Metabolic inflexibility of mitochondria: beneficial for the fitness of regenerating liver cells by Josef Ecker, Sarah Brunner, Klaus-Peter Janssen

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Post-fast refeeding: rise of intestinal stemness and mutagen-induced cancer risk through polyamine metabolism by Sarah Brunner, Klaus-Peter Janssen, Josef Ecker

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Boosting liver regeneration: kinase inhibitor as a new tool to prevent liver failure by Anna Sichler, Norbert Hüser, Klaus-Peter Janssen

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Liver regeneration in fatty liver disease: can metabolomics shed light on the contribution of the gut microbiome? by Florian Jokisch, Laura Jennifer Marie Geyer, Klaus-Peter Janssen

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Increased Incidence of Colon Tumors in AOM-Treated Apc1638N/+ Mice Reveals Higher Frequency of Tumor Associated Neutrophils in Colon Than Small Intestine by Rebecca Metzger, Mahulena Maruskova, Sabrina Krebs, Klaus-Peter Janssen, Anne B. Krug

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MRTF-A gain-of-function in mice impairs homeostatic renewal of the intestinal epithelium by Anurag Kumar Singh, Amrita Rai, Anja Weber, Martin Gericke, Klaus-Peter Janssen, Markus Moser, Guido Posern

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Differences in Gut Virome Related to Barrett Esophagus and Esophageal Adenocarcinoma by Tianli Ma, Jinlong Ru, Jinling Xue, Sarah Schulz, Mohammadali Khan Mirzaei, Klaus-Peter Janssen, Michael Quante, Li Deng

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Specific miRNAs are associated with human cancer cachexia in an organ‐specific manner by Tanja Krauss, Simone Heisz, Julius Honecker, Olga Prokopchuk, Marc Martignoni, Klaus‐Peter Janssen, Melina Claussnitzer, Hans Hauner, Claudine Seeliger

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Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer by Teresa Friedrich, Michaela Söhn, Tobias Gutting, Klaus-Peter Janssen, Hans-Michael Behrens, Christoph Röcken, Matthias P.A. Ebert, Elke Burgermeister

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The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial–Mesenchymal Transition and Metastasis in Colorectal CancerSummary by Fabian Christoph Franke, Johannes Müller, Miguel Abal, Eduardo Domínguez Medina, Ulrich Nitsche, Henri Weidmann, Solenne Chardonnet, Ewa Ninio, Klaus-Peter Janssen

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Diabetes increases mortality in patients with pancreatic and colorectal cancer by promoting cachexia and its associated inflammatory status by Alexandra Chovsepian, Olga Prokopchuk, Gabriela Petrova, Tefta Gjini, Hanna Kuzi, Simone Heisz, Klaus-Peter Janssen, Marc E. Martignoni, Helmut Friess, Hans Hauner, Maria Rohm

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Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction by Thomas Kunzke, Achim Buck, Verena M. Prade, Annette Feuchtinger, Olga Prokopchuk, Marc E. Martignoni, Simone Heisz, Hans Hauner, Klaus‐Peter Janssen, Axel Walch, Michaela Aichler

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Genetic and immunological biomarkers predict metastatic disease recurrence in stage III colon cancer by Andreas Sperlich, Alexander Balmert, Dietrich Doll, Sabine Bauer, Fabian Franke, Gisela Keller, Dirk Wilhelm, Anna Mur, Michael Respondek, Helmut Friess, Ulrich Nitsche, Klaus-Peter Janssen

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Targeting myeloid derived suppressor cells with all-trans retinoic acid is highly time-dependent in therapeutic tumor vaccination by Annkristin Heine, Chrystel Flores, Heidrun Gevensleben, Linda Diehl, Mathias Heikenwalder, Marc Ringelhan, Klaus-Peter Janssen, Ulrich Nitsche, Natalio Garbi, Peter Brossart, Percy A. Knolle, Christian Kurts, Bastian Höchst

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PPARγ-activation increases intestinal M1 macrophages and mitigates formation of serrated adenomas in mutant KRAS mice by Tobias Gutting, Christian A. Weber, Philip Weidner, Frank Herweck, Sarah Henn, Teresa Friedrich, Shuiping Yin, Julia Kzhyshkowska, Timo Gaiser, Klaus-Peter Janssen, Wolfgang Reindl, Matthias P. A. Ebert, Elke Burgermeister

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Bacillamide D produced by Bacillus cereus from the mouse intestinal bacterial collection (miBC) is a potent cytotoxin in vitro by Maximilian Hohmann, Valentina Brunner, Widya Johannes, Dominik Schum, Laura M. Carroll, Tianzhe Liu, Daisuke Sasaki, Johanna Bosch, Thomas Clavel, Stephan A. Sieber, Georg Zeller, Markus Tschurtschenthaler, Klaus-Peter Janßen, Tobias A. M. Gulder

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Gut Microbial Disruption in Critically Ill Patients with COVID-19-Associated Pulmonary Aspergillosis by H. Carlo Maurer, David Schult, Plamena Koyumdzhieva, Sandra Reitmeier, Moritz Middelhoff, Sebastian Rasch, Markus List, Klaus-Peter Janssen, Katja Steiger, Ulrike Protzer, Roland M. Schmid, Klaus Neuhaus, Dirk Haller, Michael Quante, Tobias Lahmer

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A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations by Michael Buchert, Franziska Rohde, Moritz Eissmann, Niall Tebbutt, Ben Williams, Chin Wee Tan, Alexander Owen, Yumiko Hirokawa, Alexandra Gnann, Gertraud Orend, Gayle Orner, Rod H. Dashwood, Joan K. Heath, Matthias Ernst, Klaus-Peter Janssen

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Universal, untargeted detection of bacteria in tissues using metabolomics workflows by Wei Chen, Min Qiu, Petra Paizs, Miriam Sadowski, Toma Ramonaite, Lieby Zborovsky, Raquel Mejias-Luque, Klaus-Peter Janßen, James Kinross, Robert D. Goldin, Monica Rebec, Manuel Liebeke, Zoltan Takats, James S. McKenzie, Nicole Strittmatter

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Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling by Nicolas Aznar, Krishna K Midde, Ying Dunkel, Inmaculada Lopez-Sanchez, Yelena Pavlova, Arthur Marivin, Jorge Barbazán, Fiona Murray, Ulrich Nitsche, Klaus-Peter Janssen, Karl Willert, Ajay Goel, Miguel Abal, Mikel Garcia-Marcos, Pradipta Ghosh

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