Myosin VI Contains a Compact Structural Motif that Binds to Ubiquitin Chains by Fahu He, Hans-Peter Wollscheid, Urszula Nowicka, Matteo Biancospino, Eleonora Valentini, Aaron Ehlinger, Filippo Acconcia, Elisa Magistrati, Simona Polo, Kylie J. Walters

Get full text

Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension by Matteo Biancospino, Gwen R. Buel, Carlos A. Niño, Elena Maspero, Rossella Scotto di Perrotolo, Andrea Raimondi, Lisa Redlingshöfer, Janine Weber, Frances M. Brodsky, Kylie J. Walters, Simona Polo

Get full text

Structure of E3 ligase E6AP with a proteasome-binding site provided by substrate receptor hRpn10 by Gwen R. Buel, Xiang Chen, Raj Chari, Maura J. O’Neill, Danielle L. Ebelle, Conor Jenkins, Vinidhra Sridharan, Sergey G. Tarasov, Nadya I. Tarasova, Thorkell Andresson, Kylie J. Walters

Get full text

Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer by Ravi K. Anchoori, Rosie Jiang, Shiwen Peng, Ruey-shyang Soong, Aliyah Algethami, Michelle A. Rudek, Nicole Anders, Chien-Fu Hung, Xiang Chen, Xiuxiu Lu, Olumide Kayode, Marzena Dyba, Kylie J. Walters, Richard B. S. Roden

Get full text

A planar polarized MYO6-DOCK7-RAC1 axis promotes tissue fluidification in mammary epithelia by Luca Menin, Janine Weber, Stefano Villa, Emanuele Martini, Elena Maspero, Carlos A. Niño, Valeria Cancila, Alessandro Poli, Paolo Maiuri, Andrea Palamidessi, Emanuela Frittoli, Fabrizio Bianchi, Claudio Tripodo, Kylie J. Walters, Fabio Giavazzi, Giorgio Scita, Simona Polo

Get full text

Structural and photophysical characterization of the small ultra-red fluorescent protein by Atanu Maiti, Cosmo Z. Buffalo, Saumya Saurabh, Felipe Montecinos-Franjola, Justin S. Hachey, William J. Conlon, Geraldine N. Tran, Bakar Hassan, Kylie J. Walters, Mikhail Drobizhev, W. E. Moerner, Partho Ghosh, Hiroshi Matsuo, Roger Y. Tsien, John Y. Lin, Erik A. Rodriguez

Get full text

Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex by David R. Calabrese, Xiang Chen, Elena C. Leon, Snehal M. Gaikwad, Zaw Phyo, William M. Hewitt, Stephanie Alden, Thomas A. Hilimire, Fahu He, Aleksandra M. Michalowski, John K. Simmons, Lindsey B. Saunders, Shuling Zhang, Daniel Connors, Kylie J. Walters, Beverly A. Mock, John S. Schneekloth

Get full text

Metabolic plasticity of IDH1-mutant glioma cell lines is responsible for low sensitivity to glutaminase inhibition by Victor Ruiz-Rodado, Adrian Lita, Tyrone Dowdy, Orieta Celiku, Alejandra Cavazos Saldana, Herui Wang, Chun Zhang Yang, Raj Chari, Aiguo Li, Wei Zhang, Hua Song, Meili Zhang, Susie Ahn, Dionne Davis, Xiang Chen, Zhengping Zhuang, Christel Herold-Mende, Kylie J. Walters, Mark R. Gilbert, Mioara Larion

Get full text

A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins by Xiuxiu Lu, Monika Chandravanshi, Venkata R. Sabbasani, Snehal Gaikwad, V. Keith Hughitt, Nana Gyabaah-Kessie, Bradley T. Scroggins, Sudipto Das, Wazo Myint, Michelle E. Clapp, Charles D. Schwieters, Marzena A. Dyba, Derek L. Bolhuis, Janusz W. Koscielniak, Thorkell Andresson, Michael J. Emanuele, Nicholas G. Brown, Hiroshi Matsuo, Raj Chari, Deborah E. Citrin, Beverly A. Mock, Rolf E. Swenson, Kylie J. Walters

Get full text

Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation by Andrea Accogli, Saurabh Shakya, Taewoo Yang, Christine Insinna, Soo Yeon Kim, David Bell, Kirill R. Butov, Mariasavina Severino, Marcello Niceta, Marcello Scala, Hyun Sik Lee, Taekyeong Yoo, Jimmy Stauffer, Huijie Zhao, Chiara Fiorillo, Marina Pedemonte, Maria C. Diana, Simona Baldassari, Viktoria Zakharova, Anna Shcherbina, Yulia Rodina, Christina Fagerberg, Laura Sønderberg Roos, Jolanta Wierzba, Artur Dobosz, Amanda Gerard, Lorraine Potocki, Jill A. Rosenfeld, Seema R. Lalani, Tiana M. Scott, Daryl Scott, Mahshid S. Azamian, Raymond Louie, Hannah W. Moore, Neena L. Champaigne, Grace Hollingsworth, Annalaura Torella, Vincenzo Nigro, Rafal Ploski, Vincenzo Salpietro, Federico Zara, Simone Pizzi, Giovanni Chillemi, Marzia Ognibene, Erin Cooney, Jenny Do, Anders Linnemann, Martin J. Larsen, Suzanne Specht, Kylie J. Walters, Hee-Jung Choi, Murim Choi, Marco Tartaglia, Phillippe Youkharibache, Jong-Hee Chae, Valeria Capra, Sung-Gyoo Park, Christopher J. Westlake

Get full text