The Mitochondrial Permeability Transition Pore Regulator Cyclophilin D Exhibits Tissue-Specific Control of Metabolic Homeostasis. by Rhianna C Laker, Evan P Taddeo, Yasir N Akhtar, Mei Zhang, Kyle L Hoehn, Zhen Yan

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Acetyl CoA Carboxylase 2 Is Dispensable for CD8+ T Cell Responses. by Jang Eun Lee, Matthew C Walsh, Kyle L Hoehn, David E James, E John Wherry, Yongwon Choi

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Complete inhibition of liver acetyl-CoA carboxylase activity is required to exacerbate liver tumorigenesis in mice treated with diethylnitrosamine by Riya Shrestha, Calum S. Vancuylenburg, Martina Beretta, Mingyan Zhou, Divya P. Shah, Ellen M. Olzomer, Sian L. Richards, Kyle L. Hoehn, Frances L. Byrne

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Delivering bioactive cyclic peptides that target Hsp90 as prodrugs by Yuantao Huo, Laura K. Buckton, Jack L. Bennett, Eloise C. Smith, Frances L. Byrne, Kyle L. Hoehn, Marwa N. Rahimi, Shelli R. McAlpine

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Mitochondrial Uncoupler BAM15 Ameliorates Associated Metabolic PCOS Traits in a Hyperandrogenic PCOS Mouse Model by Valentina RODRIGUEZ PARIS, Stephanie J. ALEXOPOULOS, Ying HU, Divya P. SHAH, Ali AFLATOUNIAN, Melissa C. EDWARDS, Michael J. BERTOLDO, Robert B. GILCHRIST, Kyle L. HOEHN, Kirsty A. WALTERS

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Lysophosphatidic acid counteracts glucagon-induced hepatocyte glucose production via STAT3 by Evan P. Taddeo, Stefan R. Hargett, Sujoy Lahiri, Marin E. Nelson, Jason A. Liao, Chien Li, Jill K. Slack-Davis, Jose L. Tomsig, Kevin R. Lynch, Zhen Yan, Thurl E. Harris, Kyle L. Hoehn

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Distinct Roles for Intracellular and Extracellular Lipids in Hepatitis C Virus Infection. by Sowmya Narayanan, Albert H Nieh, Brandon M Kenwood, Christine A Davis, Annie-Carole Tosello-Trampont, Tedd D Elich, Steven D Breazeale, Eric Ward, Richard J Anderson, Stephen H Caldwell, Kyle L Hoehn, Young S Hahn

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Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3) by Alexander J. Knights, Emily J. Vohralik, Peter J. Houweling, Elizabeth S. Stout, Laura J. Norton, Stephanie J. Alexopoulos, Jinfen. J. Yik, Hanapi Mat Jusoh, Ellen M. Olzomer, Kim S. Bell-Anderson, Kathryn N. North, Kyle L. Hoehn, Merlin Crossley, Kate G. R. Quinlan

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Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival by Marin E. Nelson, Sujoy Lahiri, Jenny D. Y. Chow, Frances L. Byrne, Stefan R. Hargett, David S. Breen, Ellen M. Olzomer, Lindsay E. Wu, Gregory J. Cooney, Nigel Turner, David E. James, Jill K. Slack-Davis, Carolin Lackner, Stephen H. Caldwell, Kyle L. Hoehn

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Acetyl-CoA-carboxylase 1 (ACC1) plays a critical role in glucagon secretion by Anna Veprik, Geoffrey Denwood, Dong Liu, Rula Bany Bakar, Valentin Morfin, Kara McHugh, Nchimunya N. Tebeka, Laurène Vetterli, Ekaterina Yonova-Doing, Fiona Gribble, Frank Reimann, Kyle L. Hoehn, Piers A. Hemsley, Jonas Ahnfelt-Rønne, Patrik Rorsman, Quan Zhang, Heidi de Wet, James Cantley

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Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15 by Elizabeth R. M. Zunica, Christopher L. Axelrod, Eunhan Cho, Guillaume Spielmann, Gangarao Davuluri, Stephanie J. Alexopoulos, Martina Beretta, Kyle L. Hoehn, Wagner S. Dantas, Krisztian Stadler, William T. King, Kathryn Pergola, Brian A. Irving, Ingeborg M. Langohr, Shengping Yang, Charles L. Hoppel, L. Anne Gilmore, John P. Kirwan

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Targeting negative energy balance with calorie restriction and mitochondrial uncoupling in db/db mice by Sing-Young Chen, Martina Beretta, Ellen M. Olzomer, Divya P. Shah, Derek Y.H. Wong, Stephanie J. Alexopoulos, Isabella Aleksovska, Joseph M. Salamoun, Christopher J. Garcia, Blake J. Cochran, Kerry-Anne Rye, Greg C. Smith, Frances L. Byrne, Margaret J. Morris, Webster L. Santos, James Cantley, Kyle L. Hoehn

