Targeting Tuberculosis and HIV Infection-Specific Regulatory T Cells with MEK/ERK Signaling Pathway Inhibitors. by Nora V Lieske, Kristian Tonby, Dag Kvale, Anne M Dyrhol-Riise, Kjetil Tasken

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Acta Oncologica Nordic Precision Cancer Medicine Symposium 2023 – merging clinical research and standard healthcare by Elisa Bjørgo, Gro L. Fagereng, Hege G. Russnes, Sigbjørn Smeland, Kjetil Taskén, Åslaug Helland

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The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection by Kristian Tonby, Ida Wergeland, Nora V. Lieske, Dag Kvale, Kjetil Tasken, Anne M. Dyrhol-Riise

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Enhanced Gut-Homing Dynamics and Pronounced Exhaustion of Mucosal and Blood CD4+ T Cells in HIV-Infected Immunological Non-Responders by Kristina Berg Lorvik, Kristina Berg Lorvik, Kristina Berg Lorvik, Malin Holm Meyer-Myklestad, Malin Holm Meyer-Myklestad, Kushi Kushekar, Kushi Kushekar, Charlotte Handeland, Asle Wilhelm Medhus, Marius Lund-Iversen, Birgitte Stiksrud, Dag Kvale, Dag Kvale, Anne Margarita Dyrhol-Riise, Anne Margarita Dyrhol-Riise, Kjetil Taskén, Kjetil Taskén, Kjetil Taskén, Dag Henrik Reikvam, Dag Henrik Reikvam

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Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients by Marthe Jøntvedt Jørgensen, Marthe Jøntvedt Jørgensen, Kristin G. Nore, Hans Christian D. Aass, Emilie Layre, Jérôme Nigou, Rasmus Mortensen, Kjetil Tasken, Kjetil Tasken, Dag Kvale, Synne Jenum, Kristian Tonby, Kristian Tonby, Anne Ma Dyrhol-Riise, Anne Ma Dyrhol-Riise

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Patient‐derived acellular ascites fluid affects drug responses in ovarian cancer cell lines through the activation of key signalling pathways by Katharina Bischof, Andrea Cremaschi, Lena Eroukhmanoff, Johannes Landskron, Lise‐Lotte Flage‐Larsen, Alexandra Gade, Line Bjørge, Alfonso Urbanucci, Kjetil Taskén

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Spleen tyrosine kinase inhibitors reduce CD40L-induced proliferation of chronic lymphocytic leukemia cells but not normal B cells by Anna Parente-Ribes, Sigrid S. Skånland, Simone Bürgler, Audun Os, Dong Wang, Bjarne Bogen, Geir E. Tjønnfjord, Kjetil Taskén, Ludvig A. Munthe

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Ex vivo drug sensitivity screening in multiple myeloma identifies drug combinations that act synergistically by Mariaserena Giliberto, Deepak B. Thimiri Govinda Raj, Andrea Cremaschi, Sigrid S. Skånland, Alexandra Gade, Geir E. Tjønnfjord, Fredrik Schjesvold, Ludvig A. Munthe, Kjetil Taskén

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Mcl‐1 and Bcl‐xL levels predict responsiveness to dual MEK/Bcl‐2 inhibition in B‐cell malignancies by Katrine Melvold, Mariaserena Giliberto, Linda Karlsen, Pilar Ayuda‐Durán, Robert Hanes, Toril Holien, Jorrit Enserink, Jennifer R. Brown, Geir E. Tjønnfjord, Kjetil Taskén, Sigrid S. Skånland

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C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease. by Johannes Landskron, Sigrid M Kraggerud, Elisabeth Wik, Anne Dørum, Merete Bjørnslett, Espen Melum, Øystein Helland, Line Bjørge, Ragnhild A Lothe, Helga B Salvesen, Kjetil Taskén

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A tumor microenvironment model of chronic lymphocytic leukemia enables drug sensitivity testing to guide precision medicine by Johanne U. Hermansen, Yanping Yin, Aleksandra Urban, Camilla V. Myklebust, Linda Karlsen, Katrine Melvold, Anders A. Tveita, Kjetil Taskén, Ludvig A. Munthe, Geir E. Tjønnfjord, Sigrid S. Skånland

