An update on the genetics of colorectal cancer. by Kemp, Z, Thirlwell, C, Sieber, O, Silver, A, Tomlinson, I

CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability. by Kemp, Z, Rowan, A, Chambers, W, Wortham, N, Halford, S, Sieber, O, Mortensen, N, von Herbay, A, Gunther, T, Ilyas, M, Tomlinson, I

Refining molecular analysis in the pathways of colorectal carcinogenesis. by Rowan, A, Halford, S, Gaasenbeek, M, Kemp, Z, Sieber, O, Volikos, E, Douglas, E, Fiegler, H, Carter, N, Talbot, I, Silver, A, Tomlinson, I

Implementing rapid, robust, cost-effective, patient-centred, routine genetic testing in ovarian cancer patients by George, A, Riddell, D, Seal, S, Talukdar, S, Mahamdallie, S, Ruark, E, Cloke, V, Slade, I, Kemp, Z, Gore, M, Strydom, A, Banerjee, S, Hanson, H, Rahman, N

Evidence of linkage to chromosome 9q22.33 in colorectal cancer kindreds from the United Kingdom. by Kemp, Z, Carvajal-Carmona, L, Barclay, E, Gorman, M, Martin, L, Wood, W, Rowan, A, Donohue, C, Spain, S, Jaeger, E, Evans, D, Maher, E, Bishop, T, Thomas, H, Houlston, R, Tomlinson, I

Evidence for a colorectal cancer susceptibility locus on chromosome 3q21-q24 from a high-density SNP genome-wide linkage scan (vol 15, pg 2903, 2006) by Kemp, Z, Carvajal-Carmona, L, Spain, S, Barclay, E, Gorman, M, Martin, L, Jaeger, E, Brooks, N, Bishop, D, Thomas, H, Tomlinson, I, Papaemmanuil, E, Webb, E, Sellick, G, Wood, W, Evans, G, Lucassen, A, Maher, E, Houlston, R, Identificat, C

Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer. by Pittman, A, Webb, E, Carvajal-Carmona, L, Howarth, K, Bernardo, D, Broderick, P, Spain, S, Walther, A, Price, A, Sullivan, K, Twiss, P, Fielding, S, Rowan, A, Jaeger, E, Vijayakrishnan, J, Chandler, I, Penegar, S, Qureshi, M, Lubbe, S, Domingo, E, Kemp, Z, Barclay, E, Wood, W, Martin, L, Gorman, M

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. by Tomlinson, I, Webb, E, Carvajal-Carmona, L, Broderick, P, Howarth, K, Pittman, A, Spain, S, Lubbe, S, Walther, A, Sullivan, K, Jaeger, E, Fielding, S, Rowan, A, Vijayakrishnan, J, Domingo, E, Chandler, I, Kemp, Z, Qureshi, M, Farrington, S, Tenesa, A, Prendergast, J, Barnetson, R, Penegar, S, Barclay, E, Wood, W

A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. by Tomlinson, I, Webb, E, Carvajal-Carmona, L, Broderick, P, Kemp, Z, Spain, S, Penegar, S, Chandler, I, Gorman, M, Wood, W, Barclay, E, Lubbe, S, Martin, L, Sellick, G, Jaeger, E, Hubner, R, Wild, R, Rowan, A, Fielding, S, Howarth, K, Silver, A, Atkin, W, Muir, K, Logan, R, Kerr, D

A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. by Broderick, P, Carvajal-Carmona, L, Pittman, A, Webb, E, Howarth, K, Rowan, A, Lubbe, S, Spain, S, Sullivan, K, Fielding, S, Jaeger, E, Vijayakrishnan, J, Kemp, Z, Gorman, M, Chandler, I, Papaemmanuil, E, Penegar, S, Wood, W, Sellick, G, Qureshi, M, Teixeira, A, Domingo, E, Barclay, E, Martin, L, Sieber, O

BRCA-DIRECT digital pathway for diagnostic germline genetic testing within a UK breast oncology setting: a randomised, non-inferiority trial by Torr, B, Jones, C, Kavanaugh, G, Hamill, M, Allen, S, Choi, S, Garrett, A, Valganon-Petrizan, M, MacMahon, S, Yuan, L, Way, R, Harder, H, Gold, R, Taylor, A, Gabe, R, Lucassen, A, Manchanda, R, Fallowfield, L, Jenkins, V, Gandhi, A, Evans, DG, George, A, Hubank, M, Kemp, Z

Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. by Jaeger, E, Webb, E, Howarth, K, Carvajal-Carmona, L, Rowan, A, Broderick, P, Walther, A, Spain, S, Pittman, A, Kemp, Z, Sullivan, K, Heinimann, K, Lubbe, S, Domingo, E, Barclay, E, Martin, L, Gorman, M, Chandler, I, Vijayakrishnan, J, Wood, W, Papaemmanuil, E, Penegar, S, Qureshi, M, Farrington, S, Tenesa, A

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. by Tomlinson, I, Webb, E, Carvajal-Carmona, L, Broderick, P, Howarth, K, Pittman, A, Spain, S, Lubbe, S, Walther, A, Sullivan, K, Jaeger, E, Fielding, S, Rowan, A, Vijayakrishnan, J, Domingo, E, Chandler, I, Kemp, Z, Qureshi, M, Farrington, S, Tenesa, A, Prendergast, J, Barnetson, R, Penegar, S, Barclay, E, Wood, W

Deciphering the genetics of hereditary non-syndromic colorectal cancer. by Papaemmanuil, E, Carvajal-Carmona, L, Sellick, G, Kemp, Z, Webb, E, Spain, S, Sullivan, K, Barclay, E, Lubbe, S, Jaeger, E, Vijayakrishnan, J, Broderick, P, Gorman, M, Martin, L, Lucassen, A, Bishop, D, Evans, D, Maher, E, Steinke, V, Rahner, N, Schackert, H, Goecke, T, Holinski-Feder, E, Propping, P, Van Wezel, T

Erratum: Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas (Nature Genetics (2013) 45 (136-144)) by Palles, C, Cazier, J, Howarth, K, Domingo, E, Jones, A, Broderick, P, Kemp, Z, Spain, S, Almeida, E, Salguero, I, Sherborne, A, Chubb, D, Carvajal-Carmona, L, Ma, Y, Kaur, K, Dobbins, S, Barclay, E, Gorman, M, Martin, L, Kovac, M, Humphray, S, Lucassen, A, Holmes, C, Bentley, D, Donnelly, P

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. by Palles, C, Cazier, J, Howarth, K, Domingo, E, Jones, A, Broderick, P, Kemp, Z, Spain, S, Guarino, E, Guarino Almeida, E, Salguero, I, Sherborne, A, Chubb, D, Carvajal-Carmona, L, Ma, Y, Kaur, K, Dobbins, S, Barclay, E, Gorman, M, Martin, L, Kovac, M, Humphray, S, Lucassen, A, Holmes, C, Bentley, D