Structural similarities between SARS-CoV2 3CLpro and other viral proteases suggest potential lead molecules for developing broad spectrum antivirals by Khushboo Bafna, Khushboo Bafna, Christopher L. Cioffi, Robert M. Krug, Gaetano T. Montelione, Gaetano T. Montelione

Get full text

The bitter barricading of prostaglandin biosynthesis pathway: understanding the molecular mechanism of selective cyclooxygenase-2 inhibition by amarogentin, a secoiridoid glycoside... by Shantanu Shukla, Khushboo Bafna, Durai Sundar, Sunil S Thorat

Get full text

Nucleotide substrate binding characterization in human pancreatic-type ribonucleases. by Khushboo Bafna, Chitra Narayanan, S Chakra Chennubhotla, Nicolas Doucet, Pratul K Agarwal

Get full text

Computational Structure-Based De Novo Design of Hypothetical Inhibitors against the Anti- Inflammatory Target COX-2. by Jaspreet Kaur Dhanjal, Anith Kumar Sreenidhi, Khushboo Bafna, Shashank Prakash Katiyar, Sukriti Goyal, Abhinav Grover, Durai Sundar

Get full text

Ligand-Induced Variations in Structural and Dynamical Properties Within an Enzyme Superfamily by Chitra Narayanan, David N. Bernard, Khushboo Bafna, Donald Gagné, Pratul K. Agarwal, Pratul K. Agarwal, Nicolas Doucet, Nicolas Doucet

Get full text

Protocol for production and purification of SARS-CoV-2 3CLpro by Luca Mazzei, Rebecca Greene-Cramer, Khushboo Bafna, Aleksandar Jovanovic, Anna De Falco, Thomas B. Acton, Catherine Ann Royer, Stefano Ciurli, Gaetano T. Montelione

Get full text

Hepatitis C virus drugs that inhibit SARS-CoV-2 papain-like protease synergize with remdesivir to suppress viral replication in cell culture by Khushboo Bafna, Kris White, Balasubramanian Harish, Romel Rosales, Theresa A. Ramelot, Thomas B. Acton, Elena Moreno, Thomas Kehrer, Lisa Miorin, Catherine A. Royer, Adolfo García-Sastre, Robert M. Krug, Gaetano T. Montelione

Get full text