A Central Role for mTOR in Lipid Homeostasis by Lamming, Dudley W., Sabatini, David M., Lamming, Dudley W., Sabatini, David

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7.342 The Biology of Aging: Age-Related Diseases and Interventions, Fall 2011 by Lamming, Dudley W., Bell, Eric L.

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A Radical Role for TOR in Longevity by Lamming, Dudley W., Sabatini, David M., Sabatini, David

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TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO by Robida-Stubbs, Stacey, Glover-Cutter, Kira, Lamming, Dudley W., Mizunuma, Masaki, Narasimhan, Sri Devi, Neumann-Haefelin, Elke, Sabatini, David M., Blackwell, T. Keith, Lamming, Dudley W., Sabatini, David

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Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2 by Ye, Lan, Varamini, Behzad, Baur, Joseph A., Sabatini, David, Lamming, Dudley W.

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Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive by Lamming, Dudley W., Ye, Lan, Astle, Clinton M., Baur, Joseph A., Harrison, David E., Sabatini, David

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The TSC-mTOR pathway regulates macrophage polarization by Byles, Vanessa, Covarrubias, Anthony J., Ben-Sahra, Issam, Lamming, Dudley W., Manning, Brendan D., Horng, Tiffany, Sabatini, David

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Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan by Lamming, Dudley W., Mihaylova, Maria M., Katajisto, Pekka, Baar, Emma L., Yilmaz, Omer, Hutchins, Amanda W., Gultekin, Yetis, Gaither, Rachel P., Sabatini, David M.

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Rapamycin Doses Sufficient to Extend Lifespan Do Not Compromise Muscle Mitochondrial Content or Endurance by Ye, Lan, Widlund, Anne L., Sims, Carrie A., Lamming, Dudley W., Guan, Yuxia, Davis, James G., Harrison, David E., Vang, Ole, Baur, Joseph A., Sabatini, David

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SYK kinase mediates brown fat differentiation and activation by Knoll, Marko, Winther, Sally, Natarajan, Anirudh, Yang, Huan, Jiang, Mengxi, Thiru, Prathapan, Shahsafaei, Aliakbar, Chavarria, Tony E., Lamming, Dudley W., Sun, Lei, Hansen, Jacob B., Lodish, Harvey F

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Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile by Mercken, Evi M., Crosby, Seth D., Lamming, Dudley W., JeBailey, Lellean, Krzysik-Walker, Susan, Villareal, Dennis T., Capri, Miriam, Franceschi, Claudio, Zhang, Yongqing, Becker, Kevin, de Cabo, Rafael, Fontana, Luigi, Sabatini, David

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Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity by Lamming, Dudley W., Ye, Lan, Katajisto, Pekka, Goncalves, Marcus D., Saitoh, Maki, Stevens, Deanna M., Davis, James G., Salmon, Adam B., Richardson, Arlan, Ahima, Rexford S., Guertin, David A., Baur, Joseph A., Sabatini, David

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The Adaptor Protein p66Shc Inhibits mTOR-Dependent Anabolic Metabolism by Lamming, Dudley W., Soliman, Mohamed A., Abdel Rahman, Anas M., Birsoy, Kivanc, Pawling, Judy, Frigolet, Maria E., Lu, Huogen, Fantus, I. George, Pasculescu, Adrian, Zheng, Yong, Dennis, James W., Pawson, Tony, Sabatini, David

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mTORC1 in the Paneth cell niche couples intestinal stem cell function to calorie intake by Katajisto, Pekka, Lamming, Dudley W., Gultekin, Yetis, Bauer-Rowe, Khristian E., Sengupta, Shomit, Birsoy, Kivanc, Dursun, Abdulmetin, Yilmaz, V. Onur, Selig, Martin, Nielson, G. Petur, Mino-Kenudson, Mari, Zuckerberg, Lawrence, Bahn, Atul K., Deshpande, Vikram, Yilmaz, Omer, Sabatini, David

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High-fat diet enhances stemness and tumorigenicity of intestinal progenitors by Saadatpour, Assieh, Hong, Sue-Jean, Pinello, Luca, Katz, Yarden, Lamming, Dudley W., Guo, Guoji, Bell, George W., Selig, Martin, Nielsen, G. Petur, Gupta, Nitin, Ferrone, Cristina R., Deshpande, Vikram, Yuan, Guo-Cheng, Orkin, Stuart H., Beyaz, Semir, Mana, Miyeko, Roper, Jatin, Kedrin, Dmitriy, Bauer-Rowe, Khristian E., Xifaras, Michael, Akkad, Adam, Arias, Erika, Shinagare, Shweta, Abu-Remaileh, Monther, Dogum, Rizkullah, Sabatini, David, Yilmaz, Omer, Mihaylova, Maria M.

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Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer by Strong, Randy, Miller, Richard A., Antebi, Adam, Astle, Clinton M., Bogue, Molly, Denzel, Martin S., Fernandez, Elizabeth, Flurkey, Kevin, Hamilton, Karyn L., Lamming, Dudley W., Javors, Martin A., de Magalhães, João Pedro, Martinez, Paul Anthony, McCord, Joe M., Miller, Benjamin F., Müller, Michael, Nelson, James F., Ndukum, Juliet, Rainger, G. Ed., Richardson, Arlan, Salmon, Adam B., Simpkins, James W., Steegenga, Wilma T., Nadon, Nancy L., Harrison, David E., Sabatini, David

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