Editorial: Community series in towards precision medicine for immune-mediated disorders: advances in using big data and artificial intelligence to understand heterogeneity in infla... by Xu-jie Zhou, Xu-jie Zhou, Xu-jie Zhou, Xu-jie Zhou, Xu-jie Zhou, Yasmina Laouar, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi

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A partitioned 88-loci psoriasis genetic risk score reveals HLA and non-HLA contributions to clinical phenotypes in a Newfoundland psoriasis cohort by Audrey Bui, Audrey Bui, Sugandh Kumar, Jared Liu, Faye Orcales, Susanne Gulliver, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi, Wayne Gulliver, Wayne Gulliver, Wilson Liao

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Large-scale epidemiological analysis of common skin diseases to identify shared and unique comorbidities and demographic factors by Qinmengge Li, Matthew T. Patrick, Sutharzan Sreeskandarajan, Jian Kang, J. Michelle Kahlenberg, J. Michelle Kahlenberg, Johann E. Gudjonsson, Zhi He, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi

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The Promise of Genomic Studies on Human Diseases: From Basic Science to Clinical Application by Lam C. Tsoi, Bethany Wolf, Y. Ann Chen

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Loss of interleukin-1 beta is not protective in the lupus-prone NZM2328 mouse model by Shannon N. Loftus, Shannon N. Loftus, Jianhua Liu, Celine C. Berthier, Johann E. Gudjonsson, Mehrnaz Gharaee-Kermani, Mehrnaz Gharaee-Kermani, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi, J. Michelle Kahlenberg, J. Michelle Kahlenberg

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FABIO: TWAS fine-mapping to prioritize causal genes for binary traits. by Haihan Zhang, Kevin He, Zheng Li, Lam C Tsoi, Xiang Zhou

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A Review of Recent Advancement in Integrating Omics Data with Literature Mining towards Biomedical Discoveries by Kalpana Raja, Matthew Patrick, Yilin Gao, Desmond Madu, Yuyang Yang, Lam C. Tsoi

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Prognostic value of intratumoral lymphocyte-to-monocyte ratio and M0 macrophage enrichment in tumor immune microenvironment of melanoma by Neil K Jairath, Mark W Farha, Ruple Jairath, Paul W Harms, Lam C Tsoi, Trilokraj Tejasvi

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4421 Exposure to topical antimicrobials reduces inflammatory gene expression in keratinocytes by Sirisha Sirobhushanam, Allison C Billi, Celine C Berthier, Lam C Tsoi, Johann E Gudjonsson, J Michelle Kahlenberg

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tauFisher predicts circadian time from a single sample of bulk and single-cell pseudobulk transcriptomic data by Junyan Duan, Michelle N. Ngo, Satya Swaroop Karri, Lam C. Tsoi, Johann E. Gudjonsson, Babak Shahbaba, John Lowengrub, Bogi Andersen

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Significance of stress keratin expression in normal and diseased epithelia by Erez Cohen, Craig N. Johnson, Rachael Wasikowski, Allison C. Billi, Lam C. Tsoi, J. Michelle Kahlenberg, Johann E. Gudjonsson, Pierre A. Coulombe

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Predictors of large cell transformation in patients with Sezary Syndrome-A retrospective analysis. by Neil K Jairath, Redina Bardhi, John S Runge, Ramona Bledea, Ruple Jairath, Yang Wang, Matthew Patrick, Ryan A Wilcox, Alexandra C Hristov, Lam C Tsoi, Trilokraj Tejasvi

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Comparative analyses of Netherton syndrome patients and Spink5 conditional knock-out mice uncover disease-relevant pathways by Evgeniya Petrova, Jesús María López-Gay, Matthias Fahrner, Florent Leturcq, Jean-Pierre de Villartay, Claire Barbieux, Patrick Gonschorek, Lam C. Tsoi, Johann E. Gudjonsson, Oliver Schilling, Alain Hovnanian

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Serial KinderMiner (SKiM) discovers and annotates biomedical knowledge using co-occurrence and transformer models by Robert J. Millikin, Kalpana Raja, John Steill, Cannon Lock, Xuancheng Tu, Ian Ross, Lam C. Tsoi, Finn Kuusisto, Zijian Ni, Miron Livny, Brian Bockelman, James Thomson, Ron Stewart

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Tofacitinib blocks IFN-regulated biomarker genes in skin fibroblasts and keratinocytes in a systemic sclerosis trial by Dinesh Khanna, Cristina Padilla, Lam C. Tsoi, Vivek Nagaraja, Puja P. Khanna, Tracy Tabib, J. Michelle Kahlenberg, Amber Young, Suiyuan Huang, Johann E. Gudjonsson, David A. Fox, Robert Lafyatis

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HERC6 regulates STING activity in a sex-biased manner through modulation of LATS2/VGLL3 Hippo signaling by Ranjitha Uppala, Mrinal K. Sarkar, Kelly Z. Young, Feiyang Ma, Pritika Vemulapalli, Rachael Wasikowski, Olesya Plazyo, William R. Swindell, Emanual Maverakis, Mehrnaz Gharaee-Kermani, Allison C. Billi, Lam C. Tsoi, J. Michelle Kahlenberg, Johann E. Gudjonsson

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Transcriptional profiling of rare acantholytic disorders suggests common mechanisms of pathogenesis by Quinn R. Roth-Carter, Hope E. Burks, Ziyou Ren, Jennifer L. Koetsier, Lam C. Tsoi, Paul W. Harms, Xianying Xing, Joseph Kirma, Robert M. Harmon, Lisa M. Godsel, Abbey L. Perl, Johann E. Gudjonsson, Kathleen J. Green

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Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus by Chachrit Khunsriraksakul, Qinmengge Li, Havell Markus, Matthew T. Patrick, Renan Sauteraud, Daniel McGuire, Xingyan Wang, Chen Wang, Lida Wang, Siyuan Chen, Ganesh Shenoy, Bingshan Li, Xue Zhong, Nancy J. Olsen, Laura Carrel, Lam C. Tsoi, Bibo Jiang, Dajiang J. Liu

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Keratinocytes sense and eliminate CRISPR DNA through STING/IFN-κ activation and APOBEC3G induction by Mrinal K. Sarkar, Ranjitha Uppala, Chang Zeng, Allison C. Billi, Lam C. Tsoi, Austin Kidder, Xianying Xing, Bethany E. Perez White, Shuai Shao, Olesya Plazyo, Sirisha Sirobhushanam, Enze Xing, Yanyun Jiang, Katherine A. Gallagher, John J. Voorhees, J. Michelle Kahlenberg, Johann E. Gudjonsson

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Vitamin D3 and deconvoluting a rash by Madison K. Ernst, Spencer T. Evans, Jose-Marc Techner, Robert M. Rothbaum, Luisa F. Christensen, Ummiye Venus Onay, Dauren Biyashev, Michael M. Demczuk, Cuong V. Nguyen, Kord S. Honda, Thomas S. McCormick, Lam C. Tsoi, Johann E. Gudjonsson, Kevin D. Cooper, Kurt Q. Lu

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