Hepatitis C virus: virology and life cycle 由 Chang Wook Kim, Kyong-Mi Chang

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72 Establishing a histologically defined NAFLD cohort in the Million Veteran Program for further genetic analyses 由 Samiran Mukherjee, Marijana Vujkovic, Kyong-Mi Chang

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Effects of metabolic traits, lifestyle factors, and pharmacological interventions on liver fat: mendelian randomisation study 由 Dipender Gill, Jie Chen, Susanna C Larsson, Xue Li, Shuai Yuan, Kyong-Mi Chang, Marijana Vujkovic

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Predicting short-term interruptions of antiretroviral therapy from summary adherence data: Development and test of a probability model. 由 Rebecca Arden Harris, Jessica E Haberer, Nicholas Musinguzi, Kyong-Mi Chang, Clyde B Schechter, Chyke A Doubeni, Robert Gross

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Synergistic reversal of intrahepatic HCV-specific CD8 T cell exhaustion by combined PD-1/CTLA-4 blockade. 由 Nobuhiro Nakamoto, Hyosun Cho, Abraham Shaked, Kim Olthoff, Mary E Valiga, Mary Kaminski, Emma Gostick, David A Price, Gordon J Freeman, E John Wherry, Kyong-Mi Chang

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Multi-trait association studies discover pleiotropic loci between Alzheimer’s disease and cardiometabolic traits 由 William P. Bone, Katherine M. Siewert, Anupama Jha, Derek Klarin, Scott M. Damrauer, The VA Million Veteran Program, Kyong-Mi Chang, Philip S. Tsao, Themistocles L. Assimes, Marylyn D. Ritchie, Benjamin F. Voight

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Genetic Evidence for Repurposing of GLP1R (Glucagon‐Like Peptide‐1 Receptor) Agonists to Prevent Heart Failure 由 Iyas Daghlas, Ville Karhunen, Devleena Ray, Verena Zuber, Stephen Burgess, Philip S. Tsao, Julie A. Lynch, Kyung Min Lee, Benjamin F. Voight, Kyong‐Mi Chang, Emma H. Baker, Scott M. Damrauer, Joanna M. M. Howson, Marijana Vujkovic, Dipender Gill

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259 Proton pump inhibitor use is not significantly associated with severe COVID-19 related outcomes after extensive covariate adjustment 由 Shailja C. Shah, Alese E. Halvorson, Brandon McBay, Chad Dorn, Otis Wilson, Jason Denton, Sony Tuteja, Kyong-Mi Chang, Kelly Cho, Richard L. Hauger, Ayako Suzuki, Christine M. Hunt, Edward Siew, Michael E. Matheny, Adriana Hung, Robert A. Greevy, Christianne L. Roumie

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A randomized, double-blind, placebo-controlled assessment of BMS-936558, a fully human monoclonal antibody to programmed death-1 (PD-1), in patients with chronic hepatitis C virus... 由 David Gardiner, Jay Lalezari, Eric Lawitz, Michael DiMicco, Rheem Ghalib, K Rajender Reddy, Kyong-Mi Chang, Mark Sulkowski, Steven O' Marro, Jeffrey Anderson, Bing He, Vikram Kansra, Fiona McPhee, Megan Wind-Rotolo, Dennis Grasela, Mark Selby, Alan J Korman, Israel Lowy

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Large-scale identification of undiagnosed hepatic steatosis using natural language processingResearch in context 由 Carolin V. Schneider, Tang Li, David Zhang, Anya I. Mezina, Puru Rattan, Helen Huang, Kate Townsend Creasy, Eleonora Scorletti, Inuk Zandvakili, Marijana Vujkovic, Leonida Hehl, Jacob Fiksel, Joseph Park, Kirk Wangensteen, Marjorie Risman, Kyong-Mi Chang, Marina Serper, Rotonya M. Carr, Kai Markus Schneider, Jinbo Chen, Daniel J. Rader

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Pharmacogenetic variants and risk of remdesivir‐associated liver enzyme elevations in Million Veteran Program participants hospitalized with COVID‐19 由 Sony Tuteja, Zhihong Yu, Otis Wilson, Hua‐Chang Chen, Frank Wendt, Cecilia P. Chung, Shailja C. Shah, Christine M. Hunt, Ayako Suzuki, Catherine Chanfreau, Bryan R. Gorman, Jacob Joseph, Shiuh‐Wen Luoh, Valerio Napolioni, Cassianne Robinson‐Cohen, Ran Tao, Jin Zhou, Kyong‐Mi Chang, Adriana M. Hung, the VA Million Veteran Program COVID‐19 Science Initiative

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Association of the transthyretin variant V122I with polyneuropathy among individuals of African ancestry 由 Margaret M. Parker, Scott M. Damrauer, Catherine Tcheandjieu, David Erbe, Emre Aldinc, Philip N. Hawkins, Julian D. Gillmore, Leland E. Hull, Julie A. Lynch, Jacob Joseph, Simina Ticau, Alexander O. Flynn-Carroll, Aimee M. Deaton, Lucas D. Ward, Themistocles L. Assimes, Philip S. Tsao, Kyong-Mi Chang, Daniel J. Rader, Kevin Fitzgerald, Akshay K. Vaishnaw, Gregory Hinkle, Paul Nioi

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Genome-wide and phenome-wide analysis of ideal cardiovascular health in the VA Million Veteran Program. 由 Rose D L Huang, Xuan-Mai T Nguyen, Gina M Peloso, Mark Trinder, Daniel C Posner, Krishna G Aragam, Yuk-Lam Ho, Julie A Lynch, Scott M Damrauer, Kyong-Mi Chang, Philip S Tsao, Pradeep Natarajan, Themistocles Assimes, J Michael Gaziano, Luc Djousse, Kelly Cho, Peter W F Wilson, Jennifer E Huffman, Christopher J O'Donnell, Veterans Affairs’ Million Veteran Program

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Genome-wide and phenome-wide analysis of ideal cardiovascular health in the VA Million Veteran Program 由 Rose D. L. Huang, Xuan-Mai T. Nguyen, Gina M. Peloso, Mark Trinder, Daniel C. Posner, Krishna G. Aragam, Yuk-Lam Ho, Julie A. Lynch, Scott M. Damrauer, Kyong-Mi Chang, Philip S. Tsao, Pradeep Natarajan, Themistocles Assimes, J. Michael Gaziano, Luc Djousse, Kelly Cho, Peter W. F. Wilson, Jennifer E. Huffman, Christopher J. O’Donnell, on behalf of the Veterans Affairs’ Million Veteran Program

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A missense variant in human perilipin 2 (PLIN2 Ser251Pro) reduces hepatic steatosis in mice 由 Eleonora Scorletti, Yedidya Saiman, Sookyoung Jeon, Carolin V. Schneider, Delfin G. Buyco, Chelsea Lin, Blanca E. Himes, Clementina A. Mesaros, Marijana Vujkovic, Kate Townsend Creasy, Emma E. Furth, Jeffrey T. Billheimer, Nicholas J. Hand, David E. Kaplan, Kyong-Mi Chang, Philip S. Tsao, Julie A. Lynch, Joseph L. Dempsey, Julia Harkin, Susovon Bayen, Donna Conlon, Marie Guerraty, Michael C. Phillips, Daniel J. Rader, Rotonya M. Carr

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Highly multiplexed 2-dimensional imaging mass cytometry analysis of HBV-infected liver 由 Daniel Traum, Yue J. Wang, Kathleen B. Schwarz, Jonathan Schug, David K.H. Wong, Harry L.A. Janssen, Norah A. Terrault, Mandana Khalili, Abdus S. Wahed, Karen F. Murray, Phillip Rosenthal, Simon C. Ling, Norberto Rodriguez-Baez, Richard K. Sterling, Daryl T.Y. Lau, Timothy M. Block, Michael D. Feldman, Elizabeth E. Furth, William M. Lee, David E. Kleiner, Anna S. Lok, Klaus H. Kaestner, Kyong-Mi Chang

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A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program 由 Sridharan Raghavan, Jie Huang, Catherine Tcheandjieu, Jennifer E. Huffman, Elizabeth Litkowski, Chang Liu, Yuk-Lam A. Ho, Haley Hunter-Zinck, Hongyu Zhao, Eirini Marouli, Kari E. North, the VA Million Veteran Program, Ethan Lange, Leslie A. Lange, Benjamin F. Voight, J. Michael Gaziano, Saiju Pyarajan, Elizabeth R. Hauser, Philip S. Tsao, Peter W. F. Wilson, Kyong-Mi Chang, Kelly Cho, Christopher J. O’Donnell, Yan V. Sun, Themistocles L. Assimes

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A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program. 由 Sridharan Raghavan, Jie Huang, Catherine Tcheandjieu, Jennifer E Huffman, Elizabeth Litkowski, Chang Liu, Yuk-Lam A Ho, Haley Hunter-Zinck, Hongyu Zhao, Eirini Marouli, Kari E North, VA Million Veteran Program, Ethan Lange, Leslie A Lange, Benjamin F Voight, J Michael Gaziano, Saiju Pyarajan, Elizabeth R Hauser, Philip S Tsao, Peter W F Wilson, Kyong-Mi Chang, Kelly Cho, Christopher J O'Donnell, Yan V Sun, Themistocles L Assimes

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Phenome-wide association of 1809 phenotypes and COVID-19 disease progression in the Veterans Health Administration Million Veteran Program. 由 Rebecca J Song, Yuk-Lam Ho, Petra Schubert, Yojin Park, Daniel Posner, Emily M Lord, Lauren Costa, Hanna Gerlovin, Katherine E Kurgansky, Tori Anglin-Foote, Scott DuVall, Jennifer E Huffman, Saiju Pyarajan, Jean C Beckham, Kyong-Mi Chang, Katherine P Liao, Luc Djousse, David R Gagnon, Stacey B Whitbourne, Rachel Ramoni, Sumitra Muralidhar, Philip S Tsao, Christopher J O'Donnell, John Michael Gaziano, Juan P Casas, Kelly Cho, VA Million Veteran Program COVID-19 Science Initiative

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Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program. 由 Marina Serper, Marijana Vujkovic, David E Kaplan, Rotonya M Carr, Kyung Min Lee, Qing Shao, Donald R Miller, Peter D Reaven, Lawrence S Phillips, Christopher J O'Donnell, James B Meigs, Peter W F Wilson, Rachel Vickers-Smith, Henry R Kranzler, Amy C Justice, John M Gaziano, Sumitra Muralidhar, Saiju Pyarajan, Scott L DuVall, Themistocles L Assimes, Jennifer S Lee, Philip S Tsao, Daniel J Rader, Scott M Damrauer, Julie A Lynch, Danish Saleheen, Benjamin F Voight, Kyong-Mi Chang, VA Million Veteran Program

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