Convergence of signalling pathways in innate immune responses and genetic forms of Parkinson’s disease by Adamantios Mamais, Alice Kaganovich, Kirsten Harvey

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LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same by Daniel C. Berwick, George R. Heaton, Sonia Azeggagh, Kirsten Harvey

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Time course of neuroinflammation after human stroke – a pilot study using co-registered PET and MRI by Lucio D’Anna, Graham Searle, Kirsten Harvey, Paul M. Matthews, Roland Veltkamp

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Validation of a rapid remote digital test for impaired cognition using clinical dementia rating and mini-mental state examination: An observational research study by Ali Alim-Marvasti, Ali Alim-Marvasti, Ali Alim-Marvasti, Narayan Kuleindiren, Kirsten Harvey, Kirsten Harvey, Matteo Ciocca, Matteo Ciocca, Aaron Lin, Aaron Lin, Hamzah Selim, Mohammad Mahmud, Mohammad Mahmud

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Extent of white matter lesion is associated with early hemorrhagic transformation in acute ischemic stroke related to atrial fibrillation by Lucio D'Anna, Filippos T. Filippidis, Kirsten Harvey, Marilena Marinescu, Paul Bentley, Eleni Korompoki, Roland Veltkamp

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Tissue specific LRRK2 interactomes reveal a distinct striatal functional unit. by Yibo Zhao, Nikoleta Vavouraki, Ruth C Lovering, Valentina Escott-Price, Kirsten Harvey, Patrick A Lewis, Claudia Manzoni

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Transcriptomics and weighted protein network analyses of the LRRK2 protein interactome reveal distinct molecular signatures for sporadic and LRRK2 Parkinson’s Disease by Yibo Zhao, Matthew Bracher-Smith, Yuelin Li, Kirsten Harvey, Valentina Escott-Price, Patrick A. Lewis, Claudia Manzoni

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A critical role for glycine transporters in hyperexcitability disorders by Robert J Harvey, Eloisa Carta, Brian R Pearce, Seo-Kyung Chung, Stéphane Supplisson, Mark I Rees, Mark I Rees, Kirsten Harvey

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Dysregulated Wnt and NFAT signaling in a Parkinson’s disease LRRK2 G2019S knock-in model by Andrea Wetzel, Si Hang Lei, Tiansheng Liu, Michael P. Hughes, Yunan Peng, Tristan McKay, Simon N. Waddington, Simone Grannò, Ahad A. Rahim, Kirsten Harvey

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Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis by George R. Heaton, Natalie Landeck, Adamantios Mamais, Mike A. Nalls, Jonathon Nixon-Abell, Ravindran Kumaran, Alexandra Beilina, Laura Pellegrini, Yan Li, Kirsten Harvey, Mark R. Cookson

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Distinct Mechanisms of Pathogenic DJ-1 Mutations in Mitochondrial Quality Control by Daniela Strobbe, Daniela Strobbe, Alexis A. Robinson, Kirsten Harvey, Lara Rossi, Caterina Ferraina, Caterina Ferraina, Valerio de Biase, Carlo Rodolfo, Robert J. Harvey, Robert J. Harvey, Michelangelo Campanella, Michelangelo Campanella, Michelangelo Campanella

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Mutation p.R356Q in the Collybistin Phosphoinositide Binding Site Is Associated With Mild Intellectual Disability by Tzu-Ting Chiou, Philip Long, Alexandra Schumann-Gillett, Venkateswarlu Kanamarlapudi, Stefan A. Haas, Kirsten Harvey, Megan L. O’Mara, Angel L. De Blas, Vera M. Kalscheuer, Robert J. Harvey, Robert J. Harvey

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The glycinergic system in human startle disease: a genetic screening approach by Jeff S Davies, Seo-Kyung Chung, Rhys H Thomas, Angela Robinson, Carrie L Hammond, Jonathan G L Mullins, Eloisa Carta, Brian R Pearce, Kirsten Harvey, Robert J Harvey, Mark I Rees, Mark I Rees

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Novel missense mutations in the glycine receptor β subunit gene (GLRB) in startle disease by Victoria M. James, Anna Bode, Seo-Kyung Chung, Jennifer L. Gill, Maartje Nielsen, Frances M. Cowan, Mihailo Vujic, Rhys H. Thomas, Mark I. Rees, Kirsten Harvey, Angelo Keramidas, Maya Topf, Ieke Ginjaar, Joseph W. Lynch, Robert J. Harvey

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Novel Missense Mutation A789V in IQSEC2 Underlies X-Linked Intellectual Disability in the MRX78 Family by Vera M. Kalscheuer, Vera M. Kalscheuer, Victoria M. James, Miranda L. Himelright, Philip Long, Renske Oegema, Corinna Jensen, Melanie Bienek, Hao Hu, Stefan A. Haas, Maya Topf, A. Jeannette M. Hoogeboom, Kirsten Harvey, Randall Walikonis, Robert J. Harvey

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Kinase activity is required for the toxic effects of mutant LRRK2/dardarin by Elisa Greggio, Shushant Jain, Ann Kingsbury, Rina Bandopadhyay, Patrick Lewis, Alice Kaganovich, Marcel P. van der Brug, Alexandra Beilina, Jeff Blackinton, Kelly Jean Thomas, Rili Ahmad, David W. Miller, Sashi Kesavapany, Andrew Singleton, Andrew Lees, Robert J. Harvey, Kirsten Harvey, Mark R. Cookson

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The Parkinson’s Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network by Alexandra Beilina, Luis Bonet-Ponce, Ravindran Kumaran, Jennifer J. Kordich, Morié Ishida, Adamantios Mamais, Alice Kaganovich, Sara Saez-Atienzar, David C. Gershlick, Dorien A. Roosen, Laura Pellegrini, Vlad Malkov, Matthew J. Fell, Kirsten Harvey, Juan S. Bonifacino, Darren J. Moore, Mark R. Cookson

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Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia. by Adamantios Mamais, Jillian H Kluss, Luis Bonet-Ponce, Natalie Landeck, Rebekah G Langston, Nathan Smith, Alexandra Beilina, Alice Kaganovich, Manik C Ghosh, Laura Pellegrini, Ravindran Kumaran, Ioannis Papazoglou, George R Heaton, Kirsten Harvey, Rina Bandopadhyay, Nunziata Maio, Changyoun Kim, Matthew J LaVoie, David C Gershlick, Mark R Cookson

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