
    Lerisetron Analogues with Antimalarial Properties: Synthesis, Structure–Activity Relationship Studies, and Biological Assessment

    Lerisetron Analogues with Antimalarial Properties: Synthesis, Structure–Activity Relationship Studies, and Biological Assessment by Rudolf Mueller, Virsinha Reddy, Aloysius T. Nchinda, Fanuel Mebrahtu, Dale Taylor, Nina Lawrence, Lloyd Tanner, Marine Barnabe, Charles J. Eyermann, Bin Zou, Ravinder R. Kondreddi, Suresh B. Lakshminarayana, Matthias Rottmann, Leslie J. Street, Kelly Chibale

    Published 2020-03-01
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  12. 12
    Drug discovery research in Ghana, challenges, current efforts, and the way forward

    Drug discovery research in Ghana, challenges, current efforts, and the way forward by Richard Kwamla Amewu, Patrick Amoateng, Patrick Kobina Arthur, Prince Asare, Isaac Asiamah, Daniel Boamah, Isaac Darko Otchere, Cedric Dzidzor Amengor, Edmund Ekuadzi, Kelly Chibale, Susan Jane Farrell, Regina Appiah-Oppong, Dorcas Osei-Safo, Kevin David Read, Ian Hugh Gilbert, Dorothy Yeboah-Manu

    Published 2022-09-01
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  13. 13
    Drug discovery research in Ghana, challenges, current efforts, and the way forward.

    Drug discovery research in Ghana, challenges, current efforts, and the way forward. by Richard Kwamla Amewu, Patrick Amoateng, Patrick Kobina Arthur, Prince Asare, Isaac Asiamah, Daniel Boamah, Isaac Darko Otchere, Cedric Dzidzor Amengor, Edmund Ekuadzi, Kelly Chibale, Susan Jane Farrell, Regina Appiah-Oppong, Dorcas Osei-Safo, Kevin David Read, Ian Hugh Gilbert, Dorothy Yeboah-Manu

    Published 2022-09-01
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  14. 14
    Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB.

    Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB. by Ruslana Bryk, Shashirekha Mundhra, Xiuju Jiang, Madeleine Wood, Daniel Pfau, Elaina Weber, Suna Park, Li Zhang, Colin Wilson, Renier Van der Westhuyzen, Leslie Street, Kelly Chibale, Matthew Zimmerman, Véronique Dartois, Nunzia Pastore, Andrea Ballabio, Natalie Hawryluk, Stacie Canan, Vikram Khetani, Joseph Camardo, Carl Nathan

    Published 2020-06-01
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  15. 15
    Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box

    Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box by Janette Reader, Mariëtte E. van der Watt, Dale Taylor, Claire Le Manach, Nimisha Mittal, Sabine Ottilie, Anjo Theron, Phanankosi Moyo, Erica Erlank, Luisa Nardini, Nelius Venter, Sonja Lauterbach, Belinda Bezuidenhout, Andre Horatscheck, Ashleigh van Heerden, Natalie J. Spillman, Anne N. Cowell, Jessica Connacher, Daniel Opperman, Lindsey M. Orchard, Manuel Llinás, Eva S. Istvan, Daniel E. Goldberg, Grant A. Boyle, David Calvo, Dalu Mancama, Theresa L. Coetzer, Elizabeth A. Winzeler, James Duffy, Lizette L. Koekemoer, Gregory Basarab, Kelly Chibale, Lyn-Marié Birkholtz

    Published 2021-01-01
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