CXCR1/2 Inhibitor Ladarixin Ameliorates the Insulin Resistance of 3T3-L1 Adipocytes by Inhibiting Inflammation and Improving Insulin Signaling by Vanessa Castelli, Laura Brandolini, Michele d’Angelo, Cristina Giorgio, Margherita Alfonsetti, Pasquale Cocchiaro, Francesca Lombardi, Annamaria Cimini, Marcello Allegretti

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Emerging Role of C5 Complement Pathway in Peripheral Neuropathies: Current Treatments and Future Perspectives by Cristina Giorgio, Mara Zippoli, Pasquale Cocchiaro, Vanessa Castelli, Giustino Varrassi, Andrea Aramini, Marcello Allegretti, Laura Brandolini, Maria Candida Cesta

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Intranasal delivery of NGF rescues hearing impairment in aged SAMP8 mice by Vanessa Castelli, Michele d’Angelo, Francesca Zazzeroni, Davide Vecchiotti, Edoardo Alesse, Daria Capece, Laura Brandolini, Franca Cattani, Andrea Aramini, Marcello Allegretti, Annamaria Cimini

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Inflammation-Independent Antinociceptive Effects of DF2755A, a CXCR1/2 Selective Inhibitor: A New Potential Therapeutic Treatment for Peripheral Neuropathy Associated to Non-Ulcera... by Laura Brandolini, Andrea Aramini, Gianluca Bianchini, Anna Ruocco, Riccardo Bertini, Rubina Novelli, Patrizia Angelico, Anna Elisa Valsecchi, Roberto Russo, Vanessa Castelli, Annamaria Cimini, Marcello Allegretti

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S-Carboxymethyl Cysteine Protects against Oxidative Stress and Mitochondrial Impairment in a Parkinson’s Disease In Vitro Model by Mariano Catanesi, Laura Brandolini, Michele d’Angelo, Maria Grazia Tupone, Elisabetta Benedetti, Margherita Alfonsetti, Massimiliano Quintiliani, Maddalena Fratelli, Daniela Iaconis, Annamaria Cimini, Vanessa Castelli, Marcello Allegretti

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Binding Mode Exploration of B1 Receptor Antagonists’ by the Use of Molecular Dynamics and Docking Simulation—How Different Target Engagement Can Determine Different Biological Effe... by Marica Gemei, Carmine Talarico, Laura Brandolini, Candida Manelfi, Lorena Za, Silvia Bovolenta, Chiara Liberati, Luigi Del Vecchio, Roberto Russo, Carmen Cerchia, Marcello Allegretti, Andrea Rosario Beccari

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MicroRNAs Expression in Response to rhNGF in Epithelial Corneal Cells: Focus on Neurotrophin Signaling Pathway by Chiara Compagnoni, Veronica Zelli, Andrea Bianchi, Antinisca Di Marco, Roberta Capelli, Davide Vecchiotti, Laura Brandolini, Anna Maria Cimini, Francesca Zazzeroni, Marcello Allegretti, Edoardo Alesse, Alessandra Tessitore

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L-Methionine Protects against Oxidative Stress and Mitochondrial Dysfunction in an In Vitro Model of Parkinson’s Disease by Mariano Catanesi, Laura Brandolini, Michele d’Angelo, Elisabetta Benedetti, Maria Grazia Tupone, Margherita Alfonsetti, Enrico Cabri, Daniela Iaconis, Maddalena Fratelli, Annamaria Cimini, Vanessa Castelli, Marcello Allegretti

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Intravital Microscopic Evaluation of the Effects of a CXCR2 Antagonist in a Model of Liver Ischemia Reperfusion Injury in Mice by Thiago Henrique Caldeira de Oliveira, Thiago Henrique Caldeira de Oliveira, Pedro Elias Marques, Fariba Poosti, Pieter Ruytinx, Flávio Almeida Amaral, Laura Brandolini, Marcello Allegretti, Paul Proost, Mauro Martins Teixeira

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Ergogenic Effect of BCAAs and L-Alanine Supplementation: Proof-of-Concept Study in a Murine Model of Physiological Exercise by Paola Mantuano, Gianluca Bianchini, Ornella Cappellari, Brigida Boccanegra, Elena Conte, Francesca Sanarica, Antonietta Mele, Giulia M. Camerino, Laura Brandolini, Marcello Allegretti, Michela De Bellis, Andrea Aramini, Annamaria De Luca

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Differential Effects of Nonsteroidal Anti-Inflammatory Drugs in an In Vitro Model of Human Leaky Gut by Michele d’Angelo, Laura Brandolini, Mariano Catanesi, Vanessa Castelli, Cristina Giorgio, Margherita Alfonsetti, Mara Tomassetti, Mara Zippoli, Elisabetta Benedetti, Maria Candida Cesta, Sandro Colagioia, Pasquale Cocchiaro, Annamaria Cimini, Marcello Allegretti

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Combination Drug Therapy for the Management of Chronic Neuropathic Pain by Serena Boccella, Lidia De Filippis, Cristina Giorgio, Laura Brandolini, Meghan Jones, Rubina Novelli, Ezio Amorizzo, Matteo Luigi Giuseppe Leoni, Gaetano Terranova, Sabatino Maione, Livio Luongo, Manuela Leone, Marcello Allegretti, Enrico Maria Minnella, Andrea Aramini

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CXCR1 and CXCR2 Inhibition by Ladarixin Improves Neutrophil-Dependent Airway Inflammation in Mice by Matheus Silverio Mattos, Maximiliano Ruben Ferrero, Lucas Kraemer, Gabriel Augusto Oliveira Lopes, Diego Carlos Reis, Geovanni Dantas Cassali, Fabricio Marcus Silva Oliveira, Laura Brandolini, Marcello Allegretti, Cristiana Couto Garcia, Marco Aurélio Martins, Mauro Martins Teixeira, Remo Castro Russo, Remo Castro Russo

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The CXCR1/CXCR2 Inhibitor Reparixin Alters the Development of Myelofibrosis in the Gata1low Mice by Paola Verachi, Francesca Gobbo, Francesca Gobbo, Fabrizio Martelli, Andrea Martinelli, Giuseppe Sarli, Andrew Dunbar, Andrew Dunbar, Ross L. Levine, Ross L. Levine, Ross L. Levine, Ronald Hoffman, Maria Teresa Massucci, Laura Brandolini, Cristina Giorgio, Marcello Allegretti, Anna Rita Migliaccio, Anna Rita Migliaccio

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Ketoprofen, lysine and gabapentin co-crystal magnifies synergistic efficacy and tolerability of the constituent drugs: Pre-clinical evidences towards an innovative therapeutic appr... by Andrea Aramini, Gianluca Bianchini, Samuele Lillini, Mara Tomassetti, Niccolò Pacchiarotti, Daniele Canestrari, Pasquale Cocchiaro, Rubina Novelli, Maria Concetta Dragani, Ferdinando Palmerio, Simone Mattioli, Simone Bordignon, Michele d’Angelo, Vanessa Castelli, Francesco d’Egidio, Sabatino Maione, Livio Luongo, Serena Boccella, Annamaria Cimini, Laura Brandolini, Michele Remo Chierotti, Marcello Allegretti

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Paclitaxel binds and activates C5aR1: A new potential therapeutic target for the prevention of chemotherapy-induced peripheral neuropathy and hypersensitivity reactions by Laura Brandolini, Michele d’Angelo, Rubina Novelli, Vanessa Castelli, Cristina Giorgio, Anna Sirico, Pasquale Cocchiaro, Francesco D’Egidio, Elisabetta Benedetti, Claudia Cristiano, Antonella Bugatti, Anna Ruocco, Pier Giorgio Amendola, Carmine Talarico, Candida Manelfi, Daniela Iaconis, Andrea Beccari, Andreza U. Quadros, Thiago M. Cunha, Arnaldo Caruso, Roberto Russo, Annamaria Cimini, Andrea Aramini, Marcello Allegretti

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C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps by Bruna M. Silva, Giovanni F. Gomes, Flavio P. Veras, Seppe Cambier, Gabriel V.L. Silva, Andreza U. Quadros, Diego B. Caetité, Daniele C. Nascimento, Camilla M. Silva, Juliana C. Silva, Samara Damasceno, Ayda H. Schneider, Fabio Beretta, Sabrina S. Batah, Icaro M.S. Castro, Isadora M. Paiva, Tamara Rodrigues, Ana Salina, Ronaldo Martins, Guilherme C.M. Cebinelli, Naira L. Bibo, Daniel M. Jorge, Helder I. Nakaya, Dario S. Zamboni, Luiz O. Leiria, Alexandre T. Fabro, José C. Alves-Filho, Eurico Arruda, Paulo Louzada-Junior, Renê D. Oliveira, Larissa D. Cunha, Pierre Van Mol, Lore Vanderbeke, Simon Feys, Els Wauters, Laura Brandolini, Andrea Aramini, Fernando Q. Cunha, Jörg Köhl, Marcello Allegretti, Diether Lambrechts, Joost Wauters, Paul Proost, Thiago M. Cunha

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