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P613: ANALYSIS OF EX-VIVO RESPONSE TO SINGLE DRUGS AND DRUG COMBINATIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA PATIENT SAMPLES by Leonardo Miranda Santana, Deepak B. Thimiri Govinda Raj, Andrea Cremaschi, Mariaserena Giliberto, Alexandra Gade, Arnoldo Frigessi, Geir E. Tjønnfjord, Ludvig A. Munthe, Sigrid S. Skånland, Manuela Zucknick, Kjetil Taskén

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Sensing of HIV-1 by TLR8 activates human T cells and reverses latency by Hany Zekaria Meås, Markus Haug, Marianne Sandvold Beckwith, Claire Louet, Liv Ryan, Zhenyi Hu, Johannes Landskron, Svein Arne Nordbø, Kjetil Taskén, Hang Yin, Jan Kristian Damås, Trude Helen Flo

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Standardized assays to monitor drug sensitivity in hematologic cancers by Pilar Ayuda-Durán, Johanne U. Hermansen, Mariaserena Giliberto, Yanping Yin, Robert Hanes, Sandra Gordon, Heikki Kuusanmäki, Andrea M. Brodersen, Aram N. Andersen, Kjetil Taskén, Krister Wennerberg, Jorrit M. Enserink, Sigrid S. Skånland

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A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients by Synne Jenum, Kristian Tonby, Corina S. Rueegg, Morten Rühwald, Max P. Kristiansen, Peter Bang, Inge Christoffer Olsen, Kjersti Sellæg, Kjerstin Røstad, Tehmina Mustafa, Kjetil Taskén, Dag Kvale, Rasmus Mortensen, Anne Ma Dyrhol-Riise

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Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines by Mariaserena Giliberto, Mariaserena Giliberto, Leonardo Miranda Santana, Leonardo Miranda Santana, Leonardo Miranda Santana, Toril Holien, Toril Holien, Toril Holien, Kristine Misund, Sigve Nakken, Sigve Nakken, Sigve Nakken, Daniel Vodak, Daniel Vodak, Daniel Vodak, Eivind Hovig, Eivind Hovig, Eivind Hovig, Leonardo A. Meza-Zepeda, Leonardo A. Meza-Zepeda, Leonardo A. Meza-Zepeda, Eivind Coward, Eivind Coward, Anders Waage, Anders Waage, Anders Waage, Kjetil Taskén, Kjetil Taskén, Sigrid S. Skånland, Sigrid S. Skånland

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Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation by Safak Caglayan, Adnan Hashim, Artur Cieslar-Pobuda, Vidar Jensen, Sidney Behringer, Burcu Talug, Dinh Toi Chu, Christian Pecquet, Marie Rogne, Andreas Brech, Sverre Henning Brorson, Erlend Arnulf Nagelhus, Luciana Hannibal, Antonella Boschi, Kjetil Taskén, Judith Staerk

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The effect of HLA genotype on disease onset and severity in CTLA-4 insufficiency by Sara Posadas-Cantera, Sara Posadas-Cantera, Noriko Mitsuiki, Florian Emmerich, Virginia Patiño, Hanns-Martin Lorenz, Olaf Neth, Ingunn Dybedal, Kjetil Taskén, Alejandro A. Schäffer, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher, Laura Gámez-Díaz, Laura Gámez-Díaz

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Aspirin as secondary prevention in colorectal cancer liver metastasis (ASAC trial): study protocol for a multicentre randomized placebo-controlled trial by Sheraz Yaqub, Bjørn Atle Bjørnbeth, Jon-Helge Angelsen, Claus Wilki Fristrup, Jon Erik Grønbech, Oskar Hemmingsson, Bengt Isaksson, Ingebjørg Soterud Juel, Peter Nørgaard Larsen, Gert Lindell, Frank Viborg Mortensen, Kim Erlend Mortensen, Magnus Rizell, Per Sandström, Oddvar Mathias Sandvik, Ernesto Sparrelid, Helena Taflin, Kjetil Taskén, The ASAC study group

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Remodeling of secretory lysosomes during education tunes functional potential in NK cells by Jodie P. Goodridge, Benedikt Jacobs, Michelle L. Saetersmoen, Dennis Clement, Quirin Hammer, Trevor Clancy, Ellen Skarpen, Andreas Brech, Johannes Landskron, Christian Grimm, Aline Pfefferle, Leonardo Meza-Zepeda, Susanne Lorenz, Merete Thune Wiiger, William E. Louch, Eivind Heggernes Ask, Lisa L. Liu, Vincent Yi Sheng Oei, Una Kjällquist, Sten Linnarsson, Sandip Patel, Kjetil Taskén, Harald Stenmark, Karl-Johan Malmberg

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