Editorial: Community series in towards precision medicine for immune-mediated disorders: advances in using big data and artificial intelligence to understand heterogeneity in infla... gan Xu-jie Zhou, Xu-jie Zhou, Xu-jie Zhou, Xu-jie Zhou, Xu-jie Zhou, Yasmina Laouar, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi

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Skin-Expressing lncRNAs in Inflammatory Responses gan Alanna Shefler, Matthew T. Patrick, Rachael Wasikowski, Jiahan Chen, Mrinal K. Sarkar, Johann E. Gudjonsson, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi

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A partitioned 88-loci psoriasis genetic risk score reveals HLA and non-HLA contributions to clinical phenotypes in a Newfoundland psoriasis cohort gan Audrey Bui, Audrey Bui, Sugandh Kumar, Jared Liu, Faye Orcales, Susanne Gulliver, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi, Wayne Gulliver, Wayne Gulliver, Wilson Liao

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Large-scale epidemiological analysis of common skin diseases to identify shared and unique comorbidities and demographic factors gan Qinmengge Li, Matthew T. Patrick, Sutharzan Sreeskandarajan, Jian Kang, J. Michelle Kahlenberg, J. Michelle Kahlenberg, Johann E. Gudjonsson, Zhi He, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi

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Roles Played by Stress-Induced Pathways in Driving Ethnic Heterogeneity for Inflammatory Skin Diseases gan Taylor A. Jamerson, Qinmengge Li, Sutharzan Sreeskandarajan, Irina V. Budunova, Irina V. Budunova, Zhi He, Jian Kang, Johann E. Gudjonsson, Matthew T. Patrick, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi

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The Promise of Genomic Studies on Human Diseases: From Basic Science to Clinical Application gan Lam C. Tsoi, Bethany Wolf, Y. Ann Chen

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Machine learning workflow to enhance predictions of Adverse Drug Reactions (ADRs) through drug-gene interactions: application to drugs for cutaneous diseases gan Kalpana Raja, Matthew Patrick, James T. Elder, Lam C. Tsoi

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Loss of interleukin-1 beta is not protective in the lupus-prone NZM2328 mouse model gan Shannon N. Loftus, Shannon N. Loftus, Jianhua Liu, Celine C. Berthier, Johann E. Gudjonsson, Mehrnaz Gharaee-Kermani, Mehrnaz Gharaee-Kermani, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi, J. Michelle Kahlenberg, J. Michelle Kahlenberg

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FABIO: TWAS fine-mapping to prioritize causal genes for binary traits. gan Haihan Zhang, Kevin He, Zheng Li, Lam C Tsoi, Xiang Zhou

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A Review of Recent Advancement in Integrating Omics Data with Literature Mining towards Biomedical Discoveries gan Kalpana Raja, Matthew Patrick, Yilin Gao, Desmond Madu, Yuyang Yang, Lam C. Tsoi

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B Cell Signatures Distinguish Cutaneous Lupus Erythematosus Subtypes and the Presence of Systemic Disease Activity gan Lisa Abernathy-Close, Stephanie Lazar, Jasmine Stannard, Jasmine Stannard, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi, Sean Eddy, Syed M. Rizvi, Christine M. Yee, Emily M. Myers, Rajaie Namas, Lori Lowe, Lori Lowe, Tamra J. Reed, Fei Wen, Johann E. Gudjonsson, J. Michelle Kahlenberg, Celine C. Berthier

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Enhanced rare disease mapping for phenome-wide genetic association in the UK Biobank gan Matthew T. Patrick, Redina Bardhi, Wei Zhou, James T. Elder, Johann E. Gudjonsson, Lam C. Tsoi

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Prognostic value of intratumoral lymphocyte-to-monocyte ratio and M0 macrophage enrichment in tumor immune microenvironment of melanoma gan Neil K Jairath, Mark W Farha, Ruple Jairath, Paul W Harms, Lam C Tsoi, Trilokraj Tejasvi

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4421 Exposure to topical antimicrobials reduces inflammatory gene expression in keratinocytes gan Sirisha Sirobhushanam, Allison C Billi, Celine C Berthier, Lam C Tsoi, Johann E Gudjonsson, J Michelle Kahlenberg

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Shared genetic risk factors and causal association between psoriasis and coronary artery disease gan Matthew T. Patrick, Qinmengge Li, Rachael Wasikowski, Nehal Mehta, Johann E. Gudjonsson, James T. Elder, Xiang Zhou, Lam C. Tsoi

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Integrative Approach to Reveal Cell Type Specificity and Gene Candidates for Psoriatic Arthritis Outside the MHC gan Matthew T. Patrick, Philip E. Stuart, Kalpana Raja, Kalpana Raja, Sunyi Chi, Sunyi Chi, Zhi He, John J. Voorhees, Trilokraj Tejasvi, Trilokraj Tejasvi, Johann E. Gudjonsson, J. Michelle Kahlenberg, Vinod Chandran, Vinod Chandran, Vinod Chandran, Vinod Chandran, Vinod Chandran, Proton Rahman, Dafna D. Gladman, Dafna D. Gladman, Dafna D. Gladman, Rajan P. Nair, James T. Elder, James T. Elder, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi

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2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T Cells gan Stephanie T. Le, Alexander A. Merleev, Guillaume Luxardi, Michiko Shimoda, Iannis E. Adamopoulos, Lam C. Tsoi, Lam C. Tsoi, Jenny Z. Wang, Jenny Z. Wang, Claire Alexanian, Claire Alexanian, Siba P. Raychaudhuri, Siba P. Raychaudhuri, Samuel T. Hwang, Johann Gudjonsson, Alina I. Marusina, Emanual Maverakis

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tauFisher predicts circadian time from a single sample of bulk and single-cell pseudobulk transcriptomic data gan Junyan Duan, Michelle N. Ngo, Satya Swaroop Karri, Lam C. Tsoi, Johann E. Gudjonsson, Babak Shahbaba, John Lowengrub, Bogi Andersen

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Significance of stress keratin expression in normal and diseased epithelia gan Erez Cohen, Craig N. Johnson, Rachael Wasikowski, Allison C. Billi, Lam C. Tsoi, J. Michelle Kahlenberg, Johann E. Gudjonsson, Pierre A. Coulombe

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Predictors of large cell transformation in patients with Sezary Syndrome-A retrospective analysis. gan Neil K Jairath, Redina Bardhi, John S Runge, Ramona Bledea, Ruple Jairath, Yang Wang, Matthew Patrick, Ryan A Wilcox, Alexandra C Hristov, Lam C Tsoi, Trilokraj Tejasvi

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