Biophysical detection of diversity and bias in GPCR function by Werner eJaeger, Stephen eArmstrong, Stephen eHill, Kevin D G Pfleger, Kevin D G Pfleger

Get full text

GPCR heteromers: An overview of their classification, function and physiological relevance by Natasha C. Dale, Natasha C. Dale, Elizabeth K. M. Johnstone, Elizabeth K. M. Johnstone, Elizabeth K. M. Johnstone, Kevin D. G. Pfleger, Kevin D. G. Pfleger, Kevin D. G. Pfleger

Get full text

NanoBRET: The Bright Future of Proximity-Based Assays by Natasha C. Dale, Natasha C. Dale, Natasha C. Dale, Elizabeth K. M. Johnstone, Elizabeth K. M. Johnstone, Elizabeth K. M. Johnstone, Carl W. White, Carl W. White, Carl W. White, Kevin D. G. Pfleger, Kevin D. G. Pfleger, Kevin D. G. Pfleger, Kevin D. G. Pfleger

Get full text

Orexin Signaling: A Complex, Multifaceted Process by Natasha C. Dale, Natasha C. Dale, Natasha C. Dale, Daniel Hoyer, Daniel Hoyer, Daniel Hoyer, Laura H. Jacobson, Laura H. Jacobson, Laura H. Jacobson, Kevin D. G. Pfleger, Kevin D. G. Pfleger, Kevin D. G. Pfleger, Kevin D. G. Pfleger, Elizabeth K. M. Johnstone, Elizabeth K. M. Johnstone, Elizabeth K. M. Johnstone, Elizabeth K. M. Johnstone

Get full text

A nanoluciferase biosensor to investigate endogenous chemokine secretion and receptor binding by Carl W. White, Laura E. Kilpatrick, Kevin D.G. Pfleger, Stephen J. Hill

Get full text

Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpression. by Natália G Sampaio, Martina Kocan, Louis Schofield, Kevin D G Pfleger, Emily M Eriksson

Get full text

Novel Pharmacology Following Heteromerization of the Angiotensin II Type 2 Receptor and the Bradykinin Type 2 Receptor by Elizabeth K. M. Johnstone, Elizabeth K. M. Johnstone, Elizabeth K. M. Johnstone, Mohammed Akli Ayoub, Mohammed Akli Ayoub, Rebecca J. Hertzman, Rebecca J. Hertzman, Heng B. See, Heng B. See, Rekhati S. Abhayawardana, Rekhati S. Abhayawardana, Ruth M. Seeber, Ruth M. Seeber, Kevin D. G. Pfleger, Kevin D. G. Pfleger, Kevin D. G. Pfleger

Get full text

Profiling epidermal growth factor receptor and heregulin receptor 3 heteromerization using receptor tyrosine kinase heteromer investigation technology. by Mohammed Akli Ayoub, Heng B See, Ruth M Seeber, Stephen P Armstrong, Kevin D G Pfleger

Get full text

Characterization of three vasopressin receptor 2 variants: an apparent polymorphism (V266A) and two loss-of-function mutations (R181C and M311V). by Stephen P Armstrong, Ruth M Seeber, Mohammed Akli Ayoub, Brian J Feldman, Kevin D G Pfleger

Get full text

Using nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time by Carl W. White, Hannah K. Vanyai, Heng B. See, Elizabeth K. M. Johnstone, Kevin D. G. Pfleger

Get full text

Investigation of Receptor Heteromers Using NanoBRET Ligand Binding by Elizabeth K. M. Johnstone, Heng B. See, Rekhati S. Abhayawardana, Angela Song, K. Johan Rosengren, Stephen J. Hill, Kevin D. G. Pfleger

Get full text

Insights into the Interaction of LVV-Hemorphin-7 with Angiotensin II Type 1 Receptor by Amanat Ali, Elizabeth K. M. Johnstone, Bincy Baby, Heng B. See, Angela Song, K. Johan Rosengren, Kevin D. G. Pfleger, Mohammed Akli Ayoub, Ranjit Vijayan

Get full text

Deleterious GRM1 mutations in schizophrenia. by Mohammed Akli Ayoub, Dora Angelicheva, David Vile, David Chandler, Bharti Morar, Juleen A Cavanaugh, Peter M Visscher, Assen Jablensky, Kevin D G Pfleger, Luba Kalaydjieva

Get full text

Homogeneous Time-Resolved Fluorescence-Based Assay to Monitor Extracellular Signal-Regulated Kinase Signalling in a High-Throughput Format by Mohammed Akli eAyoub, Julien eTrebaux, Julie eVallaghe, Fabienne eCharrier-Savournin, Khaled eAl-Hosaini, Arturo eGonzalez-Moya, Jean-Philippe R Pin, Kevin D G Pfleger, Eric eTrinquet

Get full text

The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer by Emily Golden, Rabab Rashwan, Eleanor A. Woodward, Agustin Sgro, Edina Wang, Anabel Sorolla, Charlene Waryah, Wan Jun Tie, Elisabet Cuyàs, Magdalena Ratajska, Iwona Kardaś, Piotr Kozlowski, Elizabeth K. M. Johnstone, Heng B. See, Ciara Duffy, Jeremy Parry, Kim A. Lagerborg, Piotr Czapiewski, Javier A. Menendez, Adam Gorczyński, Bartosz Wasag, Kevin D. G. Pfleger, Christina Curtis, Bum-Kyu Lee, Jonghwan Kim, Joseph Cursons, Nathan J. Pavlos, Wojciech Biernat, Mohit Jain, Andrew J. Woo, Andrew Redfern, Pilar Blancafort

Get full text