Structural insights into the broad-spectrum antiviral target endoplasmic reticulum alpha-glucosidase II by Zitzmann, N, Caputo, AT, Alonzi, DS, Kiappes, JL, Struwe, WB, Cross, A, Basu, S, Darlot, B, Roversi, P

ToP-DNJ, a selective inhibitor of endoplasmic reticulum α-glucosidase II exhibiting anti-flaviviral activity by Kiappes, JL, Hill, ML, Alonzi, DS, Miller, JL, Iwaki, R, Sayce, AC, Caputo, AT, Kato, A, Zitzmann, N

N-substituted valiolamine derivatives as potent inhibitors of endoplasmic reticulum α-glucosidases I and II with antiviral activity by Karade, S, Hill, M, Kiappes, JL, Manne, R, Aakula, B, Zitzmann, N, Warfield, K, Treston, A, Mariuzza, R

Assessment of repurposed compounds against coronaviruses highlights the antiviral broad-spectrum activity of host-targeting iminosugars and confirms the activity of potent directly... by Brun, J, Arman, BY, Hill, ML, Kiappes, JL, Alonzi, DS, Makower, LL, Witt, KD, Gileadi, C, Rangel, V, Dwek, RA, Von Delft, A, Zitzmann, N

Targeting ER α-glucosidase I with a single-dose iminosugar treatment protects against lethal influenza and dengue virus infections by Warfield, K, Alonzi, DS, Hill, JC, Caputo, AT, Roversi, P, Kiappes, JL, Sheets, N, Duchars, M, Dwek, RA, Biggins, J, Barnard, D, Shresta, S, Treston, A, Zitzmann, N

Iminosugars inhibit dengue virus production via inhibition of ER alpha-glucosidases – not glycolipid processing enzymes by Sayce, AC, Alonzi, DS, Killingbeck, SS, Tyrrell, BE, Hill, ML, Caputo, AT, Iwaki, R, Kinami, K, Ide, D, Kiappes, JL, Beatty, PR, Kato, A, Harris, E, Dwek, RA, Miller, JL, Zitzmann, N

Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4 by Warfield, KL, Plummer, EM, Sayce, AC, Alonzi, DS, Tang, W, Tyrrell, BE, Hill, ML, Caputo, AT, Killingbeck, SS, Beatty, PR, Harris, E, Iwaki, R, Kinami, K, Ide, D, Kiappes, JL, Kato, A, Buck, MD, King, K, Eddy, W, Khaliq, M, Sampath, A, Treston, AM, Dwek, RA, Enterlein, SG, Miller, JL, Zitzmann, N, Ramstedt, U, Shresta, S

A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint by Guay, KP, Ibba, R, Kiappes, JL, Vasiljević, S, Bonì, F, De Benedictis, M, Zeni, I, Le Cornu, JD, Hensen, M, Chandran, AV, Kantsadi, AL, Caputo, AT, Blanco Capurro, JI, Bayo, Y, Hill, JC, Hudson, K, Lia, A, Brun, J, Withers, SG, Martí, M, Biasini, E, Santino, A, De Rosa, M, Milani, M, Modenutti, CP, Hebert, DN, Zitzmann, N, Roversi, P

Turning high-throughput structural biology into predictive inhibitor design by Saar, KL, McCorkindale, W, Fearon, D, Boby, M, Barr, H, Ben-Shmuel, A, London, N, von Delft, F, Chodera, JD, Lee, AA, Koekemoer, L, Krojer, T, Fairhead, M, MacLean, EM, Thompson, A, Smilova, MD, Wright, N, von Delft, A, Gileadi, C, Schofield, CJ, Salah, E, Malla, TR, Tumber, A, John, T, Vakonakis, I, Kantsadi, AL, Zitzmann, N, Brun, J, Kiappes, JL, Hill, M, Witt, KD, Alonzi, DS, Makower, LL, Giroud, C, Bennett, J, Fedorov, O, Morris, GM, Ferla, M, Carbery, A, Cattermole, E, Taylor, JC, Brewitz, L