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Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism by James R. Krycer, Katsuyuki Yugi, Akiyoshi Hirayama, Daniel J. Fazakerley, Lake-Ee Quek, Richard Scalzo, Satoshi Ohno, Mark P. Hodson, Satsuki Ikeda, Futaba Shoji, Kumi Suzuki, Westa Domanova, Benjamin L. Parker, Marin E. Nelson, Sean J. Humphrey, Nigel Turner, Kyle L. Hoehn, Gregory J. Cooney, Tomoyoshi Soga, Shinya Kuroda, David E. James

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BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control by Christopher L Axelrod, William T King, Gangarao Davuluri, Robert C Noland, Jacob Hall, Michaela Hull, Wagner S Dantas, Elizabeth RM Zunica, Stephanie J Alexopoulos, Kyle L Hoehn, Ingeborg Langohr, Krisztian Stadler, Haylee Doyle, Eva Schmidt, Stephan Nieuwoudt, Kelly Fitzgerald, Kathryn Pergola, Hisashi Fujioka, Jacob T Mey, Ciaran Fealy, Anny Mulya, Robbie Beyl, Charles L Hoppel, John P Kirwan

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Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet by Belinda Yau, Sheyda Naghiloo, Alexis Diaz-Vegas, Austin V. Carr, Julian Van Gerwen, Elise J. Needham, Dillon Jevon, Sing-Young Chen, Kyle L. Hoehn, Amanda E. Brandon, Laurence Macia, Gregory J. Cooney, Michael R. Shortreed, Lloyd M. Smith, Mark P. Keller, Peter Thorn, Mark Larance, David E. James, Sean J. Humphrey, Melkam A. Kebede

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Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet by Belinda Yau, Sheyda Naghiloo, Alexis Diaz-Vegas, Austin V. Carr, Julian Van Gerwen, Elise J. Needham, Dillon Jevon, Sing-Young Chen, Kyle L. Hoehn, Amanda E. Brandon, Laurence Macia, Gregory J. Cooney, Michael R. Shortreed, Lloyd M. Smith, Mark P. Keller, Peter Thorn, Mark Larance, David E. James, Sean J. Humphrey, Melkam A. Kebede

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Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice by Stephanie J. Alexopoulos, Sing-Young Chen, Amanda E. Brandon, Joseph M. Salamoun, Frances L. Byrne, Christopher J. Garcia, Martina Beretta, Ellen M. Olzomer, Divya P. Shah, Ashleigh M. Philp, Stefan R. Hargett, Robert T. Lawrence, Brendan Lee, James Sligar, Pascal Carrive, Simon P. Tucker, Andrew Philp, Carolin Lackner, Nigel Turner, Gregory J. Cooney, Webster L. Santos, Kyle L. Hoehn

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A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism by Nigel Turner, Xin Ying Lim, Hamish D. Toop, Brenna Osborne, Amanda E. Brandon, Elysha N. Taylor, Corrine E. Fiveash, Hemna Govindaraju, Jonathan D. Teo, Holly P. McEwen, Timothy A. Couttas, Stephen M. Butler, Abhirup Das, Greg M. Kowalski, Clinton R. Bruce, Kyle L. Hoehn, Thomas Fath, Carsten Schmitz-Peiffer, Gregory J. Cooney, Magdalene K. Montgomery, Jonathan C. Morris, Anthony S. Don

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Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance by Daniel J Fazakerley, Rima Chaudhuri, Pengyi Yang, Ghassan J Maghzal, Kristen C Thomas, James R Krycer, Sean J Humphrey, Benjamin L Parker, Kelsey H Fisher-Wellman, Christopher C Meoli, Nolan J Hoffman, Ciana Diskin, James G Burchfield, Mark J Cowley, Warren Kaplan, Zora Modrusan, Ganesh Kolumam, Jean YH Yang, Daniel L Chen, Dorit Samocha-Bonet, Jerry R Greenfield, Kyle L Hoehn, Roland Stocker, David E James

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Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress by Frances L. Byrne, Ellen M. Olzomer, Gabriella R. Marriott, Lake-Ee Quek, Alice Katen, Jacky Su, Marin E. Nelson, Gene Hart-Smith, Mark Larance, Veronica F. Sebesfi, Jeff Cuff, Gabriella E. Martyn, Elizabeth Childress, Stephanie J. Alexopoulos, Ivan K. Poon, Maree C. Faux, Antony W. Burgess, Glen Reid, Joshua A. McCarroll, Webster L. Santos, Kate GR. Quinlan, Nigel Turner, Daniel J. Fazakerley, Naresh Kumar, Kyle L. Hoehn

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