All Good Things Come to an End: 5 Years at the Helm of CMGH by Klaus H. Kaestner, Michael Pack

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The Role of Non-Coding RNAs in Liver Disease, Injury, and Regeneration by Melissa M. Rowe, Klaus H. Kaestner

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Mammalian Intestinal Development and Differentiation—The State of the ArtSummary by Hannah M. Kolev, Klaus H. Kaestner

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Benchmarking algorithms for joint integration of unpaired and paired single-cell RNA-seq and ATAC-seq data by Michelle Y. Y. Lee, Klaus H. Kaestner, Mingyao Li

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The ‘de novo’ DNA methyltransferase Dnmt3b compensates the Dnmt1-deficient intestinal epithelium by Ellen N Elliott, Karyn L Sheaffer, Klaus H Kaestner

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H3K27me3 Demethylases Maintain the Transcriptional and Epigenomic Landscape of the Intestinal EpitheliumSummary by Hannah M. Kolev, Avital Swisa, Elisabetta Manduchi, Yemin Lan, Rachel R. Stine, Giuseppe Testa, Klaus H. Kaestner

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Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2. by Irina M Bochkis, Jonathan Schug, Diana Z Ye, Svitlana Kurinna, Sabrina A Stratton, Michelle C Barton, Klaus H Kaestner

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Telocyte Recruitment During the Emergence of a Metaplastic Niche in the StomachSummary by Yoojin Sohn, Blake Flores Semyonov, Hilana El-Mekkoussi, Christopher V.E. Wright, Klaus H. Kaestner, Eunyoung Choi, James R. Goldenring

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Disruption of CHTF18 causes defective meiotic recombination in male mice. by Karen M Berkowitz, Aislinn R Sowash, Lydia R Koenig, Dawnette Urcuyo, Fahmida Khan, Fang Yang, P Jeremy Wang, Thomas A Jongens, Klaus H Kaestner

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Telomouse—a mouse model with human-length telomeres generated by a single amino acid change in RTEL1 by Riham Smoom, Catherine Lee May, Vivian Ortiz, Mark Tigue, Hannah M. Kolev, Melissa Rowe, Yitzhak Reizel, Ashleigh Morgan, Nachshon Egyes, Dan Lichtental, Emmanuel Skordalakes, Klaus H. Kaestner, Yehuda Tzfati

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Advanced precision modeling reveals divergent responses of hepatocellular carcinoma to combinatorial immunotherapy by Jinping Liu, Lan Cheng, Hilana El‐Mekkoussi, Charles‐Antoine Assenmacher, Michelle Y. Y. Lee, Danielle R. Jaffe, Kaisha Garvin‐Darby, Ashleigh Morgan, Elisabetta Manduchi, Jonathan Schug, Klaus H. Kaestner

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AnnoSpat annotates cell types and quantifies cellular arrangements from spatial proteomics by Aanchal Mongia, Fatema Tuz Zohora, Noah G. Burget, Yeqiao Zhou, Diane C. Saunders, Yue J. Wang, Marcela Brissova, Alvin C. Powers, Klaus H. Kaestner, Golnaz Vahedi, Ali Naji, Gregory W. Schwartz, Robert B. Faryabi

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Intra-islet α-cell Gs signaling promotes glucagon release by Liu Liu, Kimberley El, Diptadip Dattaroy, Luiz F. Barella, Yinghong Cui, Sarah M. Gray, Carla Guedikian, Min Chen, Lee S. Weinstein, Emily Knuth, Erli Jin, Matthew J. Merrins, Jeffrey Roman, Klaus H. Kaestner, Nicolai Doliba, Jonathan E. Campbell, Jürgen Wess

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Author Correction: Intra-islet α-cell Gs signaling promotes glucagon release by Liu Liu, Kimberley EI, Diptadip Dattaroy, Luiz F. Barella, Yinghong Cui, Sarah M. Gray, Carla Guedikian, Min Chen, Lee S. Weinstein, Emily Knuth, Erli Jin, Matthew J. Merrins, Jeffrey Roman, Klaus H. Kaestner, Nicolai Doliba, Jonathan E. Campbell, Jürgen Wess

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Adaptation to chronic ER stress enforces pancreatic β-cell plasticity by Chien-Wen Chen, Bo-Jhih Guan, Mohammed R. Alzahrani, Zhaofeng Gao, Long Gao, Syrena Bracey, Jing Wu, Cheikh A. Mbow, Raul Jobava, Leena Haataja, Ajay H. Zalavadia, Ashleigh E. Schaffer, Hugo Lee, Thomas LaFramboise, Ilya Bederman, Peter Arvan, Clayton E. Mathews, Ivan C. Gerling, Klaus H. Kaestner, Boaz Tirosh, Feyza Engin, Maria Hatzoglou

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3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity by Khanh B Trang, Matthew C Pahl, James A Pippin, Chun Su, Sheridan H Littleton, Prabhat Sharma, Nikhil N Kulkarni, Louis R Ghanem, Natalie A Terry, Joan M O'Brien, Yadav Wagley, Kurt D Hankenson, Ashley Jermusyk, Jason Hoskins, Laufey T Amundadottir, Mai Xu, Kevin Brown, Stewart Anderson, Wenli Yang, Paul Titchenell, Patrick Seale, Klaus H Kaestner, Laura Cook, Megan Levings, Babette S Zemel, Alessandra Chesi, Andrew D Wells, Struan FA Grant

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