The Origin and Evolution of Release Factors: Implications for Translation Termination, Ribosome Rescue, and Quality Control Pathways by A. Maxwell Burroughs, L Aravind

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Inferring joint sequence-structural determinants of protein functional specificity by Andrew F Neuwald, L Aravind, Stephen F Altschul

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Novel Immunoglobulin Domain Proteins Provide Insights into Evolution and Pathogenesis of SARS-CoV-2-Related Viruses by Yongjun Tan, Theresa Schneider, Matthew Leong, L. Aravind, Dapeng Zhang

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Unexpected Evolution of Lesion-Recognition Modules in Eukaryotic NER and Kinetoplast DNA Dynamics Proteins from Bacterial Mobile Elements by Arunkumar Krishnan, A. Maxwell Burroughs, Lakshminarayan M. Iyer, L. Aravind

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Apprehending the NAD⁺–ADPr-Dependent Systems in the Virus World by Lakshminarayan M. Iyer, A. Maxwell Burroughs, Vivek Anantharaman, L. Aravind

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Highly regulated, diversifying NTP-dependent biological conflict systems with implications for the emergence of multicellularity by Gurmeet Kaur, A Maxwell Burroughs, Lakshminarayan M Iyer, L Aravind

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Bacterial death and TRADD-N domains help define novel apoptosis and immunity mechanisms shared by prokaryotes and metazoans by Gurmeet Kaur, Lakshminarayan M Iyer, A Maxwell Burroughs, L Aravind

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Jumbo Phages: A Comparative Genomic Overview of Core Functions and Adaptions for Biological Conflicts by Lakshminarayan M. Iyer, Vivek Anantharaman, Arunkumar Krishnan, A. Maxwell Burroughs, L. Aravind

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Babesia microti: Pathogen Genomics, Genetic Variability, Immunodominant Antigens, and Pathogenesis by Ankit Puri, Surabhi Bajpai, Scott Meredith, L. Aravind, Peter J. Krause, Sanjai Kumar

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Antimicrobial Peptides, Polymorphic Toxins, and Self-Nonself Recognition Systems in Archaea: an Untapped Armory for Intermicrobial Conflicts by Kira S. Makarova, Yuri I. Wolf, Svetlana Karamycheva, Dapeng Zhang, L. Aravind, Eugene V. Koonin

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Functional Innovation in the Evolution of the Calcium-Dependent System of the Eukaryotic Endoplasmic Reticulum by Daniel E. Schäffer, Daniel E. Schäffer, Lakshminarayan M. Iyer, A. Maxwell Burroughs, L. Aravind

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Erasure of Tet-Oxidized 5-Methylcytosine by a SRAP Nuclease by Soo-Mi Kweon, Bing Zhu, Yibu Chen, L. Aravind, Shuang-Yong Xu, Douglas E. Feldman

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Deciphering the Role of a SLOG Superfamily Protein YpsA in Gram-Positive Bacteria by Robert S. Brzozowski, Mirella Huber, A. Maxwell Burroughs, Gianni Graham, Merryck Walker, Sameeksha S. Alva, L. Aravind, Prahathees J. Eswara

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"RETRACTED ARTICLE: Vibrio parahaemolyticus RhsP represents a widespread group of pro-effectors for type VI secretion systems by Nan Jiang, Le Tang, Ruiqiang Xie, Zhi Li, Brianne Burkinshaw, Xiaoye Liang, Dylan Sosa, L. Aravind, Tao Dong, Dapeng Zhang, Jun Zheng

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Retraction Note: Vibrio parahaemolyticus RhsP represents a widespread group of pro-effectors for type VI secretion systems by Nan Jiang, Le Tang, Ruiqiang Xie, Zhi Li, Brianne Burkinshaw, Xiaoye Liang, Dylan Sosa, L. Aravind, Tao Dong, Dapeng Zhang, Jun Zheng

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Evolution and multiple roles of the Pancrustacea specific transcription factor zelda in insects. by Lupis Ribeiro, Vitória Tobias-Santos, Daniele Santos, Felipe Antunes, Geórgia Feltran, Jackson de Souza Menezes, L Aravind, Thiago M Venancio, Rodrigo Nunes da Fonseca

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Mechanism and evolutionary origins of alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10 by Pratik Rajendra Patil, A. Maxwell Burroughs, Mohit Misra, Federico Cerullo, Carlos Costas Insua, Hao-Chih Hung, Ivan Dikic, L. Aravind, Claudio A.P. Joazeiro

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<named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Rv0991c Is a Redox-Regulated Molecular Chaperone by Samuel H. Becker, Kathrin Ulrich, Avantika Dhabaria, Beatrix Ueberheide, William Beavers, Eric P. Skaar, Lakshminarayan M. Iyer, L. Aravind, Ursula Jakob, K. Heran Darwin

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MORC2 Signaling Integrates Phosphorylation-Dependent, ATPase-Coupled Chromatin Remodeling during the DNA Damage Response by Da-Qiang Li, Sujit S. Nair, Kazufumi Ohshiro, Anupam Kumar, Vasudha S. Nair, Suresh B. Pakala, Sirigiri Divijendra Natha Reddy, Rajendra P. Gajula, Jeyanthy Eswaran, L. Aravind, Rakesh Kumar

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VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities by Taylor M. Gerson, Audrey M. Ott, Monika M. A. Karney, Jillian N. Socea, Daren R. Ginete, Lakshminarayan M. Iyer, L. Aravind, Ronald K. Gary, Helen J. Wing

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