Large-scale, family-based, candidate gene association study of type 2 diabetes mellitus and abdominal obesity nork Hirschhorn, J, Altshuler, D, Lindgren, C, Lane, C, Nemesh, J, Bolk, S, Sklar, P, Groop, L, Lander, E

Human genome sequence variation and the influence of gene history, mutation and recombination. nork Reich, D, Schaffner, S, Daly, M, McVean, G, Mullikin, J, Higgins, J, Richter, D, Lander, E, Altshuler, D

Association Study of Lipoprotein (a) Genetic Markers, Traditional Risk Factors and Coronary Heart Disease in HIV-1-infected Patients nork Lander eEgaña-Gorroño, Esteban eMartinez, Tuixent eEscribà, Marta eCalvo, Jose eGatell, Mireia eArnedo

Testu osoa

Detecting novel associations in large data sets. nork Reshef, D, Reshef, Y, Finucane, H, Grossman, SR, McVean, G, Turnbaugh, P, Lander, E, Mitzenmacher, M, Sabeti, P

Application of high-throughout SNP genotyping to complex endocrine diseases. nork Hirschorn, J, Altshuler, D, Sklar, P, Bolk, S, Lindblad, K, Lindgren, C, Lim, Y, Lane, C, Nemesh, J, Groop, L, Lander, E

Large-scale candidate gene association studies of type 2 diabetes. nork Hirschhom, J, Altshuler, D, Lindgren, C, Klannemark, M, Daly, M, Vohl, M, Nemesh, J, Lane, C, Bolk, S, Hudson, T, Groop, L, Lander, E

Linkage disequilibrium at PPARG and other genes assessed with dense sets of SNPs.. nork Hirschhorn, J, Altshuler, D, Daly, M, Lindgren, C, Burtt, N, Loomer, M, Villapakkam, A, Bolk, S, O'Donnell, C, Crews, J, Groop, L, Lander, E

A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. nork Miretti, M, Walsh, E, Ke, X, Delgado, M, Griffiths, M, Hunt, S, Morrison, J, Whittaker, P, Lander, E, Cardon, L, Bentley, DR, Rioux, J, Beck, S, Deloukas, P

Genomewide linkage analysis of stature in multiple populations reveals several regions with evidence of linkage to adult height. nork Hirschhorn, J, Lindgren, C, Daly, M, Kirby, A, Schaffner, S, Burtt, N, Altshuler, D, Parker, A, Rioux, J, Platko, J, Gaudet, D, Hudson, T, Groop, L, Lander, E

Deuterostome phylogeny reveals monophyletic chordates and the new phylum Xenoturbellida. nork Bourlat, S, Juliusdottir, T, Lowe, C, Freeman, R, Aronowicz, J, Kirschner, M, Lander, E, Thorndyke, M, Nakano, H, Kohn, AB, Heyland, A, Moroz, L, Copley, R, Telford, M

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. nork Altshuler, D, Hirschhorn, J, Klannemark, M, Lindgren, C, Vohl, M, Nemesh, J, Lane, C, Schaffner, S, Bolk, S, Brewer, C, Tuomi, T, Gaudet, D, Hudson, T, Daly, M, Groop, L, Lander, E

Gene expression profiling in skeletal muscle of subjects with different glycaemic tolerance. nork Lindgren, C, Lehar, J, Hirschhorn, J, Vaag, A, Poulssen, P, Eriksson, K, Gaasenbeek, M, Ladd, C, Tamayo, P, Daly, M, Ridderstrale, M, Beck-Nielsen, H, Lander, E, Altshuler, D, Groop, L

Genomewide search for type 2 diabetes mellitus susceptibility loci in Finnish families: the Botnia study. nork Lindgren, C, Mahtani, M, Widén, E, McCarthy, M, Daly, M, Kirby, A, Reeve, M, Kruglyak, L, Parker, A, Meyer, J, Almgren, P, Lehto, M, Kanninen, T, Tuomi, T, Groop, L, Lander, E

Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland. nork Pajukanta, P, Cargill, M, Viitanen, L, Nuotio, I, Kareinen, A, Perola, M, Terwilliger, J, Kempas, E, Daly, M, Lilja, H, Rioux, J, Brettin, T, Viikari, J, Rönnemaa, T, Laakso, M, Lander, E, Peltonen, L

Detecting recent positive selection in the human genome from haplotype structure. nork Sabeti, P, Reich, D, Higgins, J, Levine, H, Richter, D, Schaffner, S, Gabriel, S, Platko, J, Patterson, N, McDonald, G, Ackerman, H, Campbell, S, Altshuler, D, Cooper, R, Kwiatkowski, D, Ward, R, Lander, E

Identifying recent adaptations in large-scale genomic data. nork Grossman, SR, Andersen, K, Shlyakhter, I, Tabrizi, S, Winnicki, S, Yen, A, Park, D, Griesemer, D, Karlsson, E, Wong, S, Cabili, M, Adegbola, R, Bamezai, R, Hill, A, Vannberg, F, Rinn, J, Lander, E, Schaffner, S, Sabeti, P

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. nork Mootha, V, Lindgren, C, Eriksson, K, Subramanian, A, Sihag, S, Lehar, J, Puigserver, P, Carlsson, E, Ridderstråle, M, Laurila, E, Houstis, N, Daly, M, Patterson, N, Mesirov, J, Golub, T, Tamayo, P, Spiegelman, B, Lander, E, Hirschhorn, J, Altshuler, D, Groop, L

New models of collaboration in genome-wide association studies: the Genetic Association Information Network. nork Manolio, T, Rodriguez, L, Brooks, L, Abecasis, G, Ballinger, D, Daly, M, Donnelly, P, Faraone, S, Frazer, K, Gabriel, S, Gejman, P, Guttmacher, A, Harris, E, Insel, T, Kelsoe, JR, Lander, E, McCowin, N, Mailman, MD, Nabel, E, Ostell, J, Pugh, E, Sherry, S, Sullivan, P, Thompson, J, Warram, J

Genome-wide detection and characterization of positive selection in human populations. nork Sabeti, P, Varilly, P, Fry, B, Lohmueller, J, Hostetter, E, Cotsapas, C, Xie, X, Byrne, E, McCarroll, SA, Gaudet, R, Schaffner, S, Lander, E, Frazer, K, Ballinger, D, Cox, DR, Hinds, D, Stuve, L, Gibbs, R, Belmont, J, Boudreau, A, Hardenbol, P, Leal, S, Pasternak, S, Wheeler, D, Willis, T

Initial sequencing and analysis of the human genome. nork Lander, E, Linton, L, Birren, B, Nusbaum, C, Zody, M, Baldwin, J, Devon, K, Dewar, K, Doyle, M, FitzHugh, W, Funke, R, Gage, D, Harris, K, Heaford, A, Howland, J, Kann, L, Lehoczky, J, LeVine, R, McEwan, P, McKernan, K, Meldrim, J, Mesirov, J, Miranda, C, Morris, W, Naylor, J