Interaction of background genetic risk, psychotropic medications, and primary angle closure glaucoma in the UK Biobank. by Sayuri Sekimitsu, Jiali Wang, Tobias Elze, Ayellet V Segrè, Janey L Wiggs, Nazlee Zebardast

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Association of Matrix Metalloproteinase-9 (MMP9) Variants with Primary Angle Closure and Primary Angle Closure Glaucoma. by Xueli Chen, Yuhong Chen, Janey L Wiggs, Louis R Pasquale, Xinghuai Sun, Bao Jian Fan

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Bupropion use and risk of open-angle glaucoma among enrollees in a large U.S. managed care network. by Joshua D Stein, Nidhi Talwar, Jae H Kang, Olivia I Okereke, Janey L Wiggs, Louis R Pasquale

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The use of MElatonin in children with Neurodevelopmental Disorders and impaired Sleep: a randomised, double-blind, placebo-controlled, parallel study (MENDS) by RE Appleton, AP Jones, C Gamble, PR Williamson, L Wiggs, P Montgomery, A Sutcliffe, C Barker, P Gringras

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Mechanosensitive ion channel gene survey suggests potential roles in primary open angle glaucoma by Wendy W. Liu, Tyler G. Kinzy, Jessica N. Cooke Bailey, Zihe Xu, Pirro Hysi, Janey L. Wiggs, NEIGHBORHOOD Consortium

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Association between Diabetes and Exfoliation Syndrome by Megan Yu, BS, Hannah H. Hwang, BS, Janey L. Wiggs, MD, PhD, Louis R. Pasquale, MD, Jae H. Kang, ScD

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POU6F2, a risk factor for glaucoma, myopia and dyslexia, labels specific populations of retinal ganglion cells by Fangyu Lin, Ying Li, Jiaxing Wang, Sandra Jardines, Rebecca King, Micah A. Chrenek, Janey L. Wiggs, Jeffrey H. Boatright, Eldon E. Geisert

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Muir-Torre Syndrome: The Importance of a Detailed Family History by Christopher K.H. Burris, Maria E. Rodriguez, Meisha L. Raven, Devasis N. Reddy, Yaohui G. Xu, Janey L. Wiggs, Heather D. Potter, Daniel M. Albert

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Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility by Sumana R. Chintalapudi, Doaa Maria, Xiang Di Wang, Jessica N. Cooke Bailey, NEIGHBORHOOD consortium, International Glaucoma Genetics consortium, Pirro G. Hysi, Janey L. Wiggs, Robert W. Williams, Monica M. Jablonski

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Thrombospondin 1 missense alleles induce extracellular matrix protein aggregation and TM dysfunction in congenital glaucoma by Haojie Fu, Owen M. Siggs, Lachlan S.W. Knight, Sandra E. Staffieri, Jonathan B. Ruddle, Amy E. Birsner, Edward Ryan Collantes, Jamie E. Craig, Janey L. Wiggs, Robert J. D’Amato

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Habitual coffee consumption and genetic predisposition to obesity: gene-diet interaction analyses in three US prospective studies by Tiange Wang, Tao Huang, Jae H. Kang, Yan Zheng, Majken K. Jensen, Janey L. Wiggs, Louis R. Pasquale, Charles S. Fuchs, Hannia Campos, Eric B. Rimm, Walter C. Willett, Frank B. Hu, Lu Qi

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The p53 codon 72 PRO/PRO genotype may be associated with initial central visual field defects in caucasians with primary open angle glaucoma. by Janey L Wiggs, Alex W Hewitt, Bao Jian Fan, Dan Yi Wang, Dayse R Figueiredo Sena, Colm O'Brien, Anthony Realini, Jamie E Craig, David P Dimasi, David A Mackey, Jonathan L Haines, Louis R Pasquale

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Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank by Oana A. Zeleznik, Jae H. Kang, Jessica Lasky-Su, A. Heather Eliassen, Lisa Frueh, Clary B. Clish, Bernard A. Rosner, Tobias Elze, Pirro Hysi, Anthony Khawaja, Janey L. Wiggs, Louis R. Pasquale, UK Biobank Eye and Vision Consortium

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Genome-wide linkage scan for primary open angle glaucoma: influences of ancestry and age at diagnosis. by Kristy R Crooks, R Rand Allingham, Xuejun Qin, Yutao Liu, Jason R Gibson, Cecilia Santiago-Turla, Karen R Larocque-Abramson, Elizabeth Del Bono, Pratap Challa, Leon W Herndon, Stephen Akafo, Janey L Wiggs, Silke Schmidt, Michael A Hauser

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Machine Learning on Prediagnostic Metabolite Data Identifies Etiologic Endotypes of Exfoliation Glaucoma in United States Health Professionals by Akiko Hanyuda, MD, MPH, Oana A. Zeleznik, PhD, Yoshihiko Raita, MD, MPH, Kazuno Negishi, MD, PhD, Louis R. Pasquale, MD, Jessica Lasky-Su, ScD, Janey L. Wiggs, MD, PhD, Jae H. Kang, ScD

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Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma. by Rebecca King, Felix L Struebing, Ying Li, Jiaxing Wang, Allison Ashley Koch, Jessica N Cooke Bailey, Puya Gharahkhani, International Glaucoma Genetics Consortium, NEIGHBORHOOD Consortium, Stuart MacGregor, R Rand Allingham, Michael A Hauser, Janey L Wiggs, Eldon E Geisert

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Disentangling the genetic overlap and causal relationships between primary open-angle glaucoma, brain morphology and four major neurodegenerative disordersResearch in context by Santiago Diaz-Torres, Weixiong He, Jackson Thorp, Sahba Seddighi, Sean Mullany, Christopher J. Hammond, Pirro G. Hysi, Louis R. Pasquale, Anthony P. Khawaja, Alex W. Hewitt, Jamie E. Craig, David A. Mackey, Janey L. Wiggs, Cornelia van Duijn, Michelle K. Lupton, Jue-Sheng Ong, Stuart MacGregor, Puya Gharahkhani

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Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium. by Shefali Setia Verma, Jessica N Cooke Bailey, Anastasia Lucas, Yuki Bradford, James G Linneman, Michael A Hauser, Louis R Pasquale, Peggy L Peissig, Murray H Brilliant, Catherine A McCarty, Jonathan L Haines, Janey L Wiggs, Tamara R Vrabec, Gerard Tromp, Marylyn D Ritchie, eMERGE Network, NEIGHBOR Consortium

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Genome-wide meta-analysis identifies 22 loci for normal tension glaucoma with significant overlap with high tension glaucoma by Santiago Diaz-Torres, Weixiong He, Regina Yu, IGGC International Glaucoma Genetics Consortium, Anthony P. Khawaja, Christopher J. Hammond, Pirro G. Hysi, Louis R. Pasquale, Yeda Wu, Michiaki Kubo, Masato Akiyama, Tin Aung, Ching-Yu Cheng, Chiea Chuen Khor, Peter Kraft, Jae H. Kang, Alex W. Hewitt, David A. Mackey, Jamie E. Craig, Janey L. Wiggs, Jue-Sheng Ong, Stuart MacGregor, Puya Gharahkhani

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Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma by Andrew R. Hamel, Wenjun Yan, John M. Rouhana, Aboozar Monovarfeshani, Xinyi Jiang, Puja A. Mehta, Jayshree Advani, Yuyang Luo, Qingnan Liang, Skanda Rajasundaram, Arushi Shrivastava, Katherine Duchinski, Sreekar Mantena, Jiali Wang, Tavé van Zyl, Louis R. Pasquale, Anand Swaroop, Puya Gharahkhani, Anthony P. Khawaja, Stuart MacGregor, International Glaucoma Genetics Consortium (IGGC), Rui Chen, Veronique Vitart, Joshua R. Sanes, Janey L. Wiggs, Ayellet V. Segrè